DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sgsh and CG30059

DIOPT Version :9

Sequence 1:	NP_650760.1	Gene:	Sgsh / 42266	FlyBaseID:	FBgn0038660	Length:	524	Species:	Drosophila melanogaster
Sequence 2:	NP_610872.1	Gene:	CG30059 / 246425	FlyBaseID:	FBgn0260475	Length:	492	Species:	Drosophila melanogaster

Alignment Length:	549	Identity:	123/549 - (22%)
Similarity:	193/549 - (35%)	Gaps:	170/549 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 NVLLLLADDAGFESGAYLNKFCQTPNLDALAKRGLLFNNAFTSVSSCSPSRSQLLTGQAGH---- 82
            |:||:|:||...|   ....|.....::.|...|.||:||:|....|.|:|:.||||...|
  Fly    25 NILLILSDDQDVE---LRGMFPMEHTIEMLGFGGALFHNAYTPSPICCPARTSLLTGMYAHNHGT 86

  Fly    83 -----SSGMYGLHQGVHNFNVLPDTGSLPNLIRDQS-----GGRILSGIIGKKHVGAA-NNF--- 133
                 |.|.||.|     :....:..:||.:::...     ||:.|:...|...|... |||
  Fly    87 RNNSVSGGCYGPH-----WRRALEPRALPYILQQHGYNTFFGGKYLNQYWGAGDVPKGWNNFYGL 146

  Fly   134 -----RFDFEQTEEQHSINQIGRNIT-RMKEYARQFLKQAKDEKKPFFLMV---GFHDPHRCGHI 189
                 .:::...|...:::.....:: .:::.|..||:.|....:|||.||   ..|:|     .
  Fly   147 HGNSRYYNYTLRENTGNVHYESTYLSDLLRDRAADFLRNATQSSEPFFAMVAPPAAHEP-----F 206

  Fly   190 TPQFGEFCERWGSGEEGMGS------IPDWKPIYYD--WRNLDVPAWLPDTDV--VRQELAAQYM 244
            ||         ....||:.|      .|.:..:..|  |. :.....||:..:  :......::.
  Fly   207 TP---------APRHEGVFSHIEALRTPSFNQVKQDKHWL-VRAARRLPNETINTIDTYFQKRWE 261

  Fly   245 TISRLDQGVGLMLKELEAAGVADQTLVIYTSDNG-------PPFPGGRTNLYEHGIRSPLIISSP 302
            |:..:|:.|..::..|......:.|.:|||||||       .||  .:...||..|..||:|..|
  Fly   262 TLLAVDELVVTLMGVLNDTQSLENTYIIYTSDNGYHVGQFAQPF--DKRQPYETDINVPLLIRGP 324

  Fly   303 NKEDRHHEATAAMVSLLDIYPSVMDALQIPRPNDTKIVGRSILPVLREEPPIKESDSVFGSHSYH 367
            ......|..||  |||:|:.|:::....|..|                        |.....|:|
  Fly   325 GIAPESHIDTA--VSLVDLAPTILAWADIDTP------------------------SYMDGQSFH 363

  Fly   368 EVTMAYPMRMVRNRRYKLIHNINYWADFPIDQDFYTSPTFQQILNATLRKQTLPW---------- 422
            |:.:....|:....|..|   |.||.:       .|..||         ....||
  Fly   364 ELLLNKRRRVPFFERSLL---IEYWGE-------GTLATF---------NPECPWPEKDRLAQCT 409

  Fly   423 --------------YRSLLQYYQRPE------------WELYDIKTDPLERFNLA------DKAK 455
                          |..|.....|.:            .|.||::.||.:..|:|      ::|.
  Fly   410 PAADCHCQDAWNNTYACLRNIRHREDRIYCEFRDNENFLEAYDLQLDPFQMTNIAYDLLPIERAL 474

  Fly   456 YNGTLKQLREQLFDWQVATKDPWRCAPHA 484
            |:..||.|.:              |:.|:
  Fly   475 YSLRLKNLTQ--------------CSGHS 489

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sgsh	NP_650760.1	AslA	17..476	CDD:225661	121/539 (22%)
Sgsh	NP_650760.1	SGSH	22..471	CDD:293751	121/534 (23%)
CG30059	NP_610872.1	G6S	24..467	CDD:293766	116/511 (23%)
CG30059	NP_610872.1	AslA	24..464	CDD:225661	115/508 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45466497
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3119
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.830