Protein Alignment EndoA and SPOM_SPBC19C2.10

DIOPT Version :10

• Sequence 1: NP_620122.2
• Gene: EndoA / 42265
• FlyBaseID: FBgn0038659
• Length: 369
• Species: Drosophila melanogaster
• Sequence 2: NP_595695.1
• Gene: SPOM_SPBC19C2.10 / 2540758
• PomBaseID: SPBC19C2.10
• Length: 501
• Species: Schizosaccharomyces pombe
• Alignment Length: 502
• Identity: 96/502 - (19%)
• Similarity: 165/502 - (32%)
• Gaps: 170/502 - (33%)

  Fly     6 LKKQINKANQYMTEKMG-GAEGTKLDMDFMEMERKTDVTVELVEELQLKTKEFLQPNPTARAKMA 69
            :.|...|.:|:..||.| ..:.|.|..||..::.:||..:..::::.             |:...
pombe     1 MNKHFAKLSQWTGEKFGFDRQKTTLSDDFCSLKGETDAWLVGMDKIH-------------RSCTR 52

  Fly    70 AVKGISKLSGQAKSNTYPQPEGLLAECMLTYGKKLGEDNS------VFAQALVEFGEALKQMADV 128
            .|:.:.|..|.........|...:....:..|:.|...:|      ::.:::||.|...::..|.
pombe    53 WVRNMDKRKGLLDEKDKQLPVTHVGSSFVELGQALSHSSSNSHTYIMYGKSMVEIGHLQEEFMDY 117

  Fly   129 KYSLDDNIKQNFLEPLHHMQTKDLKEVMHHRKKLQGRRLDFD--------CKRRRQAKDDEIRGA 185
               |:::...|....|...:..|:||     ||::.|||.||        .|:.....::::|.|
pombe   118 ---LNNSFLANLENSLAEFKALDVKE-----KKMENRRLVFDALSTKIQKAKKEESKLEEDLRNA 174

  Fly   186 EDKFGESLQLAQVGMFNLLENDTEHVSQLVTFAEALYDFHSQCADVLRGLQ-------------- 236
            ..|:.|||:..:..|..|.|.:.:.|..:|...:....||.:..|:|:||:
pombe   175 RAKYEESLEEFEDRMVQLKELEPDRVENVVRLLQMQIRFHQKSLDLLKGLEMNGFSKKRDNVNIP 239

  Fly   237 ------------------------------ETLQEKRSEAESRPRNEFVPKTLLDLNLDGGG--- 268
                                          :||:...|..|.......:|....:.:||...
pombe   240 KRTYSARSIPSNISSTNVATTPSNTIFEMDDTLKADSSSNEYHSPTNTLPSYHTEADLDNSSIAS 304

  Fly   269 --------GGLNEDGTPSHIS----------SSASPLP---SPMRSPAKSMAVTPQRQQ------ 306
                    ...|:|.:.:..|          .|:.|:|   .|..|..:|..|.|...|
pombe   305 SNRTQHTEDNYNKDVSDAQNSLGQSAVDLTTPSSPPIPRHTKPKLSTTQSTPVKPASLQSEEDIQ 369

  Fly   307 ----QPCCQA-------------------------------------------------LYDFEP 318
                ||...|                                                 .|.|||
pombe   370 LSFKQPELSASSAELDEKLKSQCNVSPSPSNISDAPPSKLNRSYSSPLASISSRKVVRMKYSFEP 434

  Fly   319 ENPGELAFKENDIITLLNRVDDNWF-------EGAVNGRTGYFPQSY 358
            |...||..|:.|::.:|..:|:.|:       :|...|.||.||.:|
pombe   435 ETENELKLKKGDLLLVLKEIDEGWWVGEKLGEDGVFTGNTGMFPSNY 481

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
EndoA	NP_620122.2	BAR_Endophilin_A	25..246	CDD:153276	52/278 (19%)
		SH3_Endophilin_A	312..361	CDD:212737	20/103 (19%)
SPOM_SPBC19C2.10	NP_595695.1	BAR_MUG137_fungi	21..235	CDD:153277	49/234 (21%)
		SP1-4_N	<236..>375	CDD:425404	19/138 (14%)
		SH3	430..482	CDD:473055	19/52 (37%)