Protein Alignment Sgsh and GALNS

DIOPT Version :9

• Sequence 1: NP_650760.1
• Gene: Sgsh / 42266
• FlyBaseID: FBgn0038660
• Length: 524
• Species: Drosophila melanogaster
• Sequence 2: XP_011521284.1
• Gene: GALNS / 2588
• HGNCID: 4122
• Length: 581
• Species: Homo sapiens
• Alignment Length: 534
• Identity: 127/534 - (23%)
• Similarity: 195/534 - (36%)
• Gaps: 166/534 - (31%)

  Fly     9 TLWLIAGCSAGPQNVLLLLADDAGF---ESGAYLNKFCQTPNLDALAKRGLLFNNAFTSVSSCSP 70
            |.|...|.:....:     |.||..   :.|.|.....:|||||.:|..||||.|.:::...|||
Human    28 TAWADRGAAPSCTH-----AGDAEMGWGDLGVYGEPSRETPNLDRMAAEGLLFPNFYSANPLCSP 87

  Fly    71 SRSQLLTGQAGHSSGMYGLHQGVHN-------FNVLPDTGS-LPNLIRDQSGGRILSGIIGKKHV 127
            ||:.||||:....:|.|..:....|       ...:||:.. ||.|:: ::|  .:|.|:||.|:
Human    88 SRAALLTGRLPIRNGFYTTNAHARNAYTPQEIVGGIPDSEQLLPELLK-KAG--YVSKIVGKWHL 149

  Fly   128 GAANNFR-----FD---------FEQTEEQHSIN--------QIGR--------------NITRM 156
            |....|.     ||         |...:.:...|        .:||              |:|::
Human   150 GHRPQFHPLKHGFDEWFGSPNCHFGPYDNKARPNIPVYRDWEMVGRYYEEFPINLKTGEANLTQI 214

  Fly   157 -KEYARQFLK-QAKDEKKPFFLMVGFHDPHRCGHITPQFGEFCERWGSGEEGMGSIPDWKPIYYD 219
             .:.|..|:| ||:..  ||||.......|...:.:..|      .|:.:.|...
Human   215 YLQEALDFIKRQARHH--PFFLYWAVDATHAPVYASKPF------LGTSQRGRYG---------- 261

  Fly   220 WRNLDVPAWLPDTDVVRQELAAQYMTISRLDQGVGLMLKELEAAGVADQTLVIYTSDNGP----- 279
                         |.||:           :|..:|.:|:.|:...|||.|.|.:|||||.
Human   262 -------------DAVRE-----------IDDSIGKILELLQDLHVADNTFVFFTSDNGAALISA 302

  Fly   280 --------PFPGGRTNLYEHGIRSPLIISSPNKEDRHHEATAAMV-----SLLDIYPSVMDALQI 331
                    ||..|:...:|.|:|.|.:...|.      ..||..|     |::|::.:.:....:
Human   303 PEQGGSNGPFLCGKQTTFEGGMREPALAWWPG------HVTAGQVSHQLGSIMDLFTTSLALAGL 361

  Fly   332 PRPNDTKIVGRSILPVLRE----EPPI--KESDSV----FGSHSYHEVTMAYPMRMVRNRRYKLI 386
            ..|:|..|.|.::||.|.:    :.||  ...|::    .|.|..|..|..
Human   362 TPPSDRAIDGLNLLPTLLQGRLMDRPIFYYRGDTLMAATLGQHKAHFWTWT-------------- 412

  Fly   387 HNINYWADFPIDQDFYTSPTFQQILNATLRKQT-LPWYRSLLQYYQRPEWELYDIKTDPLERFNL 450
               |.|.:|....||........:....|...| ||.              ::.:..||.|||.|
Human   413 ---NSWENFRQGIDFCPGQNVSGVTTHNLEDHTKLPL--------------IFHLGRDPGERFPL 460

  Fly   451 A-DKAKYNGTLKQL 463
            : ..|:|...|.::
Human   461 SFASAEYQEALSRI 474

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sgsh	NP_650760.1	AslA	17..476	CDD:225661	124/526 (24%)
		SGSH	22..471	CDD:293751	124/521 (24%)
GALNS	XP_011521284.1	GALNS	46..500	CDD:293776	121/511 (24%)
		AslA	46..489	CDD:225661	121/511 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3119
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810