DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GatA and SPBC646.03

DIOPT Version :9

Sequence 1:	NP_650775.2	Gene:	GatA / 42283	FlyBaseID:	FBgn0260779	Length:	508	Species:	Drosophila melanogaster
Sequence 2:	NP_595361.1	Gene:	SPBC646.03 / 2541102	PomBaseID:	SPBC646.03	Length:	471	Species:	Schizosaccharomyces pombe

Alignment Length:	418	Identity:	160/418 - (38%)
Similarity:	245/418 - (58%)	Gaps:	18/418 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    76 IAIKDNFCTKDVHTTCASRMLQDFVPPYDATVCSRLKQAGAVILGKTNMDQFAMGAGTVDSLYGP 140
            |.:|:|.|||...||.||.||:|:..|:||::...||:||.:||||||||:||||..:.::|:|.
pombe    61 ITVKENICTKTNLTTAASNMLKDYNSPFDASIVESLKKAGGIILGKTNMDEFAMGVKSENNLFGR 125

  Fly   141 TKNIWSEDLNKDHWRIAGGSSGGSASAVAAGLCYAAIGSDTGGSTRNPASYCGVVGLKPTYGLVS 205
            |.|...:|.|.|    .||||||:|:|:||.:|||::|||||||.|.||:|.|.||.||::|.:|
pombe   126 TVNPVVKDSNYD----VGGSSGGAAAAIAADICYASVGSDTGGSIRLPAAYVGCVGFKPSFGRIS 186

  Fly   206 RHGLIPLVNSMDVPGIFARSVSDCVAVLNTVAGPDKLDSTTIRQPFTRLHLPEVGQIDLSTVRIG 270
            |:|::...||.|..||.|.:|.....|.|.:..||..|||.:.:........:..::....::||
pombe   187 RYGMLAFANSFDTVGIAANNVKGVTKVFNVLDHPDINDSTCLTKEARYFVKEQHKKLSRKPIKIG 251

  Fly   271 IPKEYHCHGLSAEVLETWSKVADLLECSGASVRQVSLPNTAASIFVYTILNQCEVASNMARYDGI 335
            ||.:::.......||:.|::...||:.:|..|:::.||.:..:..||:.:...|..||:|:|:.|
pombe   252 IPIDWNVSETHPNVLDKWNEFISLLKSNGYLVQEIQLPISLYANSVYSTMAYAEATSNLAKYNTI 316

  Fly   336 EYGHRATDERSTEQLYALSRAEGF--NDVVKTRILTGNFLLLKKNYDHYFEKALRVRRLIAEDFA 398
            .:|: ..||:..|::.: |.|..|  .|.||.|:|.|.:.|.:.|....|.||..|||.|..:|.
pombe   317 AFGN-CLDEKFEEEIIS-STARSFFLGDEVKKRLLLGAYSLARMNSSDLFSKARYVRRAIQLEFN 379

  Fly   399 RVF---DSSAKEER--VDILLTPTTLTEAPLYKDFASLTNRDQCAVQDFCTQPANMAGIPAVSIP 458
            :.|   ..|..:.|  :|.::||:....:...:..:|.::     :.|....||||||||:||||
pombe   380 KNFFLPSFSVDDPRGDIDFIVTPSFFNSSQPIETPSSYSH-----LSDTMLVPANMAGIPSVSIP 439

  Fly   459 IRLSQAGLPLSLQLMSNSLNEQLLLTVA 486
            ......|||:.:|:|:..||::.||:.|
pombe   440 FGTLNNGLPMGIQIMAQYLNDEDLLSFA 467

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GatA	NP_650775.2	PRK07488	8..491	CDD:236030	160/418 (38%)
GatA	NP_650775.2	gatA	18..490	CDD:234572	160/418 (38%)
SPBC646.03	NP_595361.1	Amidase	12..470	CDD:302749	160/418 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	271	1.000	Domainoid score	I329
eggNOG	1	0.900	-	-		E1_COG0154
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6699
Inparanoid	1	1.050	272	1.000	Inparanoid score	I701
OMA	1	1.010	-	-		QHG60965
OrthoFinder	1	1.000	-	-		FOG0004263
OrthoInspector	1	1.000	-	-		oto102076
orthoMCL	1	0.900	-	-		OOG6_101205
Panther	1	1.100	-	-	LDO	PTHR11895
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R473
SonicParanoid	1	1.000	-	-		X3001
TreeFam	1	0.960	-	-
	14	13.860