DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Sgsh and CG7402

DIOPT Version :9

Sequence 1:NP_650760.1 Gene:Sgsh / 42266 FlyBaseID:FBgn0038660 Length:524 Species:Drosophila melanogaster
Sequence 2:NP_649023.1 Gene:CG7402 / 39994 FlyBaseID:FBgn0036768 Length:579 Species:Drosophila melanogaster


Alignment Length:578 Identity:136/578 - (23%)
Similarity:225/578 - (38%) Gaps:161/578 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly     7 IFTLWLIAGCSAGPQNVLLLLADDAGFESGAY--LNKFCQTPNLDALAKRGLLFNNAFTSVSSCS 69
            |.:|...:|.|..| |::::|.||.|....::  .|:.. |||:||||..|:|.|..:.. :.|:
  Fly    15 ILSLAYGSGYSTKP-NIVIILIDDMGMNDVSFHGSNQIL-TPNIDALAYNGILLNKHYVP-NLCT 76

  Fly    70 PSRSQLLTGQAGHSSGMYGLHQGVHNFNVLPD--------TGSLPNLIRDQSGGRILSGIIGKKH 126
            |||:.||||:       |.:|.|:.:|.::.|        ...:|.:.||..   ..:.::||.|
  Fly    77 PSRATLLTGK-------YPIHTGMQHFVIITDEPWGLPQRERLMPEIFRDAG---YSTHLVGKWH 131

  Fly   127 VGAANNFRFDFEQTEE----------------QHSINQIGRNITRMKEYARQ------------- 162
            :|.   :|.|...|..                .|.:..:.||.:...::.|.             
  Fly   132 LGF---WRKDLTPTMRGFDHHFGYYNGYIDYYDHQVRMLDRNYSAGLDFRRDLEPCPEANGTYAT 193

  Fly   163 --FLKQAK------DEKKPFFLMVGFHDPHRCGHITPQFGEFCERWGSGEEGMGSIPDWKPIYYD 219
              |..:||      |:.||.|:::        .|:....|                         
  Fly   194 EAFTSEAKRIIEQHDKSKPLFMVL--------SHLAVHTG------------------------- 225

  Fly   220 WRNLDVPAWLPDTDV-----VRQELAAQYM-TISRLDQGVGLMLKELEAAGVADQTLVIYTSDNG 278
              |.|.|...|:.:|     :|......|. .||.||:.|...:..|:..|:.:.::::..||||
  Fly   226 --NEDSPMQAPEEEVAKFPHIRDPKRRTYAGMISSLDKSVAQTIGALKDNGMLNNSIILLYSDNG 288

  Fly   279 P-------------PFPGGRTNLYEHGIRSPLIISSPNKEDRHHEATAAMVSLLDIYPSVMDALQ 330
            .             |:.|.:.:.:|.||||...:.||..::|.:.:..| :..:|..|::..|..
  Fly   289 APTIGIHSNAGSNYPYRGQKESPWEGGIRSAGALWSPLLKERGYVSNQA-IHAVDWLPTLAGAAG 352

  Fly   331 IPRPNDTKIVGRSILPVL--REEPP----IKESDSVFGSHSYHEVTMAYPMRMVRNRRYKLIHNI 389
            :..|.|..:.|.::.|:|  .|||.    |...|.|||..||...|:.|........||      
  Fly   353 VSLPQDLPLDGINLWPMLSGNEEPKPRTMIHVLDEVFGYSSYMRDTLKYVNGSSFKGRY------ 411

  Fly   390 NYW-------ADFPIDQDF---YTSPTFQQIL-NATLRKQTLPWYRS--------------LLQY 429
            :.|       .|.|:.:.:   ..:...|.:| |..|.|..:...||              |..:
  Fly   412 DQWLGELETNEDDPLGESYEQHVLASDVQSLLGNRGLTKDRIRQMRSEATETCPPIEGQNPLESH 476

  Fly   430 YQRPEWE---LYDIKTDPLERFNLADKAKYNGTLKQLREQLFDWQVATKDPWRCAPHA 484
            ::....:   .:|:..||.||:|||.  .|...|:||.::|...: .|..|....||:
  Fly   477 FKCEPLKAPCFFDLAKDPCERYNLAQ--MYPLQLQQLADELEQIR-KTAIPSARVPHS 531

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
SgshNP_650760.1 AslA 17..476 CDD:225661 130/558 (23%)
SGSH 22..471 CDD:293751 127/548 (23%)
CG7402NP_649023.1 PRK13759 25..459 CDD:237491 114/491 (23%)
4-S 28..436 CDD:293753 107/465 (23%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C45466502
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG3119
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
32.740

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