DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GatA and Y41D4A.6

DIOPT Version :9

Sequence 1:	NP_650775.2	Gene:	GatA / 42283	FlyBaseID:	FBgn0260779	Length:	508	Species:	Drosophila melanogaster
Sequence 2:	NP_001294547.1	Gene:	Y41D4A.6 / 176982	WormBaseID:	WBGene00021508	Length:	454	Species:	Caenorhabditis elegans

Alignment Length:	472	Identity:	191/472 - (40%)
Similarity:	292/472 - (61%)	Gaps:	30/472 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 EDALQDALRWKTLNAFVRLTPEQAGQQAQDAEQRYKLRQPISDLDGVTIAIKDNFCTKDVHTTCA 92
            |.:::.|:::::...|:..|.|.|.|||::|.:        :.|:...||:||.|.|....||||
Worm     5 ESSIEKAVKYRSHGIFITETFELARQQAKNALK--------NGLNPFPIAVKDCFLTNGTSTTCA 61

  Fly    93 SRMLQDFVPPYDATVCSRLKQAGAVILGKTNMDQFAMGAGTVDSLYGPTKNIWSEDLNKDHWRIA 157
            |:||:.:.||.:||:..|:...|..|:||||:|:|.||..:....:||.|:..:|....:.|.|.
Worm    62 SQMLEKYTPPVNATIVERIVARGGCIIGKTNLDEFCMGTSSALGHFGPVKSDLTEPGGTEDWTIP 126

  Fly   158 GGSSGGSASAVAAGLCYAAIGSDTGGSTRNPASYCGVVGLKPTYGLVSRHGLIPLVNSMDVPGIF 222
            ||||||||.||..|:...|:||||||||||||::.|:.|.|||||::||:||||||||:|.|.||
Worm   127 GGSSGGSAVAVQTGIADFALGSDTGGSTRNPAAFNGIFGFKPTYGVLSRNGLIPLVNSLDAPSIF 191

  Fly   223 ARSVSDCVAVLNTVAGPDKLDSTTIRQPFTRLHLPE-VGQIDLSTVRIGIPKEYHCHGLSAEVLE 286
            |::...|..:|....|.||.|||::       .||| .|...|..::||||.|||...|:.:...
Worm   192 AKTAQKCWELLELSKGIDKNDSTSV-------ELPEKAGISSLEGLKIGIPVEYHNECLTEDAWR 249

  Fly   287 TWSKVADLLECSGAS-VRQVSLPNTAASIFVYTILNQCEVASNMARYDGIEYGHRATDERSTEQL 350
            .|::|..||:..||: :..::||.|..|:..|:::...:|||||||||.:.||||::.:.||.::
Worm   250 HWNRVTGLLKSRGAAEIHVLNLPTTRFSLACYSVIAAADVASNMARYDSVAYGHRSSSDSSTYEM 314

  Fly   351 YALSRAEGFNDVVKTRILTGNFLLLKK-NY-DHYFEKALRVRRLIAEDFARVFDSSAKEERVDIL 413
            ||.||:|..|.:|:.||..||:.|:|: .| ..|||:||:|||:|.::..:.|      ..||::
Worm   315 YASSRSEALNTIVRRRIFAGNYFLMKQWGYRQKYFERALKVRRIIHDELRQAF------REVDLI 373

  Fly   414 LTPTTLTEAPLYKDFAS--LTNRDQCAVQDFCTQPANMAGIPAVSIPIRLSQAGLPLSLQLMSNS 476
            :|||....||.|.:...  .:..|.   .|:.||.||:||||::|:|:.:::.|||:.:|||::.
Worm   374 VTPTASGTAPKYSELRDTLFSKEDN---DDYFTQAANLAGIPSISVPVGVAEDGLPIGVQLMADK 435

  Fly   477 LNEQLLLTVARWIEAQV 493
            |.::.:..||..::..:
Worm   436 LQDRAVCDVAHILDGLI 452

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GatA	NP_650775.2	PRK07488	8..491	CDD:236030	191/468 (41%)
GatA	NP_650775.2	gatA	18..490	CDD:234572	191/467 (41%)
Y41D4A.6	NP_001294547.1	gatA	20..448	CDD:234572	189/451 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160162204
Domainoid	1	1.000	342	1.000	Domainoid score	I573
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6699
Inparanoid	1	1.050	352	1.000	Inparanoid score	I1332
Isobase	1	0.950	-	0.729574	Normalized mean entropy	S1380
OMA	1	1.010	-	-		QHG60965
OrthoDB	1	1.010	-	-		D1195292at2759
OrthoFinder	1	1.000	-	-		FOG0004263
OrthoInspector	1	1.000	-	-		oto19515
orthoMCL	1	0.900	-	-		OOG6_101205
Panther	1	1.100	-	-	LDO	PTHR11895
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R473
SonicParanoid	1	1.000	-	-		X3001
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	17	16.850