Protein Alignment Cyp12a5 and Cyp6a20

DIOPT Version :10

• Sequence 1: NP_650782.1
• Gene: Cyp12a5 / 42293
• FlyBaseID: FBgn0038680
• Length: 536
• Species: Drosophila melanogaster
• Sequence 2: NP_611002.3
• Gene: Cyp6a20 / 36664
• FlyBaseID: FBgn0033980
• Length: 501
• Species: Drosophila melanogaster
• Alignment Length: 437
• Identity: 112/437 - (25%)
• Similarity: 182/437 - (41%)
• Gaps: 83/437 - (18%)

  Fly   129 RYH-RTVYRKDFFDGVQ-GIIPSQGKSWGDFRSIVNPVLMQPKNVRLYFKKMSQVNQEFVELIKE 191
            ::| |.|:..:..|.:. .::...|:.|...|..:.|.....| ::..|..:..|..|.:.:..|
  Fly   100 KFHDRGVFHNERDDPLSANLVNIDGQKWKTLRQKLTPTFTSGK-MKTMFPTILTVGDELIRVFGE 163

  Fly   192 IRDASTQEVPGNFLETINRWTLESVSVVA--LD-----------KQLGLL----RESGKNSEATK 239
            ...|.:..:  .....:.|:|.:.:...|  ||           .|:|..    |..||
  Fly   164 TASADSDSM--EITNVVARFTADVIGSCAFGLDCHSLSDPKAKFVQMGTTAITERRHGK------ 220

  Fly   240 LFKYLDEFFLHSADLEMKPSLWRYFKTPLLKKMLRTMDSVQEVTLKYVDEAIERLEKEAKEGVVR 304
                       |.||.:       |..|.|...||...:||||...|::...:.::...|..|.|
  Fly   221 -----------SMDLLL-------FGAPELAAKLRMKATVQEVEDFYMNIIRDTVDYRVKNNVKR 267

  Fly   305 PEHEQSVLEKLLKVD----------KKVATVMAMDMLMAGVDTTSSTFTALLLCLAKNPEKQARL 359
            .:....::|..||.|          .::| ..|....:||.:|:|:|....|..||.:.:.|.:|
  Fly   268 HDFVDMLIEMKLKFDNGDKENGLTFNEIA-AQAFIFFLAGFETSSTTMGFALYELACHQDIQDKL 331

  Fly   360 REEVMKVLPNKDSEFTEASMKNVPYLRACIKESQRVYPLVIGNARGLTR--DSVISGYRVPAGTI 422
            |.|:..||...:.:....||:.:.||...|.|:.|..|:|....|..|:  ......|.:..||.
  Fly   332 RTEINTVLKQHNGKLDYDSMREMTYLEKVIDETMRKRPVVGHLIRVATQHYQHTNPKYNIEKGTG 396

  Fly   423 VSMIPINSLYSE-EYFPKPTEFLPERWLRNASDSAGKCPANDLKTKNPFVFLPFGFGPRMCVGKR 486
            | ::|..:::.: |::|:|.:|:|||:   ..|...:.||        ..|||||.|||.|:|.|
  Fly   397 V-IVPTLAIHHDPEFYPEPEKFIPERF---DEDQVQQRPA--------CTFLPFGDGPRNCIGLR 449

  Fly   487 IVEMELELGTARLIRNFNVEFNHSTKNAFRSALINLPNIPLKFKFTD 533
            ...|::.:|.|.||.||..|| |.||..          :||:::..|
  Fly   450 FGRMQVIVGMALLIHNFKFEF-HPTKTV----------VPLEYRTDD 485

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp12a5	NP_650782.1	CYP24A1-like	82..528	CDD:410677	110/430 (26%)
Cyp6a20	NP_611002.3	CYP6-like	67..495	CDD:410679	112/437 (26%)