Protein Alignment Cyp12a5 and Cyp4d20

DIOPT Version :10

• Sequence 1: NP_650782.1
• Gene: Cyp12a5 / 42293
• FlyBaseID: FBgn0038680
• Length: 536
• Species: Drosophila melanogaster
• Sequence 2: NP_647723.2
• Gene: Cyp4d20 / 38311
• FlyBaseID: FBgn0035344
• Length: 510
• Species: Drosophila melanogaster
• Alignment Length: 508
• Identity: 113/508 - (22%)
• Similarity: 212/508 - (41%)
• Gaps: 118/508 - (23%)

  Fly    59 FAKSALPG---------GKYKNLEMMEMIDALRQDYGNIIFLPGMMGR---------------DG 99
            |.|||:||         |          :.||.....|||   |.:|.               :.
  Fly    28 FEKSAIPGPISIPILGCG----------LQALHLGAENII---GWVGEKFDKYGKTFRFWILGES 79

  Fly   100 LVMTHNPKDFEVVFRNEGVWPFRPGSDILRYHRTV-YRKDFFDGVQGIIPSQGKSWGDFRSIVNP 163
            |:.|.:.:.||.:..:         :.:|...:.. |.:.|.:  .|::.|.|:.|...|.|...
  Fly    80 LIYTKDLQYFETILSS---------TTLLEKGQLYEYLRPFLN--DGLLVSTGRKWHARRKIFTH 133

  Fly   164 VLMQPKNVRLYFKKMSQVNQEFVELIKEIRDASTQEVPGNFLETINRWTLESVSVVALDKQLGLL 228
            . ...|.:..|.:.|.:.:...|:.::::.|..|..   :.|:.::...|:.::..|:..|:
  Fly   134 A-FHFKVLEHYVEIMDRHSSVMVDNLRKVADGKTAV---DMLKYVSLAALDVITEAAMGVQV--- 191

  Fly   229 RESGKNSEATKLFKYL-----------DEFFLHSADLEMKPSLWRY-FKTPLL-KKMLRTMDSVQ 280
                 |::....|.|:           |..|..|....     |.: ...||| :::|..:..:.
  Fly   192 -----NAQNDPDFPYIKALKSVVYIQPDRMFRFSRRYN-----WLFPLAAPLLHRQLLSDIRVMH 246

  Fly   281 EVTLKYVDEAIERLEKEAKEGVVRP----------EHEQSVLEKLLK------------VDKKVA 323
            :.|.|.:.|..|.:.:...:|..||          :.:.::|:.||:            :.::|.
  Fly   247 DFTDKVISERRETVRRAKADGTYRPLSLGDAEIGSKSQMALLDILLQSSINNQPLSDADIREEVD 311

  Fly   324 TVMAMDMLMAGVDTTSSTFTALLLCLAKNPEKQARLREEVMKVL-PNKDSEFTEASMKNVPYLRA 387
            |.|     ..|.|||||..:..|..:|::||.|.|:.||:.:|| |:..:..|:|.::::.||..
  Fly   312 TFM-----FEGDDTTSSGVSHALYAIARHPEVQQRIFEELQRVLGPDASAPVTQAQLQDLKYLDC 371

  Fly   388 CIKESQRVYPLVIGNARGLTRDSVISGYRVPAGTIVSMIPINSLYSEEYFPKPTEFLPERWLRNA 452
            .|||:.|:||.|....|...::..|....:||.|.:.::...:.....|||.|..|.|||:|.:.
  Fly   372 VIKETMRLYPPVPAIGRHAQKELEIGDKTIPANTSIYLVLYYAHRDANYFPDPLSFRPERFLEDQ 436

  Fly   453 SDSAGKCPANDLKTKNPFVFLPFGFGPRMCVGKRIVEMELELGTARLIRNFNV 505
            ...           .|.|.::||..||:.|:|::...:|:::..::::|.:.:
  Fly   437 EQG-----------HNTFAYVPFSAGPKNCIGQKFAVLEMKVLISKVLRFYEL 478

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp12a5	NP_650782.1	CYP24A1-like	82..528	CDD:410677	104/476 (22%)
Cyp4d20	NP_647723.2	CYP4	68..501	CDD:410721	99/455 (22%)