Protein Alignment Cyp12a5 and Cyp4d21

DIOPT Version :10

• Sequence 1: NP_650782.1
• Gene: Cyp12a5 / 42293
• FlyBaseID: FBgn0038680
• Length: 536
• Species: Drosophila melanogaster
• Sequence 2: NP_609129.2
• Gene: Cyp4d21 / 34036
• FlyBaseID: FBgn0031925
• Length: 511
• Species: Drosophila melanogaster
• Alignment Length: 546
• Identity: 120/546 - (21%)
• Similarity: 235/546 - (43%)
• Gaps: 115/546 - (21%)

  Fly     6 IALNILQSQKPIVFSASQQRWQTN------------VPTAEIRNDPEWLQAKPFEEIPKANILSL 58
            |.|.|......:|:..|:::|:.|            :|.  :.|..:.|..:|      .|.:..
  Fly     3 ILLGIAVLIMTLVWDNSRKQWRVNTFEKSRILGPFTIPI--VGNGLQALTLRP------ENFIQR 59

  Fly    59 FAKSALPGGKYKNLEMMEMIDALRQDYGNIIFLPGMMGRDGLVMTHNPKDFEVVFRNEGVWPFRP 123
            |       |.|.|            .||. .|...::| :.|:.|.:.|.||.:..:..:
  Fly    60 F-------GDYFN------------KYGK-TFRLWILG-ECLIYTKDLKYFESILSSSTL----- 98

  Fly   124 GSDILRYHRTVYRKDFFDGVQGIIPSQGKSWGDFRSIVNPVLMQPKNVRLYFKKMSQVNQEFVE- 187
               :.:.|...:.:||..  .|::.|.|..|...|.::.|.        .:||.:    :.|||
  Fly    99 ---LKKAHLYRFLRDFLG--DGLLLSTGNKWTSRRKVLAPA--------FHFKCL----ENFVEI 146

  Fly   188 -------LIKEIRDASTQEVPGNFLETINRWTLESVSVVALDKQLGLLRESGKNSEATKLFK--- 242
                   :::::::.:..:...:..:.::...|:..:..|:..|:....|  .|...||..|
  Fly   147 MDRNSGIMVEKLKNYADGKTCVDLFKFVSLEALDVTTETAMGVQVNAQNE--PNFPYTKALKSVV 209

  Fly   243 YLDEFFLHSADLEMKPSLWRY-FKTPLL-KKMLRTMDSVQEVTLKYVDEAIERLEKEAKEGVVRP 305
            |::...|.|..:...   |.: ...||: :::.:.:..:|:.|.|.:.|....||:...:|..:|
  Fly   210 YIESKRLASVSMRYN---WLFPLAAPLVYRRLQKDIAIMQDFTDKVIRERRAILERARADGTYKP 271

  Fly   306 ----------EHEQSVLEKLLK--VDKK----VATVMAMDM-LMAGVDTTSSTFTALLLCLAKNP 353
                      :.:.::|:.||:  :|.|    |.....:|: :.||.|||:|..:..|..::::|
  Fly   272 LIMGDDDIGGKAKMTLLDILLQATIDNKPLSDVDIREEVDVFIFAGDDTTTSGVSHALHAISRHP 336

  Fly   354 EKQARLREEVMKVL-PNKDSEFTEASMKNVPYLRACIKESQRVYPLVIGNARGLTRDSVISGYRV 417
            :.|..:.||::.|| |:.|:..|:..:..:.||...|||:.|::|.|....|.:..|..|....:
  Fly   337 KVQECIYEELVSVLGPDPDASVTQTKLLELKYLDCVIKETMRLHPPVPILGRYIPEDLKIGEITI 401

  Fly   418 PAGTIVSMIPINSLYSEEYFPKPTEFLPERWLRNASDSAGKCPANDLKTKN---PFVFLPFGFGP 479
            |..|.:.::|.......||||.|..|.||||:             |:||.:   |..::||..||
  Fly   402 PGNTSILLMPYYVYRDPEYFPDPLVFKPERWM-------------DMKTTSNTPPLAYIPFSSGP 453

  Fly   480 RMCVGKRIVEMELELGTARLIRNFNV 505
            :.|:|::...::::...:::||::.:
  Fly   454 KNCIGQKFANLQMKALISKVIRHYEL 479

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp12a5	NP_650782.1	CYP24A1-like	82..528	CDD:410677	104/458 (23%)
Cyp4d21	NP_609129.2	CYP4	68..502	CDD:410721	103/454 (23%)