Protein Alignment EndoA and grb2a

DIOPT Version :9

• Sequence 1: NP_001262717.1
• Gene: EndoA / 42265
• FlyBaseID: FBgn0038659
• Length: 369
• Species: Drosophila melanogaster
• Sequence 2: NP_001007770.1
• Gene: grb2a / 493609
• ZFINID: ZDB-GENE-041121-1
• Length: 217
• Species: Danio rerio
• Alignment Length: 210
• Identity: 50/210 - (23%)
• Similarity: 77/210 - (36%)
• Gaps: 70/210 - (33%)

  Fly   218 AEALYDFHSQCAD--------VLRGLQETLQEKRSEAESRPRNEFVPKTLLD------------- 261
            |.|.|||.:...|        :|:.|.|...:...:||...:..|:||..::
Zfish     3 AIAKYDFKATADDELSFKRGEILKVLNEECDQNWYKAELNGKEGFIPKNYIEMKPHPWFYGKIPR 67

  Fly   262 ------LNLDGGGGGL---NEDGTPSHIS-----------------------------SSASPLP 288
                  ||.....|..   ..:..|...|                             :|.:.|.
Zfish    68 AKAEEMLNKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNSLV 132

  Fly   289 SPMRSPA---------KSMAVTPQRQQQPCCQALYDFEPENPGELAFKENDIITLLNRVDDNWFE 344
            ...||.:         :.:...||....  .|||:||:|:..|||.|:..|.|.:|:..|.||::
Zfish   133 DYHRSTSVSRNQPIFLRDIEQVPQNSTY--VQALFDFDPQEDGELGFRRGDFIQVLDNSDPNWWK 195

  Fly   345 GAVNGRTGYFPQSYV 359
            ||.:|:||.||::||
Zfish   196 GACHGQTGMFPRNYV 210

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
EndoA	NP_001262717.1	BAR_Endophilin_A	25..246	CDD:153276	9/35 (26%)
		SH3_Endophilin_A	312..361	CDD:212737	24/48 (50%)
grb2a	NP_001007770.1	SH3_GRB2_N	1..56	CDD:212879	14/52 (27%)
		SH2_Grb2_like	56..150	CDD:199828	9/93 (10%)
		SH3_GRB2_C	160..212	CDD:212882	25/53 (47%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R571
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.030