Protein Alignment Smu1 and smu1

DIOPT Version :10

• Sequence 1: NP_650766.1
• Gene: Smu1 / 42272
• FlyBaseID: FBgn0038666
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: NP_989188.1
• Gene: smu1 / 394796
• XenbaseID: XB-GENE-971799
• Length: 513
• Species: Xenopus tropicalis
• Alignment Length: 513
• Identity: 400/513 - (77%)
• Similarity: 460/513 - (89%)
• Gaps: 4/513 - (0%)

  Fly     1 MSIEIESADVIRLIQQYLKESNLMKTLQTLQEETGVSLNTVDSVDGFVQDISNGHWDTVLKVTQS 65
            |||||||:||||||.|||||::|.:||.||||||.||||||||::.||.||::|||||||:..||
 Frog     1 MSIEIESSDVIRLIMQYLKENSLHRTLATLQEETTVSLNTVDSIESFVADINSGHWDTVLQAIQS 65

  Fly    66 LKLPDKKLLNLYEQIVLELIELRELGAARSLLRQTDPMTMLKQQEPERYIHLENMLQRAYFDPRE 130
            ||||||.|::||||:|||||||||||||||||||||||.||||.:|||||||||:|.|:||||||
 Frog    66 LKLPDKTLIDLYEQVVLELIELRELGAARSLLRQTDPMIMLKQNQPERYIHLENLLARSYFDPRE 130

  Fly   131 AYAEGSSKEKRRTVIAQELSGEVHVVPSSRLLALLGQALKWQQHQGLLPPGTTIDLFRGKAAMKD 195
            ||.:||||||||..|||.|:|||.|||.|||:|||||||||||||||||||..|||||||||:||
 Frog   131 AYPDGSSKEKRRAAIAQALAGEVSVVPPSRLMALLGQALKWQQHQGLLPPGMIIDLFRGKAAVKD 195

  Fly   196 QEEEMYPTQLFRQIKFGQKSHVECAQFSPDGQYLITGSVDGFLEVWNFTTGKVRKDLKYQAQDQF 260
            .|||.:||||.|.||||||||||||:||||||||:|||||||:|||||||||:||||||||||.|
 Frog   196 VEEEKFPTQLSRHIKFGQKSHVECARFSPDGQYLVTGSVDGFIEVWNFTTGKIRKDLKYQAQDNF 260

  Fly   261 MMMEQAVLALNFSRDSEMVASGAQDGQIKVWRIITGQCLRKFEKAHTKGITCLQFSRDNSQVLSA 325
            |||:.|||.:.||||:||:|:|||||:||||:|.:|||||:||:||:||:|||.||:|.||:|||
 Frog   261 MMMDDAVLCMCFSRDTEMLATGAQDGKIKVWKIQSGQCLRRFERAHSKGVTCLSFSKDCSQILSA 325

  Fly   326 SFDYTVRLHGLKSGKMLKEFKGHSSFVNEATFTPDGHSVLSASSDGTVKVWSLKTTECVATYKPL 390
            |||.|:|:|||||||.||||:||||||||||||.|||.::|||||||||:|::|||||..|:|.|
 Frog   326 SFDQTIRVHGLKSGKTLKEFRGHSSFVNEATFTQDGHYIISASSDGTVKIWNMKTTECSNTFKSL 390

  Fly   391 GN----ELAVNTVLILPKNPEHFIVCNRSNTVVIMNMQGQIVRSFSSGKREGGAFISATLSPRGE 451
            |:    ::.||:|::||||||||:|||||||||||||||||||||||||||||.|:..|||||||
 Frog   391 GSTAGTDITVNSVILLPKNPEHFVVCNRSNTVVIMNMQGQIVRSFSSGKREGGDFVCCTLSPRGE 455

  Fly   452 FIYCAGEDQVLYCFSVSSGKLERTLNVHEKDVIGLTHHPHQNLLASYSEDGLLKLWKP 509
            :|||.|||.||||||..:|||||||.||||||||:.|||||||:.:||||||||||||
 Frog   456 WIYCVGEDFVLYCFSTVTGKLERTLTVHEKDVIGIAHHPHQNLIGTYSEDGLLKLWKP 513

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Smu1	NP_650766.1	LisH_TPL	7..36	CDD:375350	21/28 (75%)
		CTLH	40..90	CDD:128914	36/49 (73%)
		WD40	<203..509	CDD:441893	238/309 (77%)
		WD40 repeat	218..256	CDD:293791	33/37 (89%)
		WD40 repeat	267..303	CDD:293791	24/35 (69%)
		WD40 repeat	311..346	CDD:293791	26/34 (76%)
		WD40 repeat	352..432	CDD:293791	60/83 (72%)
		WD40 repeat	440..477	CDD:293791	26/36 (72%)
		WD40 repeat	483..507	CDD:293791	18/23 (78%)
smu1	NP_989188.1	Required for interaction with ik. /evidence=ECO:0000250|UniProtKB:Q2TAY7	1..315		248/313 (79%)
		LisH_TPL	7..36	CDD:375350	21/28 (75%)
		CTLH	40..90	CDD:128914	36/49 (73%)
		WD40	141..513	CDD:441893	287/371 (77%)
		WD40 repeat	219..262	CDD:293791	37/42 (88%)
		WD40 repeat	268..305	CDD:293791	25/36 (69%)
		WD 3. /evidence=ECO:0000255	305..346		30/40 (75%)
		WD40 repeat	310..346	CDD:293791	26/35 (74%)
		WD 4. /evidence=ECO:0000255	347..386		30/38 (79%)
		WD40 repeat	353..393	CDD:293791	28/39 (72%)
		WD 5. /evidence=ECO:0000255	395..436		31/40 (78%)
		WD40 repeat	400..436	CDD:293791	31/35 (89%)
		WD 6. /evidence=ECO:0000255	440..479		28/38 (74%)
		WD40 repeat	444..481	CDD:293791	26/36 (72%)
		WD 7. /evidence=ECO:0000255	482..513		25/30 (83%)
		WD40 repeat	487..511	CDD:293791	18/23 (78%)