Protein Alignment Cyp12a5 and Cyp12d1-p

DIOPT Version :10

• Sequence 1: NP_650782.1
• Gene: Cyp12a5 / 42293
• FlyBaseID: FBgn0038680
• Length: 536
• Species: Drosophila melanogaster
• Sequence 2: NP_610635.4
• Gene: Cyp12d1-p / 246648
• FlyBaseID: FBgn0050489
• Length: 521
• Species: Drosophila melanogaster
• Alignment Length: 492
• Identity: 222/492 - (45%)
• Similarity: 326/492 - (66%)
• Gaps: 14/492 - (2%)

  Fly    45 KPFEEIPKANILSLFAKSALPGGKYKNLEMMEMIDALRQDYGNIIFLPGMMGRDGLVMTHNPKDF 109
            |.::|||:.|... |.::.:|||:::|..:.|...|:|:.||:|..:|||.||...|.|.|.||.
  Fly    40 KTYDEIPRPNKFK-FMRAFMPGGEFQNASITEYTSAMRKRYGDIYVMPGMFGRKDWVTTFNTKDI 103

  Fly   110 EVVFRNEGVWPFRPGSDILRYHRTVYRKDFFDGVQGIIPSQGKSWGDFRSIVNPVLMQPKNVRLY 174
            |:||||||:||.|.|.|.:.|.|...|.|.:..|||::.||.::||..||.:||:.|||:.:|:|
  Fly   104 EMVFRNEGIWPRRDGLDSIVYFREHVRPDVYGEVQGLVASQNEAWGKLRSAINPIFMQPRGLRMY 168

  Fly   175 FKKMSQVNQEFVELIKEIRDASTQEVPGNFLETINRWTLESVSVVALDKQLGLLRESGKNSEATK 239
            ::.:|.:|.||:|.||||||..|.|||.:|.:.|:|...||:.:||.|:|:||:|::..||:|..
  Fly   169 YEPLSNINNEFIERIKEIRDPKTLEVPEDFTDEISRLVFESLGLVAFDRQMGLIRKNRDNSDALT 233

  Fly   240 LFKYLDEFFLHSADLEMKPSLWRYFKTPLLKKMLRTMDSVQEVTLKYVDEAIERLEKEAKEGVVR 304
            ||:...:.|..:..|:::||:|:...||..:||.||::....|..|.:.|..:.|||..:.|  .
  Fly   234 LFQTSRDIFRLTFKLDIQPSMWKIISTPTYRKMKRTLNDSLNVAQKMLKENQDALEKRRQAG--E 296

  Fly   305 PEHEQSVLEKLLKVDKKVATVMAMDMLMAGVDTTSSTFTALLLCLAKNPEKQARLREEVMKVLPN 369
            ..:..|:||:|:::|.|||.:|::|:|.||||.|::..:|:||||:|:|:|||:||||::.::|.
  Fly   297 KINSNSMLERLMEIDPKVAVIMSLDILFAGVDATATLLSAVLLCLSKHPDKQAKLREELLSIMPT 361

  Fly   370 KDSEFTEASMKNVPYLRACIKESQRVYPLVIGNARGLTRDSVISGYRVPAGTIVSMIPINSLYSE 434
            |||...|.:||::|||||.|||:.|.||..:|..|....|.::||||||.||.| ::..|.|..|
  Fly   362 KDSLLNEENMKDMPYLRAVIKETLRYYPNGLGTMRTCQNDVILSGYRVPKGTTV-LLGSNVLMKE 425

  Fly   435 -EYFPKPTEFLPERWLRNASDSAGKCPANDLKTK-NPFVFLPFGFGPRMCVGKRIVEMELELGTA 497
             .|:|:|.|||||||||:        |....|.: :||.|||||||||||:|||:|::|:|...|
  Fly   426 ATYYPRPDEFLPERWLRD--------PETGKKMQVSPFTFLPFGFGPRMCIGKRVVDLEMETTVA 482

  Fly   498 RLIRNFNVEFNHSTKNAFRSALINLPNIPLKFKFTDV 534
            :|||||:||||......|::..:..|.|...|||||:
  Fly   483 KLIRNFHVEFNRDASRPFKTMFVMEPAITFPFKFTDI 519

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp12a5	NP_650782.1	CYP24A1-like	82..528	CDD:410677	205/447 (46%)
Cyp12d1-p	NP_610635.4	CYP24A1-like	76..508	CDD:410677	203/442 (46%)