Protein Alignment EndoA and sh3gl1

DIOPT Version :10

• Sequence 1: NP_620122.2
• Gene: EndoA / 42265
• FlyBaseID: FBgn0038659
• Length: 369
• Species: Drosophila melanogaster
• Sequence 2: NP_989126.1
• Gene: sh3gl1 / 619364
• XenbaseID: XB-GENE-951561
• Length: 366
• Species: Xenopus tropicalis
• Alignment Length: 373
• Identity: 184/373 - (49%)
• Similarity: 256/373 - (68%)
• Gaps: 15/373 - (4%)

  Fly     1 MAFAGLKKQINKANQYMTEKMGGAEGTKLDMDFMEMERKTDVTVELVEELQLKTKEFLQPNPTAR 65
            |:.||||||..||:|.::||:|||||||||.:|.|||:|.|||.:.|.::..||.|:|||||.:|
 Frog     1 MSVAGLKKQFYKASQLVSEKVGGAEGTKLDDEFKEMEKKVDVTTKAVTDVLAKTIEYLQPNPASR 65

  Fly    66 AKMAAVKGISKLSGQAKSNTYPQPEGLLAECMLTYGKKLGEDNSVFAQALVEFGEALKQMADVKY 130
            ||::.:..:||:.||.|:..||||||:|.|.|:.:||.|| |.|.|..||::.||::|::|:||.
 Frog    66 AKLSMLNTMSKIRGQVKNPGYPQPEGVLGETMIKFGKDLG-DESNFGDALLDAGESMKRLAEVKD 129

  Fly   131 SLDDNIKQNFLEPLHHMQTKDLKEVMHHRKKLQGRRLDFDCKRRRQAK--DDEIRGAEDKFGESL 193
            |||..:|||||:||.::..|||||:.||.|||:|||||:|.|::||.|  |:|:|.|.:||.||.
 Frog   130 SLDIEVKQNFLDPLQNLCDKDLKEIQHHLKKLEGRRLDYDYKKKRQGKIPDEELRQAMEKFIESK 194

  Fly   194 QLAQVGMFNLLENDTEHVSQLVTFAEALYDFHSQCADVLRGLQETLQEKRSEAESRPRNEFVPKT 258
            ::|:..|.|||:.|.|.||||....||..|:|.|...:|..|.|.|:::..|:.||.:.||.||.
 Frog   195 EVAETSMINLLDTDVEQVSQLTALVEAQLDYHRQAVQILDELSEKLKDRVRESSSRTKREFKPKP 259

  Fly   259 LLDLNL---DGGGGGLNEDGTPSHISSSASPLPSPMRS--PAKSMAVTPQRQQQPCCQALYDFEP 318
            ......   :...||.:.       .||.:|..|..||  ||::...:.....||||:|||||:|
 Frog   260 RESYEYAESEQSNGGFSN-------PSSKAPASSSFRSEKPARTNNRSSAPLDQPCCKALYDFDP 317

  Fly   319 ENPGELAFKENDIITLLNRVDDNWFEGAVNGRTGYFPQSYVQVQVPLP 366
            ||.|||.|:|:|||||.|::|:||:||.:||::|:||.:||::.||||
 Frog   318 ENDGELGFRESDIITLTNQIDENWYEGMINGQSGFFPVNYVEILVPLP 365

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
EndoA	NP_620122.2	BAR_Endophilin_A	25..246	CDD:153276	113/222 (51%)
		SH3_Endophilin_A	312..361	CDD:212737	31/48 (65%)
sh3gl1	NP_989126.1	BAR_Endophilin_A	25..246	CDD:153276	113/221 (51%)
		SH3_Endophilin_A	307..361	CDD:212737	34/53 (64%)