Protein Alignment CG6026 and Cngl

DIOPT Version :10

• Sequence 1: NP_650778.2
• Gene: CG6026 / 42287
• FlyBaseID: FBgn0038676
• Length: 1555
• Species: Drosophila melanogaster
• Sequence 2: NP_727848.3
• Gene: Cngl / 32468
• FlyBaseID: FBgn0263257
• Length: 1970
• Species: Drosophila melanogaster
• Alignment Length: 1327
• Identity: 237/1327 - (17%)
• Similarity: 410/1327 - (30%)
• Gaps: 432/1327 - (32%)

  Fly   371 DPADVYHTLGQKNTQA-----EEQQQLQLEKQQQMQKQQQIQHQQYQEQQQQQLYEQQQYQLQLE 430
            |..::..|||:|....     ::..:.|.:|:..........|  :|...|.|:::....:....
  Fly   691 DAQEILQTLGRKRLMEVRCVNKKYAKAQSDKEAAAYAAAHPHH--HQSHHQGQVHQSDSSENSAS 753

  Fly   431 KQHLDKQKHP---YQQQLEKQQQQQQQQQQQHHQQQHQQQHQQQQHQQHQQQHIQQQHQHQQQHQ 492
            |:.:||.||.   ::..|:|.:..::..:....|..|....:..:....:...::...:.....:
  Fly   754 KKIVDKLKHDVKGFRNVLKKSRTSRKSDESLEMQPLHNTSPRGSKILLKRMSRVRSDEKDADSAE 818

  Fly   493 PLPPTLQQQPSPPKPPMTLSDIFNSLAEEESNVAQNYQQ--NQGFDAQGNLIQPIAPSKPSPFAM 555
            .......:.|||....:.|......|.|::.::.:..::  ::||.    |||          .:
  Fly   819 AKDELHDKTPSPIGAGLPLLQRLRLLKEKQESIQEEPEREFSEGFP----LIQ----------RL 869

  Fly   556 QQPGTQQQPGTQQPAPHQRPSPNEQKVISGSQENYSNEYVS-YQVQQPNMMQYRPVPGQINNVVI 619
            ||...:.:|......|        ..|:..:..|.|::..| :...|.......|..|.|.  :.
  Fly   870 QQLKIKNEPQANAAEP--------GVVMVNTPPNISSKIDSHFAASQAGASHPGPNGGAIG--IS 924

  Fly   620 SPGQQSASFVLGSQVQQVSVGHPSIEKEPLFAKDTPGVQYGQVINEDIGNIKRPLKEPLPPPPNF 684
            :|||...       |.|:         :|:..     |.:.|.|
  Fly   925 APGQSLT-------VAQI---------KPIMK-----VSFKQKI--------------------- 947

  Fly   685 QQMPSIQQNSNFHQNGNVATSGAP----GTISYQEPP-----------PEAPTPYQQLPLIGSNK 734
            |||          |.|....|.:|    |.|:.:|||           .|.|.....|.| ||..
  Fly   948 QQM----------QGGGGGASSSPGPSTGAIAKKEPPKSLALVAKHATSEDPVAAAGLGL-GSGS 1001

  Fly   735 RPS----KKPVTKPEQPSHSY-PPQQSSTPQKPQPTPPVLMQGEDTKELLVSTNIRFPAQGEESL 794
            ...    .|.|.||:  ||.. .|.||.|.....|..|       ..:|.::|
  Fly  1002 SSGIATISKRVVKPQ--SHRMATPLQSDTDTDGTPIKP-------WSKLKLAT------------ 1045

  Fly   795 EPPSSAVMQGPPAGPNINGHAQPLSLQQIQNSNPVVFPKPMDEVVPGSASVQIQQHEVLNLSQQK 859
                  :|..              |...:.|.:|.....|            ::.:.:.|:.||
  Fly  1046 ------LMSS--------------SYTSLTNCSPDDLASP------------LKNYSLSNIPQQ- 1077

  Fly   860 QPLKFPAQQPGEQPSLEMEPPPRYPTTVPVAHAPPTPGKRPLGTSPPSNFYNEYNRKPQNGPRPS 924
                           :|....||:       |:..:..:.|.......:.:..:......|| .|
  Fly  1078 ---------------MESHTRPRH-------HSARSSSRSPRHGHHHHHHHGHHQHGQLQGP-SS 1119

  Fly   925 NLPNILPQFRPNAKISSGHPPALKQEPGNIRLP-----QQGGPGPKRPYNPA--MQPQFA----- 977
            ...|.....:.|...:|.....|:.:.....||     :.||.|.::.|...  :.|::.
  Fly  1120 TCTNGSTTSQVNQVTASAKRDCLRLQKPEQHLPDGELTELGGNGRRKLYQSVFDLSPEYCGLPFV 1184

