Protein Alignment Cyp12a5 and Cyp11b2

DIOPT Version :9

• Sequence 1: NP_650782.1
• Gene: Cyp12a5 / 42293
• FlyBaseID: FBgn0038680
• Length: 536
• Species: Drosophila melanogaster
• Sequence 2: NP_034121.4
• Gene: Cyp11b2 / 13072
• MGIID: 88584
• Length: 500
• Species: Mus musculus
• Alignment Length: 529
• Identity: 135/529 - (25%)
• Similarity: 232/529 - (43%)
• Gaps: 100/529 - (18%)

  Fly    39 PEWLQAKPFEEIPKANILSLFAKSALPGGKYKNLEMMEMIDALRQDYGNIIFLP----------- 92
            |:.||  |||.||                :|...:.::||..||:.....:.|.
Mouse    32 PKTLQ--PFEAIP----------------QYSRNKWLKMIQILREQGQENLHLEMHQVFRELGPI 78

  Fly    93 --GMMGRDGLVMTHNPKDFEVVFRNEGVWPFRPGSDILRYHRTVYRKDFFDGV-QGIIPSQGKSW 154
              ..:|:..:|....|:|.|.:.:.|.:.|.|...:....||.:      .|: :|:....|..|
Mouse    79 FRHSVGKTQIVSVMLPEDAEKLHQVESMLPRRMHLEPWVAHREL------RGLRRGVFLLNGPEW 137

  Fly   155 GDFRSIVNPVLMQPKNVRLYFKKMSQVNQEFVELIKE-----IRDASTQEVPGNFLETINRWTLE 214
            ...|..:|..::.||.|:.:...:..|.::|:|.:||     .|.:.|.:|.    :::..:|:|
Mouse   138 RLNRLRLNRNVLSPKAVQKFVPMVDMVARDFLETLKEKVLQNARGSLTMDVQ----QSLFNYTIE 198

  Fly   215 SVSVVALDKQLGLLRESGKNSEATKLFKYLDEFFLHSADLEMKP-SLWRYFKTPLLKKMLRTMDS 278
            :.:.....::||||... .:..:.|....|...|..::.|...| ||.|:..|.:.|:.....|.
Mouse   199 ASNFALFGERLGLLGHD-LSPGSLKFIHALHSMFKSTSQLLFLPKSLTRWTSTRVWKEHFDAWDV 262

  Fly   279 VQEVTLKYVDEAIERLEKEAK-------EGVVRPEHEQSVLEKLLKVDKKVATVMAMDMLMAGVD 336
            :.|    |.:..|.::.:|.:       .|:|    .:.:.:..|.:|...|.  :|::....||
Mouse   263 ISE----YANRCIWKVHQELRLGSSQTYSGIV----AELISQGSLPLDAIKAN--SMELTAGSVD 317

  Fly   337 TTSSTFTALLLCLAKNPEKQARLREEVM----KVLPNKDSEFTEASMKNVPYLRACIKESQRVYP 397
            ||:......|..||:||:.|..||:|.:    .:..|     .:.:|.::|.|||.:||:.|:||
Mouse   318 TTAIPLVMTLFELARNPDVQKALRQESLAAEASIAAN-----PQKAMSDLPLLRAALKETLRLYP 377

  Fly   398 LVIGNARGLTRDSVISGYRVPAGTIVSMIPINSLYS----EEYFPKPTEFLPERWLRNASDSAGK 458
            :.....|.|:.|.|:..|.|||||:|.:.    |||    ...||:|..::|:||
Mouse   378 VGGFLERILSSDLVLQNYHVPAGTLVLLY----LYSMGRNPAVFPRPERYMPQRW---------- 428

  Fly   459 CPANDLKTKNPFVFLPFGFGPRMCVGKRIVEMELELGTARLIRNFNVEF--NHSTKNAFRSALIN 521
                 |:.|..|..|.||||.|.|:|:|:.|:|:.|....:::.|.||.  ....:.|:|..|:.
Mouse   429 -----LERKRSFQHLAFGFGVRQCLGRRLAEVEMMLLLHHILKTFQVETLRQEDVQMAYRFVLMP 488

  Fly   522 LPNIPLKFK 530
            ..:..|.|:
Mouse   489 SSSPVLTFR 497

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp12a5	NP_650782.1	p450	81..531	CDD:278495	124/487 (25%)
Cyp11b2	NP_034121.4	p450	42..496	CDD:365848	127/514 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D185685at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8705
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920