Protein Alignment Cyp12a5 and Cyp4s3

DIOPT Version :10

• Sequence 1: NP_650782.1
• Gene: Cyp12a5 / 42293
• FlyBaseID: FBgn0038680
• Length: 536
• Species: Drosophila melanogaster
• Sequence 2: NP_573003.2
• Gene: Cyp4s3 / 32444
• FlyBaseID: FBgn0030615
• Length: 495
• Species: Drosophila melanogaster
• Alignment Length: 516
• Identity: 127/516 - (24%)
• Similarity: 217/516 - (42%)
• Gaps: 119/516 - (23%)

  Fly    50 IPK-ANILSL--FAKSALPG-------GKYKNLEMMEMIDALRQDYGNIIFLPGMMGRDGLVMTH 104
            :|| .|.|.|  |||: |||       ...|..|::..:..||:.:|.:..:  ..|:|.:||..
  Fly    19 LPKILNFLRLQRFAKT-LPGPTIGELIANVKKGEILNWLKELREKHGPVFRI--WFGKDLMVMFT 80

  Fly   105 NPKDFEVVFRNEGVWPFRPGSDILRYHRTVYRKDFFDGVQGIIPSQGKSWGDFRSIVNPVLMQPK 169
            :|:|.:.:..|         :.:|...|.....:.:.| :|::.:.|:||...|.::.|
  Fly    81 DPEDIKQLLGN---------NQLLTKSRNYELLEPWLG-KGLLTNGGESWHRRRKLLTP------ 129

  Fly   170 NVRLYFKKMSQVNQEFVE----LIKEIRDASTQEVPGNFLETINRWTLESVSVVALD-KQLGLLR 229
              ..:|:.:|:..:...|    |::.:|..:..| ..:....|..:.|:::...|:. |:...|:
  Fly   130 --GFHFRILSEFKEPMEENCRILVRRLRTKANGE-SFDIYPYITLFALDAICETAMGIKKHAQLQ 191

  Fly   230 ESGKNSEATK------------LFKYLDEFFLHSADLEMKPSLWRYFKTPLLKKMLRTMDSVQEV 282
            ...:..:|.:            .::.|:.||.|:     ||...|                  |.
  Fly   192 SDSEYVQAVQSICRVMHKQSFSFWQRLNVFFKHT-----KPGKER------------------EA 233

  Fly   283 TLKYVDEAIERLEKEAKEGVV------RPEHEQ---SVLEKLLKVDKKVATVM------------ 326
            .||.:.:...|:.:..:|.::      :||.||   ....:|..:|..:.|.|
  Fly   234 ALKVLHDETNRVIRLRREQLIQERNEWKPEAEQDDVGAKRRLAFLDMLLLTQMEGGAELSDTDIR 298

  Fly   327 -AMDMLM-AGVDTTSSTFTALLLCLAKNPEKQARLREEVMKVLPNKDSEFTEASMKNVPYLRACI 389
             .:|..| .|.|||||.....|..|:|||:.|.|..||.        ||......:::|||.|.|
  Fly   299 EEVDTFMFEGHDTTSSAIAFALSLLSKNPDVQQRAFEEA--------SELEGREKESMPYLEAVI 355

  Fly   390 KESQRVYPLVIGNARGLTRDSVISGYRVPAGTIVSMIPINSLYSE-EYFPKPTEFLPERWLRNAS 453
            ||:.|:||.|...:|.:..|..:....||.|..:|.: |..|:.: :.||.|..|.|:|:|.|.
  Fly   356 KETLRIYPSVPFFSRKVLEDLEVGKLTVPKGASISCL-IYMLHRDPKNFPDPERFDPDRFLVNE- 418

  Fly   454 DSAGKCPANDLKTKNPFVFLPFGFGPRMCVGKRIVEMELELGTARLIRNFNV--EFNHSTK 512
                       |..:||.|..|..|||.|:|::...:||:...|.|:|::..  :.:|..|
  Fly   419 -----------KQMHPFAFAAFSAGPRNCIGQKFAMLELKTSLAMLLRSYRFLPDKDHQPK 468

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp12a5	NP_650782.1	CYP24A1-like	82..528	CDD:410677	113/474 (24%)
Cyp4s3	NP_573003.2	CYP4	64..483	CDD:410721	112/470 (24%)