DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment cdi and limk2

DIOPT Version :9

Sequence 1:	NP_524401.2	Gene:	cdi / 42289	FlyBaseID:	FBgn0004876	Length:	1213	Species:	Drosophila melanogaster
Sequence 2:	NP_001135686.1	Gene:	limk2 / 100216249	XenbaseID:	XB-GENE-976145	Length:	606	Species:	Xenopus tropicalis

Alignment Length:	427	Identity:	145/427 - (33%)
Similarity:	198/427 - (46%)	Gaps:	92/427 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 EICGLSVDQVDSSAASPFIWPSTAGMCTTATTVTTSTNGDATAEAPVKHQPLHNGGWIGNGLPPA 78
            ||.|..|..:.|..|...       :|:|          |.|.:..::|.|..|.. :.|..|.:
Frog   183 EINGSPVTTLSSKEADDL-------LCST----------DRTLQLLIEHNPPPNLP-VDNAPPKS 229

  Fly    79 PVTRTI------------------SSDRLVTGSSC----------RALRTAVSALYSV----DDF 111
            |..|:|                  :|:....|:.|          .:||..|.....:    :..
Frog   230 PSFRSIEARGSTEGPMKRSSIRRSNSNTRSPGTCCPKDPRSVSRSESLRCGVGGAQQIFRPCELL 294

  Fly   112 VKEKIGSGFFSEVYKVTHRTTGQVMVLK-MNQL-RANRPNMLREVQLLNKLSHANILSFMGVCVQ 174
            ..|::|.|||....|||||.||:|||:| :.|. ...:.|.|.||:::..|.|.|:|.|:||..:
Frog   295 HGEELGKGFFGRAIKVTHRATGRVMVMKELIQFDEQTQKNFLTEVKVMRSLDHPNVLRFIGVLYK 359

  Fly   175 EGQLHALTEYINGGSLEQLLANKEVVLSATQKIRLALGIARGMSYVHDAGIFHRDLTSKNVLIRN 239
            :|:|:.|||:|..|:|:..|  :.......||:..|..||.||:|:|...|.||||.|.|.||:.
Frog   360 DGRLNLLTEFIECGTLKDYL--RADYCPWQQKVSFAKDIACGMAYLHSMSIIHRDLNSHNCLIKL 422

  Fly   240 LANDQYEAVVGDFGLAAKI------------PVK-------SRKSRLETVGSPYWVSPECLKGQW 285
                ....||.||||:..|            |.|       :||.|...||:|||::||.|.|:.
Frog   423 ----DGTTVVADFGLSRLIVEEKPLPAPDRPPTKKRTLRKNNRKKRYTVVGNPYWMAPEMLNGKD 483

  Fly   286 YDQTSDVFSFGIIQCEIIARIEADPDMMPRTASFGLDYLAFVE-LCPMDTPPVFLRLAFYCCLYD 349
            ||:..|:|||||:.||||.::.||||.:|||..|||:...|.| ..|.|.||.|..||..||..:
Frog   484 YDEKVDIFSFGIVLCEIIGQVYADPDCLPRTLDFGLNVRLFWEKFVPKDCPPGFFPLATSCCHLE 548

  Fly   350 AKSRPTF---HDATKKLTLL-----------LEKYEH 372
            ...||.|   |||...|:|.           ||..||
Frog   549 PDQRPDFPHLHDALTALSLFVGELGIPLPSELEYMEH 585

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
cdi	NP_524401.2	TyrKc	113..363	CDD:197581	115/274 (42%)
cdi	NP_524401.2	PKc_like	116..370	CDD:304357	118/289 (41%)
limk2	NP_001135686.1	LIM2_LIMK	62..115	CDD:188751
		STYKc	296..562	CDD:214568	114/271 (42%)
		STKc_LIMK2	299..568	CDD:271124	115/274 (42%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D119463at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.010