DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dnk and Dguok

DIOPT Version :9

Sequence 1:	NP_001262722.1	Gene:	dnk / 42273	FlyBaseID:	FBgn0022338	Length:	250	Species:	Drosophila melanogaster
Sequence 2:	NP_038792.2	Gene:	Dguok / 27369	MGIID:	1351602	Length:	277	Species:	Mus musculus

Alignment Length:	218	Identity:	75/218 - (34%)
Similarity:	115/218 - (52%)	Gaps:	27/218 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 EGTQPFTVLIEGNIGSGKTTYLNHFEKYKNDICLLTEPVEKWRNVNGV------------NLLEL 68
            :|..|..:.|||||..||:|::....|...:..:.|||:.:|:|:...            ||||:
Mouse    34 DGGGPRRLCIEGNIAVGKSTFVKLLMKTHPEWQVATEPIAEWQNIQAAGAQKDGTSKRLGNLLEM 98

  Fly    69 MYKDPKKWAMPFQSYVTLTMLQSHTAP-------TNKKLKIMERSIFSARYCFVENMRRNGSLEQ 126
            ||::|.:|:..||:...::.|:....|       ..|.:::.|||::|.||.|.:|:..||||..
Mouse    99 MYQEPARWSYTFQTLSFMSRLKVQLEPIPGRLLQAEKSVRVFERSVYSDRYIFAKNLFENGSLSD 163

  Fly   127 GMYNTLEEWYKFIEESIHVQADL--IIYLRTSPEVAYERIRQRARSEESCVPLKYLQELHELHED 189
            ..::..::|:.|:.:....:..|  .|||:.||:|..||:.||.|.||..:.|.|||:||..|||
Mouse   164 IEWHIYQDWHSFLLQEFANRLLLHGFIYLQASPQVCMERLYQRDREEEKGIELAYLQQLHSQHED 228

  Fly   190 WLI------HQRRPQSCKVLVLD 206
            |.|      |....|...|||||
Mouse   229 WFINKTTKLHFEALQHVPVLVLD 251

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dnk	NP_001262722.1	dNK	23..214	CDD:238836	73/211 (35%)
dnk	NP_001262722.1	DTMP_kinase	23..214	CDD:161676	73/211 (35%)
Dguok	NP_038792.2	dNK	41..275	CDD:279974	73/211 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1428
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54257
OrthoDB	1	1.010	-	-		D1505356at2759
OrthoFinder	1	1.000	-	-		FOG0001503
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_102194
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.730