Protein Alignment Cyp12a5 and Cyp11b3

DIOPT Version :9

• Sequence 1: NP_650782.1
• Gene: Cyp12a5 / 42293
• FlyBaseID: FBgn0038680
• Length: 536
• Species: Drosophila melanogaster
• Sequence 2: NP_861545.1
• Gene: Cyp11b3 / 353498
• RGDID: 727886
• Length: 498
• Species: Rattus norvegicus
• Alignment Length: 524
• Identity: 139/524 - (26%)
• Similarity: 230/524 - (43%)
• Gaps: 101/524 - (19%)

  Fly    45 KPFEEIPKANILSLFAKSALPGGKYKNLEMMEMIDALR-QDYGNI-------------IFLPGMM 95
            ||||.||                :|...:.::||..|| |...|:             ||.....
  Rat    35 KPFEAIP----------------QYSRNKWLKMIQILREQSQENLHLEMHQAFQELGPIFRHSAG 83

  Fly    96 GRDGLVMTHNPKDFEVVFRNEGVWPFRPGSDILRYHRTVYRKDFFDGV-QGIIPSQGKSWGDFRS 159
            |.. :|....|:|.|.:.:.|.:.|.|...:....||.:      .|: :|:....|..|...|.
  Rat    84 GAQ-IVSVMLPEDAEKLHQVESILPRRMTLESWVAHREL------RGLRRGVFLLNGADWRFNRL 141

  Fly   160 IVNPVLMQPKNVRLYFKKMSQVNQEFVE-----LIKEIRDASTQEVPGNFLETINRWTLESVSVV 219
            .:||.::.||.|:.:...:..|.::|||     :::.:..:.:.::..|    :..:|:|:...|
  Rat   142 QLNPNMLSPKAVQSFVPFVDVVARDFVENLKKRMLENVHGSMSMDIQSN----VFNYTMEASHFV 202

  Fly   220 ALDKQLGLLRESGKNSEATKLFKYLDEFFLHSADLEMKP-SLWRYFKTPLLKKMLRTMDSVQEVT 283
            ...::|||.... .|.|:.|....|...|..:..|...| :|.|:..|.:.|....:.|.:.|
  Rat   203 ISGERLGLTGHD-LNPESLKFIHALHSMFKSTTQLMFLPKNLTRWTSTQVWKGHFESWDIISE-- 264

  Fly   284 LKYVDEAIERLEKEAKEGVVRPEHEQS-------VLEKLLKVDKKVATVMAMDMLMAGVDTTSST 341
              ||.:.|:.:.:|..||     .:||       |.:..|.:|...|.  :|:::...||||:.:
  Rat   265 --YVTKCIKNVYRELAEG-----RQQSWSVISEMVAQSTLSMDAIHAN--SMELIAGSVDTTAIS 320

  Fly   342 FTALLLCLAKNPEKQARLREEVM----KVLPNKDSEFTEASMKNVPYLRACIKESQRVYPLVIGN 402
            ....|..||:||:.|..||:|.:    .:..|     .:.:|.::|.|||.:||:.|:||:....
  Rat   321 LVMTLFELARNPDVQQALRQESLAAEASIAAN-----PQKAMSDLPLLRAALKETLRLYPIGSSL 380

  Fly   403 ARGLTRDSVISGYRVPAGTIVSMIPINSLYS----EEYFPKPTEFLPERWLRNASDSAGKCPAND 463
            .|.:..|.|:..|.|||||:|    |..|||    ...||:|..::|:||
  Rat   381 ERIVDSDLVLQNYHVPAGTLV----IIYLYSMGRNPAVFPRPERYMPQRW--------------- 426

  Fly   464 LKTKNPFVFLPFGFGPRMCVGKRIVEMELELGTARLIRNFNVEF--NHSTKNAFRSALINLPNIP 526
            |:.|..|..|.||||.|.|:|:|:.|:|:.|....:::.|.||.  ....:.|:|..|:..|.:.
  Rat   427 LERKRSFQHLAFGFGVRQCLGRRLAEVEVLLLLHHMLKIFQVETLRQEDVQMAYRFVLMPNPRLV 491

  Fly   527 LKFK 530
            |..:
  Rat   492 LTIR 495

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp12a5	NP_650782.1	p450	81..531	CDD:278495	130/488 (27%)
Cyp11b3	NP_861545.1	p450	41..494	CDD:278495	134/515 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0159
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D185685at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820