Protein Alignment Sgsh and ARSG

DIOPT Version :9

• Sequence 1: NP_650760.1
• Gene: Sgsh / 42266
• FlyBaseID: FBgn0038660
• Length: 524
• Species: Drosophila melanogaster
• Sequence 2: XP_011522838.1
• Gene: ARSG / 22901
• HGNCID: 24102
• Length: 552
• Species: Homo sapiens
• Alignment Length: 644
• Identity: 139/644 - (21%)
• Similarity: 217/644 - (33%)
• Gaps: 265/644 - (41%)

  Fly     6 WIFTLWLIAG-------------CSAG-----PQNVLLLLADDAGF-ESGAYLNKFCQTPNLDAL 51
            |:|...|:||             |.:|     ..|.:::||||.|: :.||...:...|.|||.:
Human     3 WLFLKVLLAGVSFSGFLYPLVDFCISGKTRGQKPNFVIILADDMGWGDLGANWAETKDTANLDKM 67

  Fly    52 AKRGLLFNNAFTSVSSCSPSRSQLLTGQAGHSSGMYGLHQGVHNFNVLPDTGSLP------NLIR 110
            |..|:.|.:...:.|:|||||:.||||:.|..:|:      ..||.| ...|.||      ..:.
Human    68 ASEGMRFVDFHAAASTCSPSRASLLTGRLGLRNGV------TRNFAV-TSVGGLPLNETTLAEVL 125

  Fly   111 DQSGGRILSGIIGKKHVGAAN----NFR-FDF--------------------------------- 137
            .|:|  .::|||||.|:|...    ||| ||:
Human   126 QQAG--YVTGIIGKWHLGHHGSYHPNFRGFDYYFGIPYSHDMGCTDTPGYNHPPCPACPQGDGPS 188

  Fly   138 ----------------------EQTEEQHSINQIGRNITRMKEYARQFLKQAKDEKKPFFLMVGF 180
                                  ||.....|:.|      :..|.|.||:::|....:||.|.|..
Human   189 RNLQRDCYTDVALPLYENLNIVEQPVNLSSLAQ------KYAEKATQFIQRASTSGRPFLLYVAL 247

  Fly   181 HDPHRCGHITPQFGEFCERWGSGEEGMGSIPDWKPIYYDWRNLDVPAWLPDTDVVRQELAAQYMT 245
            ...|....:|.               :.:.|..:.:|      ....|
Human   248 AHMHVPLPVTQ---------------LPAAPRGRSLY------GAGLW----------------- 274

  Fly   246 ISRLDQGVGLMLKELEAAGVADQTLVIYTSDNGP------------PFPG----------GRTNL 288
              .:|..|| .:|:.....|.:.|.:.:|.||||            ||.|          .:...
Human   275 --EMDSLVG-QIKDKVDHTVKENTFLWFTGDNGPWAQKCELAGSVGPFTGFWQTRQGGSPAKQTT 336

  Fly   289 YEHGIRSPLIISSPNKEDRHHEATAAMVSLLDIYPSVMDALQIPRPNDTKIVGRSILPVL--REE 351
            :|.|.|.|.:...|.:...:..:| |::|:|||:|:|:...|...|...:..|..:..||  |.:
Human   337 WEGGHRVPALAYWPGRVPVNVTST-ALLSVLDIFPTVVALAQASLPQGRRFDGVDVSEVLFGRSQ 400

  Fly   352 PPIKESDSVFGS---------------HSYHEVTMAYP----------MRMVRNRRYKLIHNINY 391
            |..:|.::..|.               |.:  :.:.:|          ::.||..|||.
Human   401 PGHREEEAGGGKEAEGAQSPLCNALQMHGF--LVLFHPNSGAAGEFGALQTVRLERYKA------ 457

  Fly   392 WADFPIDQDFY-----------TSPTFQQILNATLRKQTLPWYRSLLQYYQRPEWELYDIKTD-- 443
                     ||           |.|..|       .|..|                :::::.|
Human   458 ---------FYITGGARACDGSTGPELQ-------HKFPL----------------IFNLEDDTA 490

  Fly   444 ---PLERFNLADKAKYNGTLKQLREQLFD--WQVA---------TKDPW---RCAPHAV 485
               ||||    ..|:|...|.::|:.|.|  ..:|         |:||.   .|.|:.:
Human   491 EAVPLER----GGAEYQAVLPEVRKVLADVLQDIANDNISSADYTQDPSVTPCCNPYQI 545

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sgsh	NP_650760.1	AslA	17..476	CDD:225661	129/606 (21%)
		SGSH	22..471	CDD:293751	126/582 (22%)
ARSG	XP_011522838.1	ARSG	35..496	CDD:293780	117/557 (21%)
		AslA	35..457	CDD:225661	107/480 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3119
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.810