  Fly   978 ------HRRQPLHQQHQQMMQKRYPMNRISEYPVGPGPGGDVNRRVYRLPPYGGQNVPYMPDHMY 1036
                  :.||.|.:..:.:..:.:.::....   ||.....:...:||.  |...:..|.
  Fly  1185 KRLKILNERQKLAELERALQTRSFSLDCSKS---GPDSKVPITESLYRC--YSDTSGIYS----- 1239

  Fly  1037 PRRPQGAGPLRSVDGYPAERHAPSSEPYKTIDAEAAAD-----FEEEDLVINDPPQPVTPGKDRK 1096
                      :.:..|.:...:.|.....:..|.|:|.     .:.....:...|.|::| :..:
  Fly  1240 ----------QFLSTYESTTSSTSISTNTSASASASASASASASDSNSRQLQYVPLPLSP-ESNE 1293

  Fly  1097 GTEETKLEPVV-TLQMLQSQKKAVSLPGDDTGAGEIQVTADNDPQEAEASKLSQQKLDPSGMYVV 1160
            ..|..||:.:: .|||...|::... ||..||||.:..|         .||::.
  Fly  1294 TMERRKLKSILKKLQMGGGQQEEAG-PGTGTGAGAVMGT---------GSKVNS----------- 1337

  Fly  1161 FPMKSAEKGQS-------EGDAPSAPAEYQNTPF-----------------------------SV 1189
               .:::|||.       ||  |.|.|:.:.:||                             ..
  Fly  1338 ---SASQKGQGLPAEPTLEG--PPASAKEEESPFGGAAAIGSVNNACGNGNGNGSVSGNGNGSGT 1397

  Fly  1190 IRDQPQEPILKNKKPQSLQQQNKAQHVPKD---KFPYPIEKPDPSFSELHPESQTSVSGVLVAPR 1251
            :.|..     .|.........|.|...|..   .||:|:.                     :||
  Fly  1398 VNDSS-----ANSSSHPSNNGNSAYTCPPPPSVAFPFPVP---------------------IAP- 1435

  Fly  1252 IITGAMGTGTETPIAIAYTPTEPNPFRHEQGQKFSNINLATSVINEIRQDTQTEEGLSSDFDLRG 1316
             .:|::....|..::..::||               :.|.|..       ...:|..:....|:|
  Fly  1436 -ASGSVPLPLEPGVSNVWSPT---------------LTLVTPT-------NSPQESFAFPAQLQG 1477

  Fly  1317 QNFEKDFMAPFYPSVSLGG-----------ASGAAAINPA-APSNWNILPSTTDQAIY------E 1363
            :               |||           .|.:|::.|| |.::.:...||:..|.|      .
  Fly  1478 E---------------LGGHGTGRGLVGGVGSASASMLPAGAGASASASASTSTSASYVVECSAS 1527

  Fly  1364 KNNINRADVETTEQKKPEEEQPTASALTAEKPSEMDSFQPQLQGGFKPIYPPGYKHVEQVEQEEI 1428
            .|.|..|...|......:..|.|.|::....|::.....|:.|..|..|. .|..||.:....|:
  Fly  1528 SNQILHAQSTTDLNLNLQLRQNTTSSMGGPGPAQRIEGFPEAQDYFNQIL-NGINHVIKTHMNEM 1591

  Fly  1429 AG------AKNAG----KDQPIA-LPLMGTTAKPSTSASPVSSSSSSSTSTSSTTSTTSTTHPPG 1482
            ..      :..||    :|..|| |.|...:.:..:||:|.|||||:..
  Fly  1592 HSKFETQFSSMAGEVRRRDAIIAQLQLKLRSIEGKSSAAPTSSSSSALV---------------- 1640

  Fly  1483 VTKSDVTLATTKAPAIST---KPTQRKKSTFETSLAALLFGDEDEED-----------GARKSAE 1533
               ..::....|.|.:|.   :|.:.:.::...|.|.|||...|..|           |.|.::.
  Fly  1641 ---LPISRRQKKMPQLSVDDDEPPEEEDNSSSGSSAELLFMRGDSLDTVFTSSPPIQGGRRSTSP 1702

  Fly  1534 LPK----AQVGPRNVPRM---GPRSLT 1553
            .|.    |.....|.|..   ||.||:
  Fly  1703 GPSRHHAASANALNCPSSYYGGPGSLS 1729

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6026	NP_650778.2	PHA03378	<792..975	CDD:223065	26/189 (14%)
Cngl	NP_727848.3	Ion_trans	240..509	CDD:459842
		CAP_ED	584..696	CDD:237999	1/4 (25%)
		dermokine	<1688..>1775	CDD:455732	10/42 (24%)