Protein Alignment Prp18 and prp-18

DIOPT Version :10

• Sequence 1: NP_650776.1
• Gene: Prp18 / 42285
• FlyBaseID: FBgn0027784
• Length: 340
• Species: Drosophila melanogaster
• Sequence 2: NP_501776.2
• Gene: prp-18 / 177840
• WormBaseID: WBGene00009320
• Length: 352
• Species: Caenorhabditis elegans
• Alignment Length: 359
• Identity: 131/359 - (36%)
• Similarity: 197/359 - (54%)
• Gaps: 41/359 - (11%)

  Fly     4 LKAEIARKRKLLEQRQLVDEKKKYFRRGDLNAKNTEEVLQKVGYI--KQESV------EAQGQTT 60
            |.||:|:|||.:...::.:...|:.:..||..|..:|..:|...|  |:..|      |:..:|.
 Worm     7 LLAEMAKKRKAVSGMEVKEGNAKFVKGADLEMKRNQEYERKQQEIASKKRKVDDEILQESSSRTK 71

  Fly    61 EGAYSFVADGQNILPRTEVIRRLRERGEPILIFGETEPEAFDRLRQCEISQPEANRGFRNDFQEA 125
            .......::.....|.:|:..|||:|..||::||||:.:...||.|.|::||:.|.|:.|:.|.|
 Worm    72 PAPVENESEIDEKTPMSEIQTRLRQRNHPIMLFGETDIDVRKRLHQLELAQPDLNEGWENELQTA 136

  Fly   126 M----EQVDAAYLQEMFANTPTTKEDKKSDFA--ELDESVSWESIQTMAANMGRNKDY--DMDVI 182
            |    :::|.|.::      .|.....:.|.|  :..|..:|::|:..:..:..:.|.  |.|:|
 Worm   137 MKVIGKEMDKAVVE------GTADSATRHDIALPQGYEEDNWKNIEHNSTLLSVDDDLKRDCDII 195

  Fly   183 ITLLTFLLKLW----NDQIANYSK-----HEKMSTKVKMTRVIYTQTKEYVKPLFRKLKHHTLPE 238
            :::..::|..|    ||:..:..|     ||....|         ||..::|.|...::.:....
 Worm   196 LSICRYILARWAKDLNDRPLDVKKTAQGMHEAAHHK---------QTMMHLKSLMTSMERYNCNN 251

  Fly   239 DILDSLRDICKHL-LNRNYITASDAYLEMAIGNAPWPIGVTMVGIHARTGREKIFSKNVAHVMND 302
            ||...|..||:.| ::|||:.|::||:||||||||||:|||..|||.|.|..|.:..|:|||:||
 Worm   252 DIRHHLAKICRLLVIDRNYLEANNAYMEMAIGNAPWPVGVTRSGIHQRPGSAKSYVSNIAHVLND 316

  Fly   303 ETQRKYIQGLKRLMTKCQEYFPTDPSKCVEYVSK 336
            ||||||||..||||||.||||||||||.||:|.|
 Worm   317 ETQRKYIQAFKRLMTKMQEYFPTDPSKSVEFVKK 350

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prp18	NP_650776.1	SFM	74..117	CDD:128776	19/42 (45%)
		Prp18	184..324	CDD:460720	66/149 (44%)
prp-18	NP_501776.2	SFM	85..128	CDD:128776	19/42 (45%)
		Prp18	196..338	CDD:460720	66/150 (44%)