Protein Alignment Cyp12a5 and Cyp4p1

DIOPT Version :10

• Sequence 1: NP_650782.1
• Gene: Cyp12a5 / 42293
• FlyBaseID: FBgn0038680
• Length: 536
• Species: Drosophila melanogaster
• Sequence 2: NP_524828.1
• Gene: Cyp4p1 / 45524
• FlyBaseID: FBgn0015037
• Length: 513
• Species: Drosophila melanogaster
• Alignment Length: 524
• Identity: 113/524 - (21%)
• Similarity: 204/524 - (38%)
• Gaps: 116/524 - (22%)

  Fly    41 WLQAKPFEEIPKAN----ILSLFAKSALPGGKYKNLEMMEMIDALRQD---YGNIIFLPGMMGRD 98
            ||.        :||    |||.|.|..    :.|:...:|:|..:.:.   :||.:.|.|
  Fly    16 WLH--------RANKDYHILSFFTKRI----RLKDGTPVEIIAPIAKGKTIFGNTLDLYG----- 63

  Fly    99 GLVMTHNPKDFEVVFRNEGVWPFRPGSDILRYHRTVYRKDFFDGVQ------------------- 144
                    :|...||..........|:..:.|   |:.|..::.:.
  Fly    64 --------RDHAGVFNYSRERAKEMGTSYIEY---VFGKAIYNIIDADSAENVLNHPNLITKGLV 117

  Fly   145 ----------GIIPSQGKSWGDFRSIVNPVLMQPKNVRLYFKKMSQVNQEFVELIKE------IR 193
                      |::.|.||.|...|.::.|.        .:|..::|    |.|:.|.      ::
  Fly   118 YNFLHPFLRTGLLTSTGKKWHARRKMLTPT--------FHFNILNQ----FQEIFKTESQKFLLQ 170

  Fly   194 DASTQEVPGNFLETINRWTLESVSVVALDKQLGLLRESGKNSEATKLFKYLDEFFLHSADLEMKP 258
            .....||.....:.|.|:||.|:...|:..:|..:.|.|......  |..::|.|:....   .|
  Fly   171 FEGQDEVTITLHDVIPRFTLNSICETAMGVKLDEMAEKGDRYREN--FSQIEECFIRRLS---NP 230

  Fly   259 SLW--RYFKTPLLKKMLRTMDSV----QEVTLKYVDEAIERLEKEAK----EGVVRPEHEQSVLE 313
            .||  :.|:....|.....:|.|    .|:..|..|...:.|:|.:.    :|.| .:...::|:
  Fly   231 LLWGDKLFEMFAAKDFASALDVVHRFSSEIIAKRRDLLKDELDKSSSTADDDGFV-SKKRFAMLD 294

  Fly   314 KLLKVDK-----KVATVMAMDMLM-AGVDTTSSTFTALLLCLAKNPEKQARLREEVMKVLPNKDS 372
            .|:..:|     .:.....:|.|| .|.||||......|:.::.||:||....:|:.:.:.:..|
  Fly   295 TLIYAEKDGLIDHIGICEEVDTLMFEGYDTTSIGLIFGLMNMSLNPDKQELCYQEIQEHIDDDLS 359

  Fly   373 EFTEASMKNVPYLRACIKESQRVYPLV-IGNARGLTRDSVISGYRVPAGTIVSMIPINSLYSEEY 436
            ......:..:.||...:||:.|::|.| |.....:....:.:|..:|.|..:::...:...:.:|
  Fly   360 NLDVGQLNKLKYLEYFMKETTRLFPSVPIMGREAVQETELANGLILPKGAQITIHVFDIHRNAKY 424

  Fly   437 FPKPTEFLPERWLRNASDSAGKCPANDLKTKNPFVFLPFGFGPRMCVGKRIVEMELELGTARLIR 501
            :..|.||.|||:|          |.| ::.::.:.::||..|.|.|:||:....|::.....|::
  Fly   425 WDSPEEFRPERFL----------PEN-VQDRHTYAYVPFSAGQRNCIGKKYAMQEMKTLMVVLLK 478

  Fly   502 NFNV 505
            .|.|
  Fly   479 QFKV 482

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp12a5	NP_650782.1	CYP24A1-like	82..528	CDD:410677	101/479 (21%)
Cyp4p1	NP_524828.1	CYP4	87..507	CDD:410721	93/428 (22%)