Protein Alignment EndoA and Sh3gl1

DIOPT Version :9

• Sequence 1: NP_001262717.1
• Gene: EndoA / 42265
• FlyBaseID: FBgn0038659
• Length: 369
• Species: Drosophila melanogaster
• Sequence 2: XP_038940178.1
• Gene: Sh3gl1 / 81922
• RGDID: 708456
• Length: 435
• Species: Rattus norvegicus
• Alignment Length: 347
• Identity: 173/347 - (49%)
• Similarity: 236/347 - (68%)
• Gaps: 11/347 - (3%)

  Fly     1 MAFAGLKKQINKANQYMTEKMGGAEGTKLDMDFMEMERKTDVTVELVEELQLKTKEFLQPNPTAR 65
            |:.||||||..||:|.::||:|||||||||.||.|||:|.|:|.:.|.|:.::|.|:|||||.:|
  Rat     1 MSVAGLKKQFYKASQLVSEKVGGAEGTKLDDDFREMEKKVDITSKAVAEVLVRTIEYLQPNPASR 65

  Fly    66 AKMAAVKGISKLSGQAKSNTYPQPEGLLAECMLTYGKKLGEDNSVFAQALVEFGEALKQMADVKY 130
            ||:..:..:||:.||.|:..|||.||||.|||:.:||:||.::: |..||::.||::|::|:||.
  Rat    66 AKLTMLNTVSKIRGQVKNPGYPQSEGLLGECMVRHGKELGGESN-FGDALLDAGESMKRLAEVKD 129

  Fly   131 SLDDNIKQNFLEPLHHMQTKDLKEVMHHRKKLQGRRLDFDCKRRRQAK--DDEIRGAEDKFGESL 193
            |||..:||||::||.::..|||||:.||.|||:|||||||.|::||.|  |:|:|.|.:||.||.
  Rat   130 SLDIEVKQNFIDPLQNLCDKDLKEIQHHLKKLEGRRLDFDYKKKRQGKIPDEELRQALEKFEESK 194

  Fly   194 QLAQVGMFNLLENDTEHVSQLVTFAEALYDFHSQCADVLRGLQETLQEKRSEAESRPRNEFVPKT 258
            ::|:..|.||||.|.|.||||....:|..|:|.|...:|..|.:.|:.:..||.||||.||.|:.
  Rat   195 EVAETSMHNLLETDIEQVSQLSALVDAQLDYHRQAVQILEELADKLKRRVREASSRPRREFKPRP 259

  Fly   259 L--LDL-NLDGGGGGLNEDGTPS-HISSSASPLPSPMRSPAKSMAVTPQRQQQPCCQALYDFEPE 319
            .  .:| .|:...||......|. ..|||......|.|:|:|||...    .||.|:||||||||
  Rat   260 QEPFELGELEQPNGGFPCASAPKITASSSFRSGDKPTRTPSKSMPPL----DQPSCKALYDFEPE 320

  Fly   320 NPGELAFKENDIITLLNRVDDN 341
            |.|||.|:|.|:|||.|::|:|
  Rat   321 NDGELGFREGDLITLTNQIDEN 342

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
EndoA	NP_001262717.1	BAR_Endophilin_A	25..246	CDD:153276	111/222 (50%)
		SH3_Endophilin_A	312..361	CDD:212737	21/30 (70%)
Sh3gl1	XP_038940178.1	BAR_Endophilin_A2	25..247	CDD:153298	111/222 (50%)
		SH3	309..>342	CDD:418401	22/32 (69%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	258	1.000	Domainoid score	I1931
eggNOG	1	0.900	-	-		E1_KOG1118
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	361	1.000	Inparanoid score	I2126
OMA	1	1.010	-	-		QHG52174
OrthoDB	1	1.010	-	-		D474758at33208
OrthoFinder	1	1.000	-	-		FOG0000985
OrthoInspector	1	1.000	-	-		otm46336
orthoMCL	1	0.900	-	-		OOG6_102270
Panther	1	1.100	-	-	O	PTHR14167
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X800
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	13	12.880