Protein Alignment Sgsh and STS

DIOPT Version :9

• Sequence 1: NP_650760.1
• Gene: Sgsh / 42266
• FlyBaseID: FBgn0038660
• Length: 524
• Species: Drosophila melanogaster
• Sequence 2: NP_001307679.1
• Gene: STS / 412
• HGNCID: 11425
• Length: 590
• Species: Homo sapiens
• Alignment Length: 609
• Identity: 145/609 - (23%)
• Similarity: 225/609 - (36%)
• Gaps: 176/609 - (28%)

  Fly     7 IFTLWLIAGCSAGPQNVLLLLADDAGF-ESGAYLNKFCQTPNLDALAKRGLLFNNAFTSVSSCSP 70
            :|.||.....:|...|::|::|||.|. :.|.|.||..:|||:|.||..|:.......:...|:|
Human    20 LFFLWEAESHAASRPNIILVMADDLGIGDPGCYGNKTIRTPNIDRLASGGVKLTQHLAASPLCTP 84

  Fly    71 SRSQLLTGQAGHSSGMYGLHQ-GVHNFNVLPDTGSLP-------NLIRDQSGGRILSGIIGKKHV 127
            ||:..:||:....|||....: ||..|..  .:|.||       .|::||.   ..:.:|||.|:
Human    85 SRAAFMTGRYPVRSGMASWSRTGVFLFTA--SSGGLPTDEITFAKLLKDQG---YSTALIGKWHL 144

  Fly   128 GAANNFRFDFEQTEEQHSINQI-GRNITRMKE--------YARQFLKQAKDEKKPFFL---MVG- 179
            |.:.:.:.||......|..|.. |.::|.:::        :...|       |:..||   :||
Human   145 GMSCHSKTDFCHHPLHHGFNYFYGISLTNLRDCKPGEGSVFTTGF-------KRLVFLPLQIVGV 202

  Fly   180 -------------FHDP--------HRCGHITPQFGEFCERWGSGEEGMGSIPDWKPI-YYDWRN 222
                         .|.|        .....|...|             :|.:..::|: .:..||
Human   203 TLLTLAALNCLGLLHVPLGVFFSLLFLAALILTLF-------------LGFLHYFRPLNCFMMRN 254

  Fly   223 LDVPAWLPDTDVVRQEL---AAQYM--------------------------------------TI 246
            .::.......|.:.|.|   |||::                                      .:
Human   255 YEIIQQPMSYDNLTQRLTVEAAQFIQRNTETPFLLVLSYLHVHTALFSSKDFAGKSQHGVYGDAV 319

  Fly   247 SRLDQGVGLMLKELEAAGVADQTLVIYTSDNGPP-----------------FPGGRTNLYEHGIR 294
            ..:|..||.:|..|:...:|:.||:.:|||.|..                 :.||:.|.:|.|||
Human   320 EEMDWSVGQILNLLDELRLANDTLIYFTSDQGAHVEEVSSKGEIHGGSNGIYKGGKANNWEGGIR 384

  Fly   295 SPLIISSP------NKEDRHHEATAAMVSLLDIYPSVMDALQIPRPNDTKIVGRSILPVLREEPP 353
            .|.|:..|      .|.|   |.|:.|    ||:|:|......|.|.|..|.||.::|:|  |..
Human   385 VPGILRWPRVIQAGQKID---EPTSNM----DIFPTVAKLAGAPLPEDRIIDGRDLMPLL--EGK 440

  Fly   354 IKESDSVFGSHSYHEVTMAYPMRMVRNRRYKLIHNINYWADFPIDQDFYTSPTFQQI-LNATLRK 417
            .:.||        ||....|....:...|:...::.:.|..|     |:| |.|..: .|.....
Human   441 SQRSD--------HEFLFHYCNAYLNAVRWHPQNSTSIWKAF-----FFT-PNFNPVGSNGCFAT 491

  Fly   418 QTLPWYRSLLQYYQRPEWELYDIKTDPLERFNL--ADKAKYNGTLKQLRE-------------QL 467
            .....:.|.:.::..|  .|:||..||.||..|  |.:.::...||.::|             ..
Human   492 HVCFCFGSYVTHHDPP--LLFDISKDPRERNPLTPASEPRFYEILKVMQEAADRHTQTLPEVPDQ 554

  Fly   468 FDWQVATKDPW--RCAPHAVLQEQ 489
            |.|......||  .|.|...|..|
Human   555 FSWNNFLWKPWLQLCCPSTGLSCQ 578

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sgsh	NP_650760.1	AslA	17..476	CDD:225661	136/582 (23%)
		SGSH	22..471	CDD:293751	134/572 (23%)
STS	NP_001307679.1	AslA	30..555	CDD:225661	134/574 (23%)
		ES	33..557	CDD:293778	134/573 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3119
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810