Protein Alignment Cyp12a5 and cyp27b1

DIOPT Version :9

• Sequence 1: NP_650782.1
• Gene: Cyp12a5 / 42293
• FlyBaseID: FBgn0038680
• Length: 536
• Species: Drosophila melanogaster
• Sequence 2: NP_001006907.1
• Gene: cyp27b1 / 448754
• XenbaseID: XB-GENE-942527
• Length: 506
• Species: Xenopus tropicalis
• Alignment Length: 519
• Identity: 135/519 - (26%)
• Similarity: 238/519 - (45%)
• Gaps: 66/519 - (12%)

  Fly     8 LNILQSQKPIVFSASQQRWQTNVPTAEIRNDPEWLQA-KPFEEIPKANILS----LFAKSALPGG 67
            |.:..|:...:|...|:.|...|    ::|..:.::. |...::|..:.:|    ||.:..|...
 Frog     5 LKLGSSRSSQLFRGLQELWAETV----LKNSEKVIKGHKSLADMPGPSTVSFISDLFCRRGLARL 65

  Fly    68 KYKNLEMMEMIDALRQDYGNIIFLPGMMGRDGLVMT-H--NPKDFEVVFRNEGVWPFRPGSDILR 129
            ....||            |...|.|......|.::| |  .|...|.|.|.||..|.|  ||:..
 Frog    66 HELQLE------------GKAKFGPVWKASFGPILTVHVAEPSLIEQVLRQEGKHPIR--SDLSS 116

  Fly   130 YHRTVYRKDFFD---GVQGIIPSQGKSWGDFRSIVNPVLMQPKNVRLYFKKMSQVNQEFVELIKE 191
            :      ||:..   ...|::.::|:.|..||||:...:::||.|..|...::.|..:.::.|..
 Frog   117 W------KDYRQCRGHSYGLLTAEGEEWQQFRSILGKHMLKPKEVEAYSDVLNDVVGDLIKKINY 175

  Fly   192 IRDASTQEVPGNFLETINRWTLESVSVVALDKQLGLLRESGKNSEATKLFKYLDEFFLHS-ADLE 255
            .|..:...|..:..:....:.||.:|.|..:.::|.| |.....|..|..:.::..|:.: ..:.
 Frog   176 QRSQNQNNVVKDIAKEFYMFGLEGISSVLFESRIGCL-EPTVPKETEKFIQSINTMFVMTLLTMA 239

  Fly   256 MKPSLWRYFKTPLLKKMLRTMDSVQEVTLKYVDEAIERLEKEAKEGVVRPEHEQSVLEKLL---- 316
            |...|.:.|:.| .:|...:.|.:......::|:.::.:.::..:|       :.|..|.|
 Frog   240 MPKFLHKIFRKP-WQKFCESWDYMFAFAKGHIDKRMKDVAQKLAQG-------EKVEGKYLTYYL 296

  Fly   317 ---KVDKKVATVMAMDMLMAGVDTTSSTFTALLLCLAKNPEKQARLREEVMKVLPNKDSEFTEAS 378
               |:..|.......::|:|||||.|||.:..|..||::|:.|:.:..||.::|..|... :.:.
 Frog   297 AQEKIPMKSIYGNVTELLLAGVDTISSTLSWSLYELAQHPDIQSAVYSEVEEILQGKQIP-SPSD 360

  Fly   379 MKNVPYLRACIKESQRVYPLVIGNARGLT-RDSVISGYRVPAGTIVSMIPINSLYSEEYFPKPTE 442
            :..:|.|:|.:||..|:||::.||||.:. ||..:..|.:|..|::::....:...|..|..|.|
 Frog   361 VARMPLLKAVVKEVLRLYPVIPGNARVVADRDIQVGDYIIPKKTLITLCHYATSRDENVFSNPNE 425

  Fly   443 FLPERWLRNASDSAGKCPANDLKTKNPFVFLPFGFGPRMCVGKRIVEMELELGTARLIRNFNVE 506
            |.|:|||:...            |.:|:..||||||.|.|:|:||.|:|:.|..||::.:|.|:
 Frog   426 FQPDRWLKKED------------THHPYASLPFGFGKRSCIGRRIAELEVYLALARILSHFEVK 477

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp12a5	NP_650782.1	p450	81..531	CDD:278495	120/441 (27%)
cyp27b1	NP_001006907.1	p450	45..503	CDD:365848	127/475 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	193	1.000	Domainoid score	I3126
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	208	1.000	Inparanoid score	I3591
OMA	1	1.010	-	-		QHG48087
OrthoDB	1	1.010	-	-		D185685at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm9361
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X156
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.980