DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Prp18 and AT1G54590

DIOPT Version :9

Sequence 1:	NP_650776.1	Gene:	Prp18 / 42285	FlyBaseID:	FBgn0027784	Length:	340	Species:	Drosophila melanogaster
Sequence 2:	NP_175861.2	Gene:	AT1G54590 / 841901	AraportID:	AT1G54590	Length:	361	Species:	Arabidopsis thaliana

Alignment Length:	320	Identity:	101/320 - (31%)
Similarity:	158/320 - (49%)	Gaps:	42/320 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 KKKYFRRGDLNAKNTEEV-LQKVGYIKQESVEAQGQTTEGAYSFVADGQNILPRTEVIRRLRERG 87
            |.:.||.|.|:.|:.... .|:|.: ::::...:|:.:...||::    :.:.|.:.::.:.:.|
plant    38 KTRDFRFGQLSRKDGNNFKSQRVTH-RRDTQPNRGRGSNLTYSWM----SFIVRLDRLKYVLKEG 97

  Fly    88 EPILIFGE-----TEPEAFDRLRQ-CEISQPEANRGFRNDFQEAMEQVDAAYLQEMFANTPTTKE 146
                :|.|     |:.|..|.||. .|:.:.|.:.|..||.:......|.....|        ||
plant    98 ----LFEEVDNDMTQGETNDFLRDITELKKRERSSGLMNDRKRKTSNDDELIGAE--------KE 150

  Fly   147 DKKSDFAELDESVSWESIQTMAANMGRNKDYDMDVIITLLTFLLKLWNDQIANYSKHEKMSTKVK 211
            |.|     |.|..::|.:            .|.|.|:.....||..|..::......|:.:...|
plant   151 DLK-----LLEEANFEDL------------CDEDKILVFCKKLLLEWKQELEAMENTERRTAIGK 198

  Fly   212 MTRVIYTQTKEYVKPLFRKLKHHTLPEDILDSLRDICKHLLNRNYITASDAYLEMAIGNAPWPIG 276
            .....:.|...|:.|||...::..||.||...|..:....:.|:|:.|:..::::||||||||||
plant   199 QMLATFNQCARYLTPLFHLCRNKCLPADIRQGLMVMVNCWIKRDYLDATAQFIKLAIGNAPWPIG 263

  Fly   277 VTMVGIHARTGREKI-FSKNVAHVMNDETQRKYIQGLKRLMTKCQEYFPTDPSKCVEYVS 335
            |||||||.|:.|||| .|.:|||:||:||.|||:|.:|||||.||..:...|||.:|:.|
plant   264 VTMVGIHERSAREKISTSSSVAHIMNNETTRKYLQSVKRLMTFCQRRYSALPSKSIEFNS 323

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prp18	NP_650776.1	SFM	74..117	CDD:128776	11/48 (23%)
Prp18	NP_650776.1	Prp18	186..322	CDD:280929	59/136 (43%)
AT1G54590	NP_175861.2	Prp18	172..310	CDD:280929	59/137 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	138	1.000	Domainoid score	I1569
eggNOG	1	0.900	-	-		E1_KOG2808
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	185	1.000	Inparanoid score	I1414
OMA	1	1.010	-	-		QHG54709
OrthoDB	1	1.010	-	-		D1485522at2759
OrthoFinder	1	1.000	-	-		FOG0004368
OrthoInspector	1	1.000	-	-		otm3420
orthoMCL	1	0.900	-	-		OOG6_102077
Panther	1	1.100	-	-	O	PTHR13007
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3091
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	14	13.840