Protein Alignment EndoA and sh3gl2b

DIOPT Version :9

• Sequence 1: NP_001262717.1
• Gene: EndoA / 42265
• FlyBaseID: FBgn0038659
• Length: 369
• Species: Drosophila melanogaster
• Sequence 2: NP_001340906.1
• Gene: sh3gl2b / 794400
• ZFINID: ZDB-GENE-170303-2
• Length: 349
• Species: Danio rerio
• Alignment Length: 371
• Identity: 182/371 - (49%)
• Similarity: 257/371 - (69%)
• Gaps: 26/371 - (7%)

  Fly     1 MAFAGLKKQINKANQYMTEKMGGAEGTKLDMDFMEMERKTDVTVELVEELQLKTKEFLQPNPTAR 65
            |:.||||||.:||.|.::||:|||||||||.||.|||:|.|.|...|.::..||.|:|||||.:|
Zfish     1 MSVAGLKKQFHKATQKVSEKVGGAEGTKLDDDFKEMEKKVDTTSRAVLDIMTKTTEYLQPNPASR 65

  Fly    66 AKMAAVKGISKLSGQAKSNTYPQPEGLLAECMLTYGKKLGEDNSVFAQALVEFGEALKQMADVKY 130
            |:::.:..:||:.||.|...|||.|.:|.:.||.:|::|||::| |..||::.||:::::.:||.
Zfish    66 ARLSMINTMSKIRGQDKGPGYPQAETVLGDAMLKFGRELGEESS-FGLALLDAGESMRELGEVKD 129

  Fly   131 SLDDNIKQNFLEPLHHMQTKDLKEVMHHRKKLQGRRLDFDCKRRRQAK--DDEIRGAEDKFGESL 193
            :||..:||||::||.::..|||||:.||.||::|||||||.|::||.|  ||||:.|.:||.||.
Zfish   130 ALDITVKQNFIDPLQNLHDKDLKEIQHHLKKMEGRRLDFDYKKKRQGKVTDDEIKQALEKFDESK 194

  Fly   194 QLAQVGMFNLLENDTEHVSQLVTFAEALYDFHSQCADVLRGLQETLQEKRSEAESRPRNEFVPKT 258
            ::|:..||||||||.|.||||....:|..::|.|.|::|:.|...::::..|...:||.||:||.
Zfish   195 EIAEQSMFNLLENDIEQVSQLAALVQAQVEYHQQAAEILQQLSSKIEDRVKEMSDKPRKEFIPKP 259

  Fly   259 LLDLNL--DGGGGGLNEDGTPSHISSSASPLPSPMRSPAKSMAVTPQRQQQPCCQALYDFEPENP 321
            .::|.|  :...||:|          ||.   ||.||||.        ..||||:|||||||||.
Zfish   260 RMELQLPIETLNGGIN----------SAK---SPARSPAP--------LDQPCCRALYDFEPENE 303

  Fly   322 GELAFKENDIITLLNRVDDNWFEGAVNGRTGYFPQSYVQVQVPLPN 367
            |||.|||.|||||.|::||||:||.::|::|:||.:||.:.||||:
Zfish   304 GELGFKEGDIITLTNQIDDNWYEGMIHGQSGFFPINYVDILVPLPH 349

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
EndoA	NP_001262717.1	BAR_Endophilin_A	25..246	CDD:153276	106/222 (48%)
		SH3_Endophilin_A	312..361	CDD:212737	33/48 (69%)
sh3gl2b	NP_001340906.1	BAR_Endophilin_A1	25..246	CDD:153297	106/221 (48%)
		SH3_Endophilin_A	290..344	CDD:212737	36/53 (68%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	77	1.000	Domainoid score	I8751
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG52174
OrthoDB	1	1.010	-	-		D474758at33208
OrthoFinder	1	1.000	-	-		FOG0000985
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR14167
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X800
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	8	8.030