Protein Alignment Cyp12a5 and Cyp4e3

DIOPT Version :10

• Sequence 1: NP_650782.1
• Gene: Cyp12a5 / 42293
• FlyBaseID: FBgn0038680
• Length: 536
• Species: Drosophila melanogaster
• Sequence 2: NP_523527.1
• Gene: Cyp4e3 / 34291
• FlyBaseID: FBgn0015035
• Length: 526
• Species: Drosophila melanogaster
• Alignment Length: 456
• Identity: 113/456 - (24%)
• Similarity: 198/456 - (43%)
• Gaps: 88/456 - (19%)

  Fly    84 DYG--NIIFLPGMMGRDGLVMTHNPKDFEVVFRNEGVWPFRPGSDILRYHRTVYRKDFFDGV--- 143
            |||  |.:|..|....  :||| |||..|.               ||...:.:.:...:|.:
  Fly    65 DYGKDNFLFWIGYSSH--IVMT-NPKQLEY---------------ILNSQQLIQKSTIYDLLHPW 111

  Fly   144 --QGIIPSQGKSWGDFRSIVNPVLMQPKNVRLYFKKMSQ----VNQEFVELIKEIRDASTQEVPG 202
              .|::.|.|..|...|.::.|        ..:|..:..    :|:...:.:.:::.||..:...
  Fly   112 LGHGLLTSFGSKWHKHRKMITP--------SFHFNILQDFHEVMNENSAKFMTQLKKASAGDTII 168

  Fly   203 NFLETINRWTLESVSVVALDKQLGLLRESGKNSEATKLFKYLDEFFLHSADLEMKPSLWRYFKTP 267
            :|.|..|..||:.:...|:...:..:.:  ::|...:.|:.:.......|....|.|...:..||
  Fly   169 DFQEHANYLTLDVICDTAMGVPINAMEQ--RDSSIVQAFRDMCYNINMRAFHPFKRSNRVFSLTP 231

  Fly   268 LLKKMLRTMDSVQEVTLKYVDEAIERLEKEAKEGVVRPEHEQSV-------LEKLL--------- 316
            ......:|:.::|:.|...:::.:..|:    .|..:.:|:.|:       |:.||
  Fly   232 EFSAYQKTLKTLQDFTYDIIEKRVYALQ----NGGSKEDHDPSLPRKKMAFLDTLLSSTIDGRPL 292

  Fly   317 ---KVDKKVATVMAMDMLMAGVDTTSSTFTALLLCLAKNPEKQARLREEVMKVL---PNKDSEFT 375
               ::.::|:|.|     ..|.|||:|..:..:..|:::|:.|.:|..|..:|:   .|:...|.
  Fly   293 TRQEIYEEVSTFM-----FEGHDTTTSGVSFSVYLLSRHPDVQRKLYREQCEVMGHDMNRSVSFQ 352

  Fly   376 E-ASMKNVPYLRACIKESQRVYPLVIGNARGLTRDSVISGYRVPAGTIVSMIPINSLYSEEYFPK 439
            | |.||   ||...|||:|||||.|....|...:|..|:|..||.||.:::..|...|::..|..
  Fly   353 EIAKMK---YLDLFIKEAQRVYPSVPFIGRYCDKDYDINGSIVPKGTTLNLALILLGYNDRIFKD 414

  Fly   440 PTEFLPERWLRNASDSAGKCPANDLKTKNPFVFLPFGFGPRMCVGKRIVEMELELGTARLIRNFN 504
            |..|.|||:....       ||       ||.:|||..|||.|:|::...:||:...::::|:|.
  Fly   415 PHHFRPERFEEEK-------PA-------PFEYLPFSAGPRNCIGQKFALLELKTVISKVVRSFE 465

  Fly   505 V 505
            |
  Fly   466 V 466

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp12a5	NP_650782.1	CYP24A1-like	82..528	CDD:410677	113/456 (25%)
Cyp4e3	NP_523527.1	CYP4	68..519	CDD:410721	110/453 (24%)