Protein Alignment Smu1 and SEC12

DIOPT Version :10

• Sequence 1: NP_650766.1
• Gene: Smu1 / 42272
• FlyBaseID: FBgn0038666
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: NP_014423.1
• Gene: SEC12 / 855760
• SGDID: S000005309
• Length: 471
• Species: Saccharomyces cerevisiae
• Alignment Length: 215
• Identity: 57/215 - (26%)
• Similarity: 95/215 - (44%)
• Gaps: 26/215 - (12%)

  Fly   202 PTQLFRQIKFGQKSHVECAQFSPDGQYL--ITGSVDGFLEVWNFTTGK--VRK---DLKYQ-AQD 258
            |:.|..:.:...:..|:...||.||:.:  ||||   .|||.:..||.  .||   |..:. ::.
Yeast   161 PSDLTEKFEIETRGEVKDLHFSTDGKVVAYITGS---SLEVISTVTGSCIARKTDFDKNWSLSKI 222

  Fly   259 QFMMMEQAVLALNFSRDSEMVAS--GAQDGQIKVWRIITGQCLRKFEKAHTKGITCLQFSRDNSQ 321
            .|:..:..::|.:..:...:|.:  ..:.|...|.|  :.|...:|     ||||.:........
Yeast   223 NFIADDTVLIAASLKKGKGIVLTKISIKSGNTSVLR--SKQVTNRF-----KGITSMDVDMKGEL 280

  Fly   322 VLSASFDYTVRLHGLKSGKMLKEFK-GHSSFVNEATFTPDGHSVLSASSDGTVKVWSLKTTECVA 385
            .:.||.|.::.|..||...|.|.|| .||..:.|.|.:||...|.|.|:..|:.:  :|.....|
Yeast   281 AVLASNDNSIALVKLKDLSMSKIFKQAHSFAITEVTISPDSTYVASVSAANTIHI--IKLPLNYA 343

  Fly   386 TYKPLGNELA---VNTVLIL 402
            .|..:..:::   .|.:||:
Yeast   344 NYTSMKQKISKFFTNFILIV 363

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Smu1	NP_650766.1	LisH_TPL	7..36	CDD:375350
		CTLH	40..90	CDD:128914
		WD40	<203..509	CDD:441893	56/214 (26%)
		WD40 repeat	218..256	CDD:293791	16/45 (36%)
		WD40 repeat	267..303	CDD:293791	6/37 (16%)
		WD40 repeat	311..346	CDD:293791	9/34 (26%)
		WD40 repeat	352..432	CDD:293791	14/54 (26%)
		WD40 repeat	440..477	CDD:293791
		WD40 repeat	483..507	CDD:293791
SEC12	NP_014423.1	WD40	<138..335	CDD:441893	51/183 (28%)
		WD40 repeat	177..212	CDD:293791	15/37 (41%)
		WD40 repeat	219..258	CDD:293791	5/38 (13%)
		WD40 repeat	270..305	CDD:293791	9/34 (26%)
		WD40 repeat	312..360	CDD:293791	12/49 (24%)
		WD40 repeat	368..431	CDD:293791