DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6013 and Ccdc124

DIOPT Version :9

Sequence 1:	NP_650777.1	Gene:	CG6013 / 42286	FlyBaseID:	FBgn0038675	Length:	213	Species:	Drosophila melanogaster
Sequence 2:	NP_081240.1	Gene:	Ccdc124 / 234388	MGIID:	1916403	Length:	217	Species:	Mus musculus

Alignment Length:	217	Identity:	97/217 - (44%)
Similarity:	139/217 - (64%)	Gaps:	15/217 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MPKK-MGINSKAVEARERKEATKKATQEKKSKEAEDRLWRDDDKNLAKKQQRKDEEERKRAEAAK 64
            |||| .|.|||:..||.|:...|.|...||.||.||..|:|:||::.:|:|||:|:|::|.|..:
Mouse     1 MPKKFQGENSKSAAARARRAEAKAAADAKKQKELEDAYWKDEDKHVMRKEQRKEEKEKRRLEQLE 65

  Fly    65 RKAEAKALLDQEMSSI---NTQRKQPLAKINRQMILEEMEKKQRVIEAINEANKPMAARVVVQNH 126
            ||.|.:.||::|.|.:   ...|..| ||:.|..|.:.:.::||. |.:.:|...:      :..
Mouse    66 RKKETQRLLEEEDSRLKGGKAPRVAP-AKVTRAQIEDSLRREQRA-EPVEKAKSHL------ELP 122

  Fly   127 IEENLNRSMAD--TDVASNIDEAIVVLSVNDSEEDKHPEKRMRAAYKTFEANNLPRIKAENPSLR 189
            :||||||.:.:  :..|..:::||.||||.: |.|:|||:|||||:..||...|||:|.|||::|
Mouse   123 LEENLNRRLQEEGSVEARTVEDAIAVLSVAE-EADRHPERRMRAAFTAFEEVQLPRLKQENPNMR 186

  Fly   190 MSQWKQLLMKEWNKSPDNPFNQ 211
            :||.||||.|||.:|||||.||
Mouse   187 LSQLKQLLKKEWLRSPDNPMNQ 208

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6013	NP_650777.1	DUF1014	93..211	CDD:283823	53/119 (45%)
Ccdc124	NP_081240.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..120		48/126 (38%)
Ccdc124	NP_081240.1	Ccdc124	95..206	CDD:399330	52/118 (44%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167838184
Domainoid	1	1.000	103	1.000	Domainoid score	I6781
eggNOG	1	0.900	-	-		E1_KOG3223
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H41702
Inparanoid	1	1.050	170	1.000	Inparanoid score	I4127
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54132
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0005563
OrthoInspector	1	1.000	-	-		oto94035
orthoMCL	1	0.900	-	-		OOG6_102871
Panther	1	1.100	-	-	LDO	PTHR21680
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R173
SonicParanoid	1	1.000	-	-		X3982
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.790