Protein Alignment Cyp12a5 and cyp-44A1

DIOPT Version :10

• Sequence 1: NP_650782.1
• Gene: Cyp12a5 / 42293
• FlyBaseID: FBgn0038680
• Length: 536
• Species: Drosophila melanogaster
• Sequence 2: NP_495052.1
• Gene: cyp-44A1 / 173936
• WormBaseID: WBGene00000375
• Length: 489
• Species: Caenorhabditis elegans
• Alignment Length: 523
• Identity: 140/523 - (26%)
• Similarity: 233/523 - (44%)
• Gaps: 77/523 - (14%)

  Fly    31 PTAEIRNDPEWLQAKPFEEIPKANILSL-----FAKSALPGGKYKNLE-MMEMIDALRQDYGNII 89
            ||:.....|     :.|.|||....:.:     :.|.|:.... |.:| ..:.::.:.:.||.|:
 Worm    19 PTSSPNTPP-----RTFSEIPGPREIPVIGNIGYFKYAVKSDA-KTIENYNQHLEEMYKKYGKIV 77

  Fly    90 FLPGMMGRDGLVMTHNPKDFEVVFRNEGVWPFRPGSDILRYHRTV--YRKDFFDGVQGIIPS--- 149
            ......||..:|...:|.|.:.|...:|..||     |:....|.  ||:     ::|:.|.
 Worm    78 KENLGFGRKYVVHIFDPADVQTVLAADGKTPF-----IVPLQETTQKYRE-----MKGMNPGLGN 132

  Fly   150 -QGKSWGDFRSIVNPVLMQPKNVRLYFKKMSQVNQEFVELIKEIRD-------ASTQEVPGNFLE 206
             .|..|...||.|...:|:|::|:.|. ..||:...  :|:..:.|       ...|:|.|
 Worm   133 LNGPEWYRLRSSVQHAMMRPQSVQTYL-PFSQIVSN--DLVCHVADQQKRFGLVDMQKVAG---- 190

  Fly   207 TINRWTLESVSVVALDKQLGLLRESGKNSE-ATKLFKYLDEFFLHSADLEMKPSLWRYFKTPLLK 270
               ||:|||...:..:|.||.|   |..|| |..|.:...:.|..||.:.:...::|.|.||..:
 Worm   191 ---RWSLESAGQILFEKSLGSL---GNRSEWADGLIELNKKIFQLSAKMRLGLPIFRLFSTPSWR 249

  Fly   271 KMLRTMDSVQEVTLKYVDEAIERLEKEAKEGVVRPEHEQSVLEKLLKVDKKVATVMAMDMLMAGV 335
            ||:...|.......:.:|:|:::|:....:.  :.....|.|....:::::...|:.:.|...|:
 Worm   250 KMVDLEDQFYSEVDRLMDDALDKLKVNDSDS--KDMRFASYLINRKELNRRDVKVILLSMFSDGL 312

  Fly   336 DTTSSTFTALLLCLAKNPEKQARLREEVMKVLPNKDSEFTEASMKNVPYLRACIKESQRVYPLVI 400
            .||:......|..||.:||....:::|:.:          :.:...:.:|||||||:.|::|:..
 Worm   313 STTAPMLIYNLYNLATHPEALKEIQKEIKE----------DPASSKLTFLRACIKETFRMFPIGT 367

  Fly   401 GNARGLTRDSVISGYRVPAGTIVSMIPINSLYSEE--YFPKPTEFLPERWLRNASDSAGKCPAND 463
            ..:|...::.::|||.|||||.|. |..|.|...|  :...|.||.|:|||..:
 Worm   368 EVSRVTQKNLILSGYEVPAGTAVD-INTNVLMRHEVLFSDSPREFKPQRWLEKS----------- 420

  Fly   464 LKTKNPFVFLPFGFGPRMCVGKRIVEMELELGTARLIRNFNVEFNHSTKNAFRSALINLPNIPLK 528
             |..:||.:||||||||||.|:|..|.:|....|:|..|:::.............|: ||.....
 Worm   421 -KEVHPFAYLPFGFGPRMCAGRRFAEQDLLTSLAKLCGNYDIRHRGDPITQIYETLL-LPRGDCT 483

  Fly   529 FKF 531
            |:|
 Worm   484 FEF 486

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp12a5	NP_650782.1	CYP24A1-like	82..528	CDD:410677	127/461 (28%)
cyp-44A1	NP_495052.1	CYP24A1-like	70..478	CDD:410677	125/456 (27%)