Protein Alignment Cyp12a5 and cyp27c1

DIOPT Version :9

• Sequence 1: NP_650782.1
• Gene: Cyp12a5 / 42293
• FlyBaseID: FBgn0038680
• Length: 536
• Species: Drosophila melanogaster
• Sequence 2: NP_001011341.1
• Gene: cyp27c1 / 496805
• XenbaseID: XB-GENE-6257635
• Length: 469
• Species: Xenopus tropicalis
• Alignment Length: 506
• Identity: 125/506 - (24%)
• Similarity: 244/506 - (48%)
• Gaps: 71/506 - (14%)

  Fly    53 ANILSLFAKSALPGGKYKNLEMMEMIDALRQDYGNII-------FLPGMMGRDGLVMTHNPKDFE 110
            ||::..|.:...  |:.:.::...     .:.||.|.       |:..:..:|.:..
 Frog     8 ANLVEFFWRDGF--GRIQEIQQKH-----ARQYGRIFKSHFGPQFVVSIADKDMVAQ-------- 57

  Fly   111 VVFRNEGVWPFRPGSDILRYHRTVYRKDFFDGVQGIIPSQGKSWGDFRSIVNPVLMQPKNVRLYF 175
             |.|.|...|.|...:....:|.:..:.     .|:|.::|:.|.:.||::...:::|::|.:|
 Frog    58 -VLRAERDAPQRANMESWHEYRELRGRS-----TGLISAEGEKWLNMRSVLRQKILRPRDVAMY- 115

  Fly   176 KKMSQVNQEFVELIKEIRDASTQEVPGNFLETIN----RWTLESVSVVALDKQLGLL-----RES 231
              ...||:...:|:|.||....||..|..:..:|    ::::|:::.:..:.:||.|     :::
 Frog   116 --SGGVNEVVEDLVKRIRKLRVQESDGLTVTNVNDLYFKYSMEAIATILYECRLGCLDDQIPQQT 178

  Fly   232 GKNSEATKLFKYLDEFFLHSADL-----EMKPSLWRYFKTPLLKKMLRTMDSVQEVTLKYVDEAI 291
            .:..||.:|...:.:..:::..:     .:.|..||.|        .|:.|.:.:.:..:||:.:
 Frog   179 KEYIEALELMFSMFKTTMYAGAIPKWLRPLIPKPWREF--------CRSWDGLFKFSQIHVDDRL 235

  Fly   292 ERLEKEAKEGVVRPEHEQSVLEKLL---KVDKKVATVMAMDMLMAGVDTTSSTFTALLLCLAKNP 353
            .::|.:.::|   .|.:..||..||   ::|.:.......:||:|||||||.|.:.....|||||
 Frog   236 RQIESQLEKG---EEVQGGVLTHLLLSKELDLEEIYANMTEMLLAGVDTTSFTLSWATYLLAKNP 297

  Fly   354 EKQARLREEVMKVLPNKDSEFTEASMKNVPYLRACIKESQRVYPLVIGNARGLTRDSVISGYRVP 418
            ..|..:.:::::.. .||...|...:..:|.:||.:||:.|::|::.||.|....|.|:.||.:|
 Frog   298 GIQEAVYQQIVQNF-GKDQVPTAEDVPKMPLVRAVVKETLRLFPVLPGNGRVTQDDLVVGGYFIP 361

  Fly   419 AGTIVSMIPINSLYSEEYFPKPTEFLPERWLRNASDSAGKCPANDLKTKNPFVFLPFGFGPRMCV 483
            .||.:::...::.|..|.||...||.||||:|          :.:|:.|..|..:|||:|.|.|:
 Frog   362 KGTQLALCHYSTSYDAECFPAAEEFRPERWIR----------SGNLERKENFGSIPFGYGIRSCI 416

  Fly   484 GKRIVEMELELGTARLIRNFNVEFNHSTKNAF-RSALINLPNIPLKFKFTD 533
            |:|:.|:|:.|...:|::||.::.:..|.... ::..:..|...:..:|.|
 Frog   417 GRRVAELEMHLLLIQLLQNFEIKPSPQTTTVLPKTHGLLCPGGKINVRFVD 467

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp12a5	NP_650782.1	p450	81..531	CDD:278495	119/474 (25%)
cyp27c1	NP_001011341.1	p450	2..457	CDD:306555	122/494 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	193	1.000	Domainoid score	I3126
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D185685at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010