DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment snRNP-U1-C and SNRPC

DIOPT Version :9

Sequence 1:	NP_650767.1	Gene:	snRNP-U1-C / 42274	FlyBaseID:	FBgn0261792	Length:	145	Species:	Drosophila melanogaster
Sequence 2:	NP_003084.1	Gene:	SNRPC / 6631	HGNCID:	11157	Length:	159	Species:	Homo sapiens

Alignment Length:	153	Identity:	92/153 - (60%)
Similarity:	106/153 - (69%)	Gaps:	26/153 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MPKYYCDYCDTYLTHDSPSVRKTHCTGRKHRDNVKFYYQKWMEEQAQHLIDATTAAFKAGKITNN 65
            |||:|||||||||||||||||||||:||||::|||.|||||||||||.|||.|||||:.|||...
Human     1 MPKFYCDYCDTYLTHDSPSVRKTHCSGRKHKENVKDYYQKWMEEQAQSLIDKTTAAFQQGKIPPT 65

  Fly    66 PFAGGPGGAPPKPAGVSI-PPPNMGAPPRPGMPGMPYM--PPLMNPMMGMRPPPIMNPMAMMGPP 127
            ||:     ||| |||..| |||::..||||||...|:|  ||:| ||||..||.:|
Human    66 PFS-----APP-PAGAMIPPPPSLPGPPRPGMMPAPHMGGPPMM-PMMGPPPPGMM--------- 114

  Fly   128 PPLGTIPGVRP------GIMNGP 144
             |:|..||:||      .:|.||
Human   115 -PVGPAPGMRPPMGGHMPMMPGP 136

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
snRNP-U1-C	NP_650767.1	zf-U1	1..38	CDD:368798	31/36 (86%)
SNRPC	NP_003084.1	zf-U1	1..38	CDD:368798	31/36 (86%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	62..96		19/39 (49%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	140..159
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	92	1.000	Domainoid score	I7637
eggNOG	1	0.900	-	-		E1_COG5136
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	171	1.000	Inparanoid score	I4110
Isobase	1	0.950	-	0	Normalized mean entropy	S740
OMA	1	1.010	-	-		QHG53368
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003605
OrthoInspector	1	1.000	-	-		oto90337
orthoMCL	1	0.900	-	-		OOG6_102948
Panther	1	1.100	-	-	LDO	PTHR31148
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1268
SonicParanoid	1	1.000	-	-		X2482
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	14	13.810