DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6013 and ccdc124

DIOPT Version :9

Sequence 1:	NP_650777.1	Gene:	CG6013 / 42286	FlyBaseID:	FBgn0038675	Length:	213	Species:	Drosophila melanogaster
Sequence 2:	NP_956859.1	Gene:	ccdc124 / 393537	ZFINID:	ZDB-GENE-040426-1483	Length:	216	Species:	Danio rerio

Alignment Length:	219	Identity:	104/219 - (47%)
Similarity:	138/219 - (63%)	Gaps:	19/219 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MPKK-MGINSKAVEARERKEATKKATQEKKSKEAEDRLWRDDDKNLAKKQQRKDEEERKRAEAAK 64
            |||| .|.|||:..||.||...|.....:|.||.||.||.|:||.:.||:||||::||||.||.:
Zfish     1 MPKKFQGENSKSATARARKAEAKAVADARKQKELEDALWEDNDKRVVKKEQRKDDKERKRLEALE 65

  Fly    65 RKAEAKALLDQEMSSI-NTQRKQPLAKINRQMILEEMEKKQRVIEAINEANKPMAARVVVQNH-- 126
            ||.|.:.||::|.|.| ..|.|:..:|:.|..|.|.::.||.|.| |.|..|         :|
Zfish    66 RKRENQRLLEEEDSKIKGKQTKEGPSKVTRAQIEETLQSKQNVKE-IKEKEK---------SHLD 120

  Fly   127 --IEENLNRSMAD--TDVASNIDEAIVVLSVNDSEEDKHPEKRMRAAYKTFEANNLPRIKAENPS 187
              :|||:||.:.:  |..|..|::||.|||..: :.|:|||:||:|||..||..|:||:|.|||:
Zfish   121 VPLEENVNRIVPEEGTVEARTIEDAIAVLSTKE-DLDRHPERRMKAAYTAFEEANMPRVKMENPN 184

  Fly   188 LRMSQWKQLLMKEWNKSPDNPFNQ 211
            :|:||.||.|.|||.|||:||.||
Zfish   185 MRLSQLKQQLKKEWTKSPENPLNQ 208

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6013	NP_650777.1	DUF1014	93..211	CDD:283823	56/123 (46%)
ccdc124	NP_956859.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..93		45/91 (49%)
		DUF1014	95..208	CDD:283823	56/123 (46%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	194..216		11/15 (73%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170582028
Domainoid	1	1.000	99	1.000	Domainoid score	I7069
eggNOG	1	0.900	-	-		E1_KOG3223
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H41702
Inparanoid	1	1.050	178	1.000	Inparanoid score	I4025
OMA	1	1.010	-	-		QHG54132
OrthoDB	1	1.010	-	-		D1585903at2759
OrthoFinder	1	1.000	-	-		FOG0005563
OrthoInspector	1	1.000	-	-		oto40100
orthoMCL	1	0.900	-	-		OOG6_102871
Panther	1	1.100	-	-	LDO	PTHR21680
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R173
SonicParanoid	1	1.000	-	-		X3982
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	17	16.800