Protein Alignment Cyp12a5 and Cyp6a16

DIOPT Version :10

• Sequence 1: NP_650782.1
• Gene: Cyp12a5 / 42293
• FlyBaseID: FBgn0038680
• Length: 536
• Species: Drosophila melanogaster
• Sequence 2: NP_001285631.1
• Gene: Cyp6a16 / 19836250
• FlyBaseID: FBgn0031726
• Length: 498
• Species: Drosophila melanogaster
• Alignment Length: 509
• Identity: 118/509 - (23%)
• Similarity: 208/509 - (40%)
• Gaps: 114/509 - (22%)

  Fly    67 GKYKNLEMMEMIDALRQDY----------GNIIFLPGMMGRDGLVMTHNPKDFEVVFRNEGVWPF 121
            |.:..|:.:...:.|::.|          |..:||..|    .:|:     |.::|
  Fly    41 GHFFRLQSVHYSELLQETYDAFRGSAKVAGTYVFLRPM----AVVL-----DLDLV--------- 87

  Fly   122 RPGSDILRYHRTVYRKDF--------FDG---VQGIIPSQGKSWGDFRSIVNPVLMQPKNVRLYF 175
                      :.|..:||        |.|   ...:...||:.|.:.|:.::|.....| ::..|
  Fly    88 ----------KAVLIRDFNNFVDRRSFHGDPLTANLFNLQGEEWRNLRTKLSPTFTSGK-MKYMF 141

  Fly   176 KKMSQVNQE----FVELIKEIRDASTQEVPGNFLETINRWTLESVSVVALDKQLGLLRESGKNSE 236
            ..:|.|.|:    |.||:      .:|.......:.:.|:|.:.:...|...:...|||....
  Fly   142 GTVSTVAQQLGGTFDELV------GSQGAVLELHDLMARYTTDVIGSCAFGTECSSLREPQAE-- 198

  Fly   237 ATKLFKYLDEFFLHSADLEMKPSLWRYFKTPLLKKMLRTMDSVQ----EVTLKYVDEAI-ERLEK 296
                |:.:......:::..::   ||.||...|..:.:....|:    ::| |:.:..: |.:|.
  Fly   199 ----FRQVGRRIFRNSNRSIR---WRIFKMTYLSSLAKLGLPVRILHPDIT-KFFNRIVRETVEL 255

  Fly   297 EAKEGVVRPEHEQSVLE-------KLLKVDKKVATVMAMDMLMAGVDTTSSTFTALLLCLAKNPE 354
            ..:|.:.|.:....:|:       |.|.:::..|  .|....:||.:|:||..:..|..||||.:
  Fly   256 RERENIRRNDFMDLLLDLRRQENGKGLTMEQMAA--QAFVFFVAGFETSSSNMSYALFELAKNQD 318

  Fly   355 KQARLREEVMKVLPNKDSEFTEASMKNVPYLRACIKESQRVYPLVIGNARGLTRDSVISGYRVPA 419
            .|.:||.|:...: .|..:.|..:|..:|||...|.|:.|.||.:....|..:.|     |.:|:
  Fly   319 VQQKLRMEINDSI-GKHGKLTYEAMMEMPYLDQTITETLRKYPALSSLTRLASED-----YEIPS 377

  Fly   420 -----------GTIVSMIPINSL-YSEEYFPKPTEFLPERWLRNASDSAGKCPANDLKTKNPFVF 472
                       ||.|. ||:.:: |..|.:|:|.||.|||:..:|      |     :.::|..|
  Fly   378 PDGGDPVVLEKGTSVH-IPVLAIHYDPEVYPEPHEFRPERFAPDA------C-----RERHPTAF 430

  Fly   473 LPFGFGPRMCVGKRIVEMELELGTARLIRNFNVEFNHSTKNAFRSALINLPNIP 526
            |.||.|||.|:|.|...|::::|...|:|.|.......:....:....||..:|
  Fly   431 LGFGDGPRNCIGLRFGRMQVKVGLITLLRRFRFSLPPGSPTQLKVTKRNLILLP 484

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp12a5	NP_650782.1	CYP24A1-like	82..528	CDD:410677	115/494 (23%)
Cyp6a16	NP_001285631.1	CYP6-like	64..489	CDD:410679	114/486 (23%)