Protein Alignment Cyp12a5 and Cyp4d2

DIOPT Version :10

• Sequence 1: NP_650782.1
• Gene: Cyp12a5 / 42293
• FlyBaseID: FBgn0038680
• Length: 536
• Species: Drosophila melanogaster
• Sequence 2: NP_525043.1
• Gene: Cyp4d2 / 31192
• FlyBaseID: FBgn0011576
• Length: 501
• Species: Drosophila melanogaster
• Alignment Length: 515
• Identity: 115/515 - (22%)
• Similarity: 224/515 - (43%)
• Gaps: 115/515 - (22%)

  Fly    64 LPGGK----------YKNLEMMEMIDALRQD---YGNI--IFLPGMMGRDGLVMTHNPKDFEVVF 113
            |||.:          |:.|:..:::|.::::   ||.:  :::...:.    |.:.:|:|.|.|.
  Fly    31 LPGPRPLPFLGNLLMYRGLDPEQIMDFVKKNQRKYGRLYRVWILHQLA----VFSTDPRDIEFVL 91

  Fly   114 RNEGVWPFRPGSDILRYHRTVYRKDFFDGV-----QGIIPSQGKSWGDFRSIVNPVLMQPKNVRL 173
            .::               :.:.:.:.:..:     .|::.|.|:.|...|.|:.|.        .
  Fly    92 SSQ---------------QHITKNNLYKLLNCWLGDGLLMSTGRKWHGRRKIITPT--------F 133

  Fly   174 YFKKMSQ----VNQEFVELIKEIRDASTQEVPGNFLETINRWTLESVSVVALDKQLGLLRESGKN 234
            :||.:.|    .:|:...::::::..:....|.|....|   .|.::.::| :..:|....:.||
  Fly   134 HFKILEQFVEIFDQQSAVMVEQLQSRADGMTPINIFPVI---CLTALDIIA-ETAMGTKINAQKN 194

  Fly   235 ---------SEATKLFKYLDEFFLHSADLEMKPSLWRYFKTPLLKKMLRTMDSVQEVTLKYVDEA 290
                     ::.|.:   |.:.|:|:  .:....::|..:....|:..:.:..:.:.|...:.|.
  Fly   195 PNLPYVQAVNDVTNI---LIKRFIHA--WQRVDWIFRLTQPTEAKRQDKAIKVMHDFTENIIRER 254

  Fly   291 IERLEKEAKEGVVRPEHE---------QSVLEKLLK------------VDKKVATVMAMDMLMAG 334
            .|.|...:||  ..||.|         .::|:.||:            :.::|.|.|     ..|
  Fly   255 RETLVNNSKE--TTPEEEVNFLGQKRRMALLDVLLQSTIDGAPLSDEDIREEVDTFM-----FEG 312

  Fly   335 VDTTSSTFTALLLCLAKNPEKQARLREEVMKVL-PNKDSEFTEASMKNVPYLRACIKESQRVYPL 398
            .|||:|..:..|..::::||.|.||::|:..|| .::.|..|...:..:.::...||||.|::|.
  Fly   313 HDTTTSAISFCLYEISRHPEVQQRLQQEIRDVLGEDRKSPVTLRDLGELKFMENVIKESLRLHPP 377

  Fly   399 VIGNARGLTRDSVISGYRVPAGTIVSMIPINSLYSEEYFPKPTEFLPERWLRNASDSAGKCPAND 463
            |....|....|..|.|..:||||..:|.....|...|||..|.||.|||:     |:       |
  Fly   378 VPMIGRWFAEDVEIRGKHIPAGTNFTMGIFVLLRDPEYFESPDEFRPERF-----DA-------D 430

  Fly   464 LKTKNPFVFLPFGFGPRMCVGKRIVEMELELGTARLIRNFNV-----EFNHSTKNAFRSA 518
            :...:|:.::||..|||.|:|::...:|::...::|:|:|.:     |..||.....|||
  Fly   431 VPQIHPYAYIPFSAGPRNCIGQKFAMLEMKSTVSKLLRHFELLPLGPEPRHSMNIVLRSA 490

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp12a5	NP_650782.1	CYP24A1-like	82..528	CDD:410677	109/487 (22%)
Cyp4d2	NP_525043.1	CYP4	66..495	CDD:410721	108/480 (23%)