DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment GatA and Qrsl1

DIOPT Version :9

Sequence 1:	NP_650775.2	Gene:	GatA / 42283	FlyBaseID:	FBgn0260779	Length:	508	Species:	Drosophila melanogaster
Sequence 2:	NP_001014056.1	Gene:	Qrsl1 / 309911	RGDID:	1359490	Length:	525	Species:	Rattus norvegicus

Alignment Length:	504	Identity:	266/504 - (52%)
Similarity:	350/504 - (69%)	Gaps:	19/504 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 SIKQLTASYSDGQLSPRRVTEDALQDALRWKTLNAFVRLTPEQAGQQAQDAEQRYKLRQPISDLD 72
            ::::::::...|.::|..:.:..|....:.|.|||::.::.|.|.:||:::|:|||..|.:.|||
  Rat     5 TLREVSSALKQGHITPTELCKKCLSLIKKTKYLNAYITVSEEVALKQAEESEKRYKQGQSLGDLD 69

  Fly    73 GVTIAIKDNFCTKDVHTTCASRMLQDFVPPYDATVCSRLKQAGAVILGKTNMDQFAMGAGTVDSL 137
            |:.:|:||||.|..:.|||||.||:.::|||:|||..||...||:::||||:|:||||:|:.|.:
  Rat    70 GIPVAVKDNFSTSGIETTCASNMLKGYLPPYNATVVQRLLDQGALLMGKTNLDEFAMGSGSTDGV 134

  Fly   138 YGPTKNIWS----------EDLNKD-HWRIAGGSSGGSASAVAAGLCYAAIGSDTGGSTRNPASY 191
            :||.||.|:          :|..:| ||.|.||||||||:||||..|:||:||||||||||||::
  Rat   135 FGPVKNPWTYSKQYRERSRQDAQEDSHWLITGGSSGGSAAAVAAFTCFAALGSDTGGSTRNPAAH 199

  Fly   192 CGVVGLKPTYGLVSRHGLIPLVNSMDVPGIFARSVSDCVAVLNTVAGPDKLDSTTIRQPFTRLHL 256
            ||.||.||:||||||||||||||||||||||.|.|.|...||..:||.|..||||:..|.....|
  Rat   200 CGTVGFKPSYGLVSRHGLIPLVNSMDVPGIFTRCVDDTAIVLGVLAGHDPKDSTTVNDPVKPTTL 264

  Fly   257 PEVGQIDLSTVRIGIPKEYHCHGLSAEVLETWSKVADLLECSGASVRQVSLPNTAASIFVYTILN 321
            |.|.  |:|.:.|||||||....||:|:...||:.|||.|..||.|.:|.||:|..||..|.:|.
  Rat   265 PSVP--DVSGLCIGIPKEYLVPELSSEIRSLWSQAADLFEAEGARVIEVCLPHTCYSIVCYHVLC 327

  Fly   322 QCEVASNMARYDGIEYGHR-ATDERSTEQLYALSRAEGFNDVVKTRILTGNFLLLKKNYDHYFEK 385
            ..||||||||:||::|||| |.|..|||.|||.:|.||||||||.|||:|||.|||:||::||.|
  Rat   328 TSEVASNMARFDGLQYGHRSAVDMSSTEALYAATRQEGFNDVVKGRILSGNFFLLKENYENYFVK 392

  Fly   386 ALRVRRLIAEDFARVFDSSAKEERVDILLTPTTLTEAPLYKDFASLTNRDQCAVQDFCTQPANMA 450
            |.:|||||..||..||.|.     ||:||||||||:|..|.:|....||.:.|..|..||..|||
  Rat   393 AQKVRRLIVNDFVNVFGSG-----VDVLLTPTTLTQAVPYLEFIKEDNRTRSAQDDIFTQAVNMA 452

  Fly   451 GIPAVSIPIRLSQAGLPLSLQLMSNSLNEQLLLTVARWIEAQVEFDSLE 499
            |:|||::|:.||..|||:.|||:..:..:|.|||||:|.|.||:|..::
  Rat   453 GLPAVNVPVALSSQGLPIGLQLIGRAFCDQQLLTVAKWFEKQVQFPVIQ 501

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GatA	NP_650775.2	PRK07488	8..491	CDD:236030	262/494 (53%)
GatA	NP_650775.2	gatA	18..490	CDD:234572	262/483 (54%)
Qrsl1	NP_001014056.1	PRK07488	5..493	CDD:236030	262/494 (53%)
Qrsl1	NP_001014056.1	gatA	13..492	CDD:234572	262/485 (54%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166345359
Domainoid	1	1.000	489	1.000	Domainoid score	I364
eggNOG	1	0.900	-	-		E1_COG0154
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6699
Inparanoid	1	1.050	517	1.000	Inparanoid score	I1240
OMA	1	1.010	-	-		QHG60965
OrthoDB	1	1.010	-	-		D1195292at2759
OrthoFinder	1	1.000	-	-		FOG0004263
OrthoInspector	1	1.000	-	-		oto98706
orthoMCL	1	0.900	-	-		OOG6_101205
Panther	1	1.100	-	-	LDO	PTHR11895
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3001
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.770