Protein Alignment Prp18 and prpf18

DIOPT Version :10

• Sequence 1: NP_650776.1
• Gene: Prp18 / 42285
• FlyBaseID: FBgn0027784
• Length: 340
• Species: Drosophila melanogaster
• Sequence 2: XP_021323304.1
• Gene: prpf18 / 431751
• ZFINID: ZDB-GENE-040704-45
• Length: 351
• Species: Danio rerio
• Alignment Length: 348
• Identity: 177/348 - (50%)
• Similarity: 235/348 - (67%)
• Gaps: 15/348 - (4%)

  Fly     1 MDILKAEIARKRKLLEQRQLVDEKKKYFRRGDLNAKNTEEVLQKVGY----------IKQESVEA 55
            ||||||||||||||:|:::|:|:.||||:|.:|..|..|:..::.||          :.:...||
Zfish     1 MDILKAEIARKRKLIEEKELIDDSKKYFKRAELARKEEEDYYRRCGYKVSNEQPVGQMDKPEEEA 65

  Fly    56 QGQTTEGAYSFVADGQNILP----RTEVIRRLRERGEPILIFGETEPEAFDRLRQCEISQPEANR 116
            ...|:......:...:..||    |.|||||||||||||.:|||::.:||.|||:.||..||.|:
Zfish    66 PQSTSANPVLELELTEEKLPMTLSRQEVIRRLRERGEPIRLFGESDYDAFQRLRKIEILAPEVNK 130

  Fly   117 GFRNDFQEAMEQVDAAYLQEMFANTPTTKEDKKSDFAELDESVSWESIQTMAANMGRNKDY-DMD 180
            |.|||.:.||:::|..||.|:.......:.|.:.|....:|:.:.|.::.:.|::|...|. |||
Zfish   131 GLRNDLKAAMDKIDQQYLNEIVGGAEGAELDTQHDLKVHEENTTIEELEALGASLGTGNDVRDMD 195

  Fly   181 VIITLLTFLLKLWNDQIANYSKHEKMSTKVKMTRVIYTQTKEYVKPLFRKLKHHTLPEDILDSLR 245
            :|..:|.|||.:|...:.:...|.|.|.:.|:......||:.|::||||||:...||.||.:|:.
Zfish   196 IINKVLRFLLGVWAKDLNSREDHIKRSVQGKLASATQKQTESYLEPLFRKLRKKNLPADIKESIT 260

  Fly   246 DICKHLLNRNYITASDAYLEMAIGNAPWPIGVTMVGIHARTGREKIFSKNVAHVMNDETQRKYIQ 310
            ||.|.:|.|.|:.|:||||:|||||||||||||||||||||||||||||:||||:||||||||||
Zfish   261 DIIKFMLEREYVKANDAYLQMAIGNAPWPIGVTMVGIHARTGREKIFSKHVAHVLNDETQRKYIQ 325

  Fly   311 GLKRLMTKCQEYFPTDPSKCVEY 333
            |||||||.||::|||||||||||
Zfish   326 GLKRLMTICQKHFPTDPSKCVEY 348

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prp18	NP_650776.1	SFM	74..117	CDD:128776	29/46 (63%)
		Prp18	184..324	CDD:460720	86/139 (62%)
prpf18	XP_021323304.1	SFM	88..131	CDD:128776	27/42 (64%)
		Prp18	201..339	CDD:460720	86/137 (63%)