DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Prp18 and AT1G03140

DIOPT Version :9

Sequence 1:	NP_650776.1	Gene:	Prp18 / 42285	FlyBaseID:	FBgn0027784	Length:	340	Species:	Drosophila melanogaster
Sequence 2:	NP_563676.1	Gene:	AT1G03140 / 839567	AraportID:	AT1G03140	Length:	420	Species:	Arabidopsis thaliana

Alignment Length:	392	Identity:	126/392 - (32%)
Similarity:	187/392 - (47%)	Gaps:	67/392 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MDILKAEIARKRKLLEQRQLVDEK--KKYFRRGDLNAKNTEEVLQKVGYIKQESVEAQGQTTEGA 63
            ||:|:.||.:|||     .|.:|.  ||:|:|.::..|.    :||:...::...|.:.|....|
plant     1 MDLLREEILKKRK-----SLAEESGGKKFFKRSEIEQKK----IQKLREEERREHELKAQRRAAA 56

  Fly    64 YSFVADGQN-------------------------------------ILPRTEVIRRLRERGEPIL 91
            .:...||::                                     ||||.|||||||...:|:.
plant    57 AASGGDGKSSGSAPGSSNAATSASSKSSASDAAAIADSKALTDENLILPRQEVIRRLRFLKQPMT 121

  Fly    92 IFGETEPEAFDRLRQC------EISQPEANRGFRNDFQEAMEQVDAAYLQEMFANTPTTKEDKKS 150
            :|||.:....|||:..      |:.. :...|..|||...:.::.......|..:......|::.
plant   122 LFGEDDQSRLDRLKYVLKEGLFEVDS-DMTEGQTNDFLRDIAELKKRQKSGMMGDRKRKSRDERG 185

  Fly   151 -DFAELDESVSWESIQTMAANMGRNKDY-----------DMDVIITLLTFLLKLWNDQIANYSKH 203
             |..:..|:...|.....::::..:||.           |.|.|:.....||..|..::......
plant   186 RDEGDRGETREDELSGGESSDVDADKDMKRLKANFEDLCDEDKILVFYKKLLIEWKQELDAMENT 250

  Fly   204 EKMSTKVKMTRVIYTQTKEYVKPLFRKLKHHTLPEDILDSLRDICKHLLNRNYITASDAYLEMAI 268
            |:.:.|.|.....:.|...|:.|||...:...||.||..:|..:..|.:.|:|:.|.|.|:::||
plant   251 ERRTAKGKQMVATFKQCARYLVPLFNLCRKKGLPADIRQALMVMVNHCIKRDYLAAMDHYIKLAI 315

  Fly   269 GNAPWPIGVTMVGIHARTGREKIFSKNVAHVMNDETQRKYIQGLKRLMTKCQEYFPTDPSKCVEY 333
            |||||||||||||||.|:.||||::.:|||:|||||.|||:|.:|||||.||..:||.|||.||:
plant   316 GNAPWPIGVTMVGIHERSAREKIYTNSVAHIMNDETTRKYLQSVKRLMTFCQRRYPTMPSKAVEF 380

  Fly   334 VS 335
            .|
plant   381 NS 382

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prp18	NP_650776.1	SFM	74..117	CDD:128776	18/48 (38%)
Prp18	NP_650776.1	Prp18	186..322	CDD:280929	63/135 (47%)
AT1G03140	NP_563676.1	SFM	104..148	CDD:128776	18/44 (41%)
AT1G03140	NP_563676.1	Prp18	232..369	CDD:397123	63/136 (46%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	138	1.000	Domainoid score	I1569
eggNOG	1	0.900	-	-		E1_KOG2808
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H2726
Inparanoid	1	1.050	185	1.000	Inparanoid score	I1414
OMA	1	1.010	-	-		QHG54709
OrthoDB	1	1.010	-	-		D1485522at2759
OrthoFinder	1	1.000	-	-		FOG0004368
OrthoInspector	1	1.000	-	-		otm3420
orthoMCL	1	0.900	-	-		OOG6_102077
Panther	1	1.100	-	-	LDO	PTHR13007
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3091
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	15	14.840