DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Sgsh and sul-1

DIOPT Version :9

Sequence 1:	NP_650760.1	Gene:	Sgsh / 42266	FlyBaseID:	FBgn0038660	Length:	524	Species:	Drosophila melanogaster
Sequence 2:	NP_508560.1	Gene:	sul-1 / 180619	WormBaseID:	WBGene00006308	Length:	709	Species:	Caenorhabditis elegans

Alignment Length:	559	Identity:	104/559 - (18%)
Similarity:	190/559 - (33%)	Gaps:	169/559 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 NVLLLLADDAGFESGA--YLNKFCQTPNLDALAKRGLLFNNAFTSVSSCSPSRSQLLTGQAGHSS 84
            ||:|:|.||...|.|:  ::.|..|     .:.:||..|.:.:.:...|.||||.:|||...|:.
Worm    36 NVILILTDDQDIELGSMDFMPKTSQ-----IMKERGTEFTSGYVTTPICCPSRSTILTGLYVHNH 95

  Fly    85 GMYGLHQ----------------GVHNFNVLPDTGSLPNLIRDQSGGRILSGIIGKKHVGAANNF 133
            .::..:|                ||:.......|..|...:.:..|..|..| ..:.|....|:.
Worm    96 HVHTNNQNCTGVEWRKVHEKKSIGVYLQEAGYRTAYLGKYLNEYDGSYIPPG-WDEWHAIVKNSK 159

  Fly   134 RFDFEQTEEQHSINQIGRNITRMKEYARQFLKQAKDEK--------------KPFFLMVGFHDPH 184
            .:::       ::|..|.......||.:.:.......:              :||.|::.:..||
Worm   160 FYNY-------TMNSNGEREKFGSEYEKDYFTDLVTNRSLKFIDKHIKIRAWQPFALIISYPAPH 217

  Fly   185 RCGHITPQFGEFCERWGSGEEGMGSIPDWKPIYYDWRNLDVP--AWLPD------------TDVV 235
            ......|||....|...|...|            .|.....|  .||..            ||::
Worm   218 GPEDPAPQFAHMFENEISHRTG------------SWNFAPNPDKQWLLQRTGKMNDVHISFTDLL 270

  Fly   236 RQELAAQYMTISRLDQGVGLMLKELEAAGVADQTLVIYTSDNGPPFPGGRTNL-------YEHGI 293
            .:.   :..|:..:|:|:..:...|........|..|||||:|  :..|:..|       ||..|
Worm   271 HRR---RLQTLQSVDEGIERLFNLLRELNQLWNTYAIYTSDHG--YHLGQFGLLKGKNMPYEFDI 330

  Fly   294 RSPLIISSPN--KEDRHHEATAAMVSLLDIYPSVMDALQIPRPNDTKIVGRSILPVLREEPPIKE 356
            |.|..:..|.  :....:|    :|:.:||.|:::....:|:|  .::.|||:|.::
Worm   331 RVPFFMRGPGIPRNVTFNE----IVTNVDIAPTMLHIAGVPKP--ARMNGRSLLELV-------- 381

  Fly   357 SDSVFGSHSYHEVTMAYPMRMVRNRRYKLIHNINYWADFPIDQDFYTSPTFQQILNATLRKQTLP 421
                                .::.::.|.:..:..|.|                 ...:.:..:|
Worm   382 --------------------ALKKKKKKHMTALKPWRD-----------------TILIERGKMP 409

  Fly   422 WYRSLLQYYQRPEWELYDIKTDPLERFNLADKAKYNGTLKQLREQLFDWQVATKDPWRCAPHAVL 486
            ..:.:...|.:.:           ::||     |.|...|:.:.:.:.........|:|. :.|.
Worm   410 KLKKIRDRYIKQK-----------KKFN-----KENRLSKECKRRKWQRDCVHGQLWKCY-YTVE 457

  Fly   487 QEQGVYK------DQPVCLTLGHEALQRPKRRILGQYEE 519
            ....:||      ||..|          .|:|.:..|::
Worm   458 DRWRIYKCRDNWSDQCSC----------RKKREISNYDD 486

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sgsh	NP_650760.1	AslA	17..476	CDD:225661	93/508 (18%)
Sgsh	NP_650760.1	SGSH	22..471	CDD:293751	93/503 (18%)
sul-1	NP_508560.1	G6S	34..376	CDD:293766	80/375 (21%)
		AslA	36..>381	CDD:225661	83/380 (22%)
		ALP_like	<605..654	CDD:304875
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3119
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810