DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GatA and faah2a

DIOPT Version :9

Sequence 1:	NP_650775.2	Gene:	GatA / 42283	FlyBaseID:	FBgn0260779	Length:	508	Species:	Drosophila melanogaster
Sequence 2:	NP_001002700.1	Gene:	faah2a / 436973	ZFINID:	ZDB-GENE-040718-453	Length:	532	Species:	Danio rerio

Alignment Length:	497	Identity:	124/497 - (24%)
Similarity:	199/497 - (40%)	Gaps:	109/497 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 LNAFVRLTPEQAGQQAQDAEQRYKL-------------RQPISDLDGVTIAIKDNFCTKDVHTTC 91
            :||.|:   ::.....|:|.|..||             |.|   |.||.|.:|:.|..:.:..:.
Zfish    83 INAMVK---DRFSAALQEAAQVDKLIEEETGGEDVLEDRLP---LLGVPITVKEAFALQGMPNST 141

  Fly    92 ASRMLQDFVPPYDATVCSRLKQAGAVILGKTNMDQFAMGAGTVDSLYGPTKNIWSEDLNKDHWRI 156
            .....:|.|...||...:.||:|||:.||.||..:..|...:.:.|||.|.|.:      |..||
Zfish   142 GLLTRRDLVSGADAPSVALLKRAGAIPLGVTNCSELCMWLESHNHLYGITNNPY------DFERI 200

  Fly   157 AGGSSGGSASAVAAGLCYAAIGSDTGGSTRNPASYCGVVGLKPTYGLVSRHGLIPLVNSMDV--- 218
            .||||||..|.:.||.....||||.|||.|.|..:.|:.|.||:.|:|:..|..|..:...:
Zfish   201 VGGSSGGEGSILGAGSSVIGIGSDIGGSIRIPCFFNGIFGHKPSVGIVNNEGQYPPASGQQMGFL 265

  Fly   219 -PGIFARSVSDCVAVLNTVAGP--DKLDSTTIRQPFTRLHLPEVGQIDLSTVR-IGIPKEYHCHG 279
             .|...|...|.:.:|:.:.||  :||...|              ::||..:| ..:|.....|.
Zfish   266 CTGPMCRYAEDLIPMLSIMGGPNAEKLSLFT--------------EVDLKKLRFFSVPHNGGSHL 316

  Fly   280 LS---AEVLETWSKVADLLECS-GASVRQVSLPNTAASIFVYTILNQCEVASNMARYDGIEYGHR 340
            :|   .::|.....|...||.. |..|:::.:|....|..::..:    :||  ...||
Zfish   317 VSPVEPQLLHAQKMVVKRLEADLGVKVQELLIPQLKYSFQIWGTM----MAS--PGKDG------ 369

  Fly   341 ATDERSTEQLYALSRAEGFNDVVKTRILTGNFL----------------LLKKNYDHYFEKALRV 389
                 .....:|...:||...|.....|...||                |.:.::...|  .::.
Zfish   370 -----KPPTTFAELMSEGGKKVWPAWELFKWFLGFSSHTLAAIGLALVELFQSSHPSPF--IMQQ 427

  Fly   390 RRLIAEDFARVFDSSAKEERVDILLTPTTLTEA-----PLYKDFASLTNRDQCAVQDFC-TQPAN 448
            :..:.::...:..:..      :||.|:....|     |::..|            :|. |...|
Zfish   428 KESLQQELEELLGTDG------VLLYPSHPLIAQKHHHPIFTPF------------NFSYTGIFN 474

  Fly   449 MAGIPAVSIPIRLSQAGLPLSLQLMSNSLNEQLLLTVARWIE 490
            :.|:|....|:.||..||||.:|:::..|.::|.|..|.::|
Zfish   475 ILGLPVTQCPLGLSAEGLPLGVQIVAGKLQDRLSLATALYLE 516

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GatA	NP_650775.2	PRK07488	8..491	CDD:236030	124/497 (25%)
GatA	NP_650775.2	gatA	18..490	CDD:234572	123/495 (25%)
faah2a	NP_001002700.1	PRK07488	46..526	CDD:236030	124/497 (25%)
faah2a	NP_001002700.1	Amidase	48..525	CDD:302749	124/497 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0154
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810