Protein Alignment Sgsh and Gns

DIOPT Version :10

• Sequence 1: NP_650760.1
• Gene: Sgsh / 42266
• FlyBaseID: FBgn0038660
• Length: 524
• Species: Drosophila melanogaster
• Sequence 2: NP_083640.1
• Gene: Gns / 75612
• MGIID: 1922862
• Length: 544
• Species: Mus musculus
• Alignment Length: 563
• Identity: 121/563 - (21%)
• Similarity: 215/563 - (38%)
• Gaps: 184/563 - (32%)

  Fly     7 IFTLWLIAGC-----SAGPQNVLLLLADDAGFESGAYLNKFCQTPNLDALAKRGLLFNNAFTSVS 66
            :..|.|:.||     :|...||||||.||...|.|. :....:|..|  :.::|:.|::|:...:
Mouse    20 LLLLPLLGGCLGLVGAARRPNVLLLLTDDQDAELGG-MTPLKKTKAL--IGEKGMTFSSAYVPSA 81

  Fly    67 SCSPSRSQLLTGQAGHSSGMYGLHQGVHN----------FNVLPDTGSLPNLIRDQSG------G 115
            .|.|||:.:|||:..|:      |..|:|          :..:.:..:.|.:::...|      |
Mouse    82 LCCPSRASILTGKYPHN------HHVVNNTLEGNCSSKAWQKIQEPYTFPAILKSVCGYQTFFAG 140

  Fly   116 RIL-------SGIIGKKHVGAANNFRFDFEQTEEQH----SINQIGRNITRMKEYARQFLKQA-- 167
            :.|       :|  |.:|:....::.:..|:..:.:    |||  |:.....:.|:..:|...
Mouse   141 KYLNEYGAPDAG--GLEHIPLGWSYWYALEKNSKYYNYTLSIN--GKARKHGENYSVDYLTDVLA 201

  Fly   168 ---------KDEKKPFFLMVGFHDPHRCGHITPQFGEFCERWGSGEEGMGSIPDWKPIYYDWRNL 223
                     |...:|||:|:....||......||:.:                       .::|:
Mouse   202 NLSLDFLDYKSNSEPFFMMISTPAPHSPWTAAPQYQK-----------------------AFQNV 243

  Fly   224 DVPA------------WL------PDT--------DVVRQELAAQYMTISRLDQGVGLMLKELEA 262
            ..|.            ||      |.|        |..|:    ::.|:..:|..|..::|.|::
Mouse   244 IAPRNKNFNIHGTNKHWLIRQAKTPMTNSSIRFLDDAFRR----RWQTLLSVDDLVEKLVKRLDS 304

  Fly   263 AGVADQTLVIYTSDNGP-----PFPGGRTNLYEHGIRSPLIISSPNKEDRHHEATAAMVSLLDIY 322
            .|..|.|.:.||||||.     ..|..:..|||..|:.||::..|.  .:.::.:..:||.:|:.
Mouse   305 TGELDNTYIFYTSDNGYHTGQFSLPIDKRQLYEFDIKVPLLVRGPG--IKPNQTSKMLVSNIDLG 367

  Fly   323 PSVMDALQIPRPNDTKIVGRSILPVLREEPPIKESDSVFGSHSYHEVTMAYPMRMVRNRRYKLIH 387
            |:::|...... |.|::.|.|:||:|:.:                           ||..::...
Mouse   368 PTILDLAGYDL-NKTQMDGMSLLPILKGD---------------------------RNLTWRSDV 404

  Fly   388 NINYWAD-------------------FP--IDQDFYTSPTFQQILNATLRKQTLPWYRSLLQYYQ 431
            .:.|..:                   ||  :.:|.|.: |:     |.:|..:..|.   |||.:
Mouse   405 LVEYQGEGRNVTDPTCPSLSPGVSQCFPDCVCEDAYNN-TY-----ACVRTLSSLWN---LQYCE 460

  Fly   432 RPEW----ELYDIKTDPLERFNLADK------AKYNGTLKQLR 464
            ..:.    |:|:|..||.:..|:|..      .|.|..|..|:
Mouse   461 FDDQEVFVEVYNITADPDQITNIAKSIDPELLGKMNYRLMMLQ 503

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sgsh	NP_650760.1	SGSH	22..471	CDD:293751	116/543 (21%)
Gns	NP_083640.1	G6S	38..487	CDD:293766	112/527 (21%)