Protein Alignment EndoA and Sh3yl1

DIOPT Version :10

• Sequence 1: NP_620122.2
• Gene: EndoA / 42265
• FlyBaseID: FBgn0038659
• Length: 369
• Species: Drosophila melanogaster
• Sequence 2: XP_006240032.1
• Gene: Sh3yl1 / 362724
• RGDID: 1306440
• Length: 350
• Species: Rattus norvegicus
• Alignment Length: 219
• Identity: 56/219 - (25%)
• Similarity: 89/219 - (40%)
• Gaps: 55/219 - (25%)

  Fly   164 GRRLDFDCKRRRQAKD-----DEIRGAEDKFGESLQLAQV-GMFNLLENDTEHVSQLVTFAEALY 222
            |..|:..|...|:..:     .:||..:..||:..|.||. .::.:|.:.||.           |
  Rat   161 GISLEGSCLIERKETNRKFYCQDIRAYDILFGDVPQPAQAEDLYEILNSFTEK-----------Y 214

  Fly   223 DFHSQCADVLRGLQE------------TLQEKRSEAESRPRNEFVPKTLLDLNLDGGGGGLNEDG 275
            :...|..::.:..:|            :.:|...:..|||:....|   :.||. |.....||..
  Rat   215 ETEGQRINLKKVAREQRKVLRLGSLLLSAKELPPKPSSRPQPSRPP---VQLNA-GSQSNRNEYK 275

  Fly   276 TPSHISS---SASPLPSPMRSPAKSMAVTPQRQQQPCCQALYDFEPENPGELAFKENDIITLLNR 337
            ....:||   ....|..|:.       ||          |||.||.:.||:|.|:..|.|.::::
  Rat   276 LYPELSSYHEKTGSLSQPIE-------VT----------ALYSFEGQQPGDLNFQAGDRIIVISK 323

  Fly   338 VDDN--WFEGAVNGRTGYFPQSYV 359
            .|.|  |:||.:.|:||.||.:||
  Rat   324 TDSNFDWWEGKLRGQTGIFPANYV 347

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
EndoA	NP_620122.2	BAR_Endophilin_A	25..246	CDD:153276	18/99 (18%)
		SH3_Endophilin_A	312..361	CDD:212737	23/50 (46%)
Sh3yl1	XP_006240032.1	SYLF_SH3YL1_like	11..209	CDD:211401	12/47 (26%)
		SH3_SH3YL1_like	295..348	CDD:212775	25/70 (36%)