Protein Alignment Sgsh and ARSF

DIOPT Version :9

• Sequence 1: NP_650760.1
• Gene: Sgsh / 42266
• FlyBaseID: FBgn0038660
• Length: 524
• Species: Drosophila melanogaster
• Sequence 2: XP_011543824.1
• Gene: ARSF / 416
• HGNCID: 721
• Length: 607
• Species: Homo sapiens
• Alignment Length: 628
• Identity: 144/628 - (22%)
• Similarity: 217/628 - (34%)
• Gaps: 213/628 - (33%)

  Fly    22 NVLLLLADDAGF-ESGAYLNKFCQTPNLDALAKRGLLFNNAFTSVSSCSPSRSQLLTGQAGHSSG 85
            |::|::.||.|. :.|.|.|...:||::|.||:.|:......::.|.||||||..|||:....||
Human    48 NIVLIMVDDLGIGDLGCYGNDTMRTPHIDRLAREGVRLTQHISAASLCSPSRSAFLTGRYPIRSG 112

  Fly    86 MY--GLHQGVHNFNV---LP-DTGSLPNLIRDQSGGRILSGIIGKKHVGAANNFRFDFEQTEEQH 144
            |.  |..:.:.|..|   || :..:|..|::.|.   ..:|:|||.|.|...:.|.|    :..|
Human   113 MVSSGNRRVIQNLAVPAGLPLNETTLAALLKKQG---YSTGLIGKWHQGLNCDSRSD----QCHH 170

  Fly   145 SINQIGRNITRMKEYARQFLKQAKDEKKPFFLMVG-FHDPHR------------C------GHIT 190
            ..|           |...:.     ...||.|:.. :.||.|            |      ..:|
Human   171 PYN-----------YGFDYY-----YGMPFTLVDSCWPDPSRNTELAFESQLWLCVQLVAIAILT 219

  Fly   191 PQFGEFCERWGSGEEGMGSIPDW----------------------KPIYYD-------------- 219
            ..||:.        .|..|:| |                      .|:|:|
Human   220 LTFGKL--------SGWVSVP-WLLIFSMILFIFLLGYAWFSSHTSPLYWDCLLMRGHEITEQPM 275

  Fly   220 ----------------------------WRNLDVPAWLPDTD----VVRQELAAQYMTISRLDQG 252
                                        :..|.|...||.||    ..:..|...  .:..:|..
Human   276 KAERAGSIMVKEAISFLERHSKETFLLFFSFLHVHTPLPTTDDFTGTSKHGLYGD--NVEEMDSM 338

  Fly   253 VGLMLKELEAAGVADQTLVIYTSDNGPPFP--------GGRTNLY---------EHGIRSPLIIS 300
            ||.:|..::..|:.:.|||.:|||:|....        ||...:|         |.|||.|.|:.
Human   339 VGKILDAIDDFGLRNNTLVYFTSDHGGHLEARRGHAQLGGWNGIYKGGKGMGGWEGGIRVPGIVR 403

  Fly   301 SPNKEDRHH---EATAAMVSLLDIYPSVMDALQIPRPNDTKIVGRSILPVLREEPPIKESDSVFG 362
            .|.|.....   |.|    ||:||.|:|........|.|..|.||.::|:|:            |
Human   404 WPGKVPAGRLIKEPT----SLMDILPTVASVSGGSLPQDRVIDGRDLMPLLQ------------G 452

  Fly   363 S--HSYHEVTMAYPMRMVRNRRYKLIHNINYWADFPIDQD------FYTSPTFQQILNATLRKQT 419
            :  ||.||....|        ....:|.:.:   .|.|..      .|.:|.||...:......:
Human   453 NVRHSEHEFLFHY--------CGSYLHAVRW---IPKDDSGSVWKAHYVTPVFQPPASGGCYVTS 506

  Fly   420 L-PWYRSLLQYYQRPEWELYDIKTDPLERFNLADKA---------KYNGTLKQLREQL--FDWQV 472
            | ..:...:.|:..|  .|:|:..||.|...|....         |....||:.:|.:  ..:|:
Human   507 LCRCFGEQVTYHNPP--LLFDLSRDPSESTPLTPATEPLHDFVIKKVANALKEHQETIVPVTYQL 569

  Fly   473 ATKDPWR-----CAPHAVLQEQGVYKDQPVCLTLGHEALQRPK 510
            :..:..|     |.        ||:   |.||....|.:.:|:
Human   570 SELNQGRTWLKPCC--------GVF---PFCLCDKEEEVSQPR 601

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sgsh	NP_650760.1	AslA	17..476	CDD:225661	135/587 (23%)
		SGSH	22..471	CDD:293751	134/582 (23%)
ARSF	XP_011543824.1	AslA	44..560	CDD:225661	133/574 (23%)
		ALP_like	46..570	CDD:304875	135/584 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3119
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.810