Protein Alignment Cyp12a5 and cyp-44A1

DIOPT Version :9

• Sequence 1: NP_650782.1
• Gene: Cyp12a5 / 42293
• FlyBaseID: FBgn0038680
• Length: 536
• Species: Drosophila melanogaster
• Sequence 2: NP_495052.1
• Gene: cyp-44A1 / 173936
• WormBaseID: WBGene00000375
• Length: 489
• Species: Caenorhabditis elegans
• Alignment Length: 525
• Identity: 141/525 - (26%)
• Similarity: 230/525 - (43%)
• Gaps: 81/525 - (15%)

  Fly    31 PTAEIRNDPEWLQAKPF-EEIPKANILSLFAKSALPGGKY------KNLE-MMEMIDALRQDYGN 87
            ||:.....|......|. .|||....:..|        ||      |.:| ..:.::.:.:.||.
 Worm    19 PTSSPNTPPRTFSEIPGPREIPVIGNIGYF--------KYAVKSDAKTIENYNQHLEEMYKKYGK 75

  Fly    88 IIFLPGMMGRDGLVMTHNPKDFEVVFRNEGVWPFRPGSDILRYHRTV--YRKDFFDGVQGIIPS- 149
            |:......||..:|...:|.|.:.|...:|..||     |:....|.  ||:     ::|:.|.
 Worm    76 IVKENLGFGRKYVVHIFDPADVQTVLAADGKTPF-----IVPLQETTQKYRE-----MKGMNPGL 130

  Fly   150 ---QGKSWGDFRSIVNPVLMQPKNVRLYFKKMSQVNQEFVELIKEIRD-------ASTQEVPGNF 204
               .|..|...||.|...:|:|::|:.|. ..||:...  :|:..:.|       ...|:|.|
 Worm   131 GNLNGPEWYRLRSSVQHAMMRPQSVQTYL-PFSQIVSN--DLVCHVADQQKRFGLVDMQKVAG-- 190

  Fly   205 LETINRWTLESVSVVALDKQLGLLRESGKNSE-ATKLFKYLDEFFLHSADLEMKPSLWRYFKTPL 268
                 ||:|||...:..:|.||.|   |..|| |..|.:...:.|..||.:.:...::|.|.||.
 Worm   191 -----RWSLESAGQILFEKSLGSL---GNRSEWADGLIELNKKIFQLSAKMRLGLPIFRLFSTPS 247

  Fly   269 LKKMLRTMDSVQEVTLKYVDEAIERLEKEAKEGVVRPEHEQSVLEKLLKVDKKVATVMAMDMLMA 333
            .:||:...|.......:.:|:|:::|:....:.  :.....|.|....:::::...|:.:.|...
 Worm   248 WRKMVDLEDQFYSEVDRLMDDALDKLKVNDSDS--KDMRFASYLINRKELNRRDVKVILLSMFSD 310

  Fly   334 GVDTTSSTFTALLLCLAKNPEKQARLREEVMKVLPNKDSEFTEASMKNVPYLRACIKESQRVYPL 398
            |:.||:......|..||.:||....:::|:.:          :.:...:.:|||||||:.|::|:
 Worm   311 GLSTTAPMLIYNLYNLATHPEALKEIQKEIKE----------DPASSKLTFLRACIKETFRMFPI 365

  Fly   399 VIGNARGLTRDSVISGYRVPAGTIVSMIPINSLYSEE--YFPKPTEFLPERWLRNASDSAGKCPA 461
            ....:|...::.::|||.|||||.|. |..|.|...|  :...|.||.|:|||..:
 Worm   366 GTEVSRVTQKNLILSGYEVPAGTAVD-INTNVLMRHEVLFSDSPREFKPQRWLEKS--------- 420

  Fly   462 NDLKTKNPFVFLPFGFGPRMCVGKRIVEMELELGTARLIRNFNVEFNHSTKNAFRSALINLPNIP 526
               |..:||.:||||||||||.|:|..|.:|....|:|..|:::.............|: ||...
 Worm   421 ---KEVHPFAYLPFGFGPRMCAGRRFAEQDLLTSLAKLCGNYDIRHRGDPITQIYETLL-LPRGD 481

  Fly   527 LKFKF 531
            ..|:|
 Worm   482 CTFEF 486

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp12a5	NP_650782.1	p450	81..531	CDD:278495	128/465 (28%)
cyp-44A1	NP_495052.1	p450	34..477	CDD:299894	134/499 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	199	1.000	Domainoid score	I1783
eggNOG	1	0.900	-	-		E2759_KOG0159
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	217	1.000	Inparanoid score	I2311
Isobase	1	0.950	-	0	Normalized mean entropy	S4770
OMA	1	1.010	-	-		QHG48087
OrthoDB	1	1.010	-	-		D185685at33208
OrthoFinder	1	1.000	-	-		FOG0000720
OrthoInspector	1	1.000	-	-		otm14191
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X156
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	12	11.830