DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment GatA and qrsl1

DIOPT Version :9

Sequence 1:	NP_650775.2	Gene:	GatA / 42283	FlyBaseID:	FBgn0260779	Length:	508	Species:	Drosophila melanogaster
Sequence 2:	NP_001112370.1	Gene:	qrsl1 / 327329	ZFINID:	ZDB-GENE-030131-5540	Length:	536	Species:	Danio rerio

Alignment Length:	518	Identity:	261/518 - (50%)
Similarity:	356/518 - (68%)	Gaps:	25/518 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 SIKQLTASYSDGQLSPRRVTEDALQDALRWKTLNAFVRLTPEQAGQQAQDAEQRYKLRQPISDLD 72
            ||::::.:..||::|...:....:....|.:.|||::.:..|.|.:||:.|::|.:..:.:..||
Zfish    18 SIREVSQALRDGKVSATELCRKCINQIQRTRYLNAYITIAEETAMEQAERADKRLRTGKTLGPLD 82

  Fly    73 GVTIAIKDNFCTKDVHTTCASRMLQDFVPPYDATVCSRLKQAGAVILGKTNMDQFAMGAGTVDSL 137
            |:..::||||||:::.|||||.||:.:|||:.|||..:|...|||::||||:|:||||||:.|..
Zfish    83 GIPFSVKDNFCTENIKTTCASNMLKGYVPPFSATVVQKLLDQGAVLVGKTNLDEFAMGAGSTDGA 147

  Fly   138 YGPTKNIWS----------EDLNKDHWRIAGGSSGGSASAVAAGLCYAAIGSDTGGSTRNPASYC 192
            :||.:|.||          ||.:.| |.|.||||||||:|||:...:.|:|||||||||||.|.|
Zfish   148 FGPVRNPWSYAAPYREQSAEDPDSD-WTITGGSSGGSAAAVASLSSFLALGSDTGGSTRNPGSLC 211

  Fly   193 GVVGLKPTYGLVSRHGLIPLVNSMDVPGIFARSVSDCVAVLNTVAGPDKLDSTTIRQPFTRLHLP 257
            |||.|||:|||:|||||||||||||||||..|||.|...||..:.|.|:.||||::.|.|...||
Zfish   212 GVVALKPSYGLLSRHGLIPLVNSMDVPGIMTRSVHDAATVLRILQGRDERDSTTVQAPNTPPSLP 276

  Fly   258 EVGQIDLSTVRIGIPKEYHCHGLSAEVLETWSKVADLLECSGASVRQVSLPNTAASIFVYTILNQ 322
            |  ..|:..:.:|||||||..|||.:.|..||:|||:.|.:||.|::||||:|..||..|.:|..
Zfish   277 E--HFDMRKICVGIPKEYHAPGLSEDTLAQWSRVADIFENAGARVKEVSLPHTPYSIVCYHVLCC 339

  Fly   323 CEVASNMARYDGIEYGHRATDERSTEQLYALSRAEGFNDVVKTRILTGNFLLLKKNYDHYFEKAL 387
            |||||||||:||:|||||:..:.||:.:||.:|.||||:||:.|||:||:.|||.||:.||.||.
Zfish   340 CEVASNMARFDGLEYGHRSAVDSSTDAMYATTRHEGFNNVVRRRILSGNYFLLKSNYERYFVKAQ 404

  Fly   388 RVRRLIAEDFARVFDSSAKEERVDILLTPTTLTEAPLYKDFASLTNRDQCAVQDFCTQPANMAGI 452
            ::||||||||.:||.|.     :|:|||||||::|..|.||.:..||.:.|.:|..|||.||||:
Zfish   405 QMRRLIAEDFKKVFSSG-----IDVLLTPTTLSDAARYADFITEDNRTRSAQEDVFTQPVNMAGL 464

  Fly   453 PAVSIPIRLSQAGLPLSLQLMSNSLNEQLLLTVARWIEAQVEF-------DSLEHSQQYKASL 508
            |||::|..|||.|||:.|||:..:|.:..|||:|.|:|.|:.|       |..|:.::...|:
Zfish   465 PAVTVPTALSQRGLPIGLQLIGQTLQDWKLLTIAHWMEKQLHFPMIRFHRDLNENEREQNRSI 527

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GatA	NP_650775.2	PRK07488	8..491	CDD:236030	255/492 (52%)
GatA	NP_650775.2	gatA	18..490	CDD:234572	253/481 (53%)
qrsl1	NP_001112370.1	PRK07488	17..505	CDD:236030	256/494 (52%)
qrsl1	NP_001112370.1	gatA	26..502	CDD:234572	253/483 (52%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170586404
Domainoid	1	1.000	487	1.000	Domainoid score	I377
eggNOG	1	0.900	-	-		E1_COG0154
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6699
Inparanoid	1	1.050	513	1.000	Inparanoid score	I1272
OMA	1	1.010	-	-		QHG60965
OrthoDB	1	1.010	-	-		D1195292at2759
OrthoFinder	1	1.000	-	-		FOG0004263
OrthoInspector	1	1.000	-	-		oto40272
orthoMCL	1	0.900	-	-		OOG6_101205
Panther	1	1.100	-	-	LDO	PTHR11895
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R473
SonicParanoid	1	1.000	-	-		X3001
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	16	15.800