Protein Alignment Cyp12a5 and Cyp12e1

DIOPT Version :9

• Sequence 1: NP_650782.1
• Gene: Cyp12a5 / 42293
• FlyBaseID: FBgn0038680
• Length: 536
• Species: Drosophila melanogaster
• Sequence 2: NP_650003.4
• Gene: Cyp12e1 / 41272
• FlyBaseID: FBgn0037817
• Length: 522
• Species: Drosophila melanogaster
• Alignment Length: 495
• Identity: 215/495 - (43%)
• Similarity: 319/495 - (64%)
• Gaps: 13/495 - (2%)

  Fly    43 QAKPFEEIPKANILSLFAKSALPGGKYKNLEMMEMIDALRQDYGNIIFLPGMMGRDGLVMTHNPK 107
            :|||:.:||..:.|.|. ::.||||.||||.:.||...:.:.||:|..:|.:.|.| ||:|.||:
  Fly    34 EAKPYADIPGPSKLQLI-RAFLPGGLYKNLPVHEMFLDMNRQYGSIFRMPSVAGTD-LVLTMNPQ 96

  Fly   108 DFEVVFRNEGVWPFRPGSDILRYHRTVYRKDFFDGVQGIIPSQGKSWGDFRSIVNPVLMQPKNVR 172
            |:||:|||||.:|:|...:::.|.:.|:|::.|||..|:....|.:||..|:.|||:|:||:|.:
  Fly    97 DYEVIFRNEGQYPYRRSFEVMDYFKRVHRREVFDGYDGLTSGNGPAWGKMRTAVNPILLQPRNAK 161

  Fly   173 LYFKKMSQVNQEFVELIKEIRDASTQEVPGNFLETINRWTLESVSVVALDKQLGLLRESGKNSEA 237
            ||...:.||:.||:|.|:.|||..|||:|.:|...|....:||:..|||:..||||.|...|.:.
  Fly   162 LYMTNLVQVSDEFLERIRIIRDPVTQEMPDDFAVDIRHLVIESICSVALNTHLGLLGEQRNNKDI 226

  Fly   238 TKLFKYLDEFFLHSADLEMKPSLWRYFKTPLLKKMLRTMDSVQEVTLKYVDEAIERLEKEAKEGV 302
            .||...|.:.......|::.|:.|:|...|..||::|::|::.:....::..|::|:|::||.|.
  Fly   227 QKLVLALQDVVELGFQLDIMPAFWKYLPMPNFKKLMRSLDTITDFCYFHIGNALKRIEEDAKAGT 291

  Fly   303 VRP-EHEQSVLEKLLKVDKKVATVMAMDMLMAGVDTTSSTFTALLLCLAKNPEKQARLREEVMKV 366
            :.. ..|.|:||||.:.|::.|.::|||:|.||.|.|..|...:|..|:|:|:|||||.||:..:
  Fly   292 LNEIGLETSLLEKLARFDRQTAVIIAMDLLFAGADPTLVTLGGILFSLSKSPDKQARLLEEIRGI 356

  Fly   367 LPNKDSEFTEASMKNVPYLRACIKESQRVYPLVIGNARGLTRDSVISGYRVPAGTIVSMIPINSL 431
            ||||||..|..:|:|:|||||||||..|:||:..|..|.:..|.|:|||||.|||.|.:.....:
  Fly   357 LPNKDSSLTIENMRNLPYLRACIKEGIRMYPIGPGTLRRMPHDVVLSGYRVVAGTDVGIAANYQM 421

  Fly   432 YS-EEYFPKPTEFLPERWLRNASDS--AGKCPANDLKTKNPFVFLPFGFGPRMCVGKRIVEMELE 493
            .: |::.||..||:||||||:.|:|  .|       :|..||::||||||||.|.|||||:|.||
  Fly   422 ANMEQFVPKVREFIPERWLRDESNSHLVG-------ETATPFMYLPFGFGPRSCAGKRIVDMMLE 479

  Fly   494 LGTARLIRNFNVEFNHSTKNAFRSALINLPNIPLKFKFTD 533
            :..:||:|||.:.|::..:|||::.....||||.||||.:
  Fly   480 IAISRLVRNFKIGFDYPIENAFKAQFFVQPNIPFKFKFIE 519

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp12a5	NP_650782.1	p450	81..531	CDD:278495	196/453 (43%)
Cyp12e1	NP_650003.4	p450	63..517	CDD:299894	198/461 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45445004
Domainoid	1	1.000	199	1.000	Domainoid score	I1783
eggNOG	1	0.900	-	-		E2759_KOG0159
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	201	1.000	Inparanoid score	I3768
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D185685at33208
OrthoFinder	1	1.000	-	-		FOG0000720
OrthoInspector	1	1.000	-	-		mtm6352
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24305
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X156
	10	9.900