DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment cdi and limk1b

DIOPT Version :9

Sequence 1:	NP_524401.2	Gene:	cdi / 42289	FlyBaseID:	FBgn0004876	Length:	1213	Species:	Drosophila melanogaster
Sequence 2:	XP_005161503.1	Gene:	limk1b / 101883214	ZFINID:	ZDB-GENE-110411-106	Length:	615	Species:	Danio rerio

Alignment Length:	391	Identity:	121/391 - (30%)
Similarity:	182/391 - (46%)	Gaps:	80/391 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    60 VKHQPLHN------GGWIGN--------GLPPAPVTRTIS--SDRLVTGSS-----C-------- 95
            ::|.|..:      .|.:|.        |..|.|..|.||  |..::...|     |
Zfish   207 IEHNPKDHIKQEDLSGLLGEELDQPGNLGFFPLPNNRQISHRSKNILRSCSIDKVPCLQRHAALL 271

  Fly    96 ---RALRTAVSALYSVDDFVK-----------EKIGSGFFSEVYKVTHRTTGQVMVLK--MNQLR 144
               |.:..:.|..:..:|..:           |.:|.|.|.:..||||..||:|||:|  :....
Zfish   272 SHRRDINRSESLRFDANDKTQRIFRPSDLIYGEILGKGCFGQAIKVTHLETGEVMVIKELLQFDE 336

  Fly   145 ANRPNMLREVQLLNKLSHANILSFMGVCVQEGQLHALTEYINGGSLEQLLANKEVVLSATQ---- 205
            ..:...|:||:::..|.|.|:|.|:|:..::.:|:.::||:.||:|      ::.:|....
Zfish   337 ETQKTFLKEVKVMRCLEHPNVLKFIGILYKDKRLNLISEYVQGGTL------RDTILKMASDHPW 395

  Fly   206 --KIRLALGIARGMSYVHDAGIFHRDLTSKNVLIRNLANDQYEAVVGDFGLA------------- 255
              ::..|..||.||:|:|...:.||||.|.|..:|    :....||.|||||
Zfish   396 NLRVSYAKDIAAGMAYLHSMNVIHRDLNSHNCFVR----ENQTVVVADFGLAQLVKDEKTSSPGQ 456

  Fly   256 -AKIPVKSRKSRLETVGSPYWVSPECLKGQWYDQTSDVFSFGIIQCEIIARIEADPDMMPRTASF 319
             :|:....||.|...||:|||::||.:.|:.||:..|:|||||:.||||.|:.||||.:|||..:
Zfish   457 MSKLNKLGRKKRYTVVGNPYWMAPEMINGKIYDERVDIFSFGIVLCEIIGRVYADPDFLPRTQEY 521

  Fly   320 GLDYLAFVELC-PMDTPPVFLRLAFYCCLYDAKSRPTFHDATKKLTLLLEKYEHESSAGASPLSS 383
            ||:...|:|.| ..|.|..|..:|..||..:|:.||.|    .||...||........|...:|.
Zfish   522 GLNVKEFLERCWSKDCPAAFFPIAVLCCALEAEKRPVF----AKLEEWLENVMMHLEMGLPLMSE 582

  Fly   384 L 384
            |
Zfish   583 L 583

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
cdi	NP_524401.2	TyrKc	113..363	CDD:197581	98/283 (35%)
cdi	NP_524401.2	PKc_like	116..370	CDD:304357	101/276 (37%)
limk1b	XP_005161503.1	LIM	<17..42	CDD:295319
		LIM2_LIMK	50..104	CDD:188751
		TyrKc	303..566	CDD:197581	100/276 (36%)
		PKc_like	306..573	CDD:304357	101/280 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D119463at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920