Protein Alignment EndoA and mug137

DIOPT Version :10

• Sequence 1: NP_620122.2
• Gene: EndoA / 42265
• FlyBaseID: FBgn0038659
• Length: 369
• Species: Drosophila melanogaster
• Sequence 2: NP_588493.1
• Gene: mug137 / 2539113
• PomBaseID: SPCC1919.11
• Length: 420
• Species: Schizosaccharomyces pombe
• Alignment Length: 373
• Identity: 84/373 - (22%)
• Similarity: 155/373 - (41%)
• Gaps: 59/373 - (15%)

  Fly    10 INKANQYMTEKMGGAEGTKLDMDFMEMERKTDVTVELVEELQLKTKEFLQPNPTARAKMAAVKGI 74
            :::...:..||..|.:...|...|:|:|::..:..|.:.:|...|..::.            ..:
pombe     2 VSRFFSWTNEKPLGDQRAHLPDSFLELEQEIAIREEGLSKLFQATTIWID------------SIL 54

  Fly    75 SKLSGQAKSNTYPQPEGLLAECMLTYGKKLGEDNSVFAQALVEFGEALKQMADVKYSLDDNIKQN 139
            .|:.|:.|........  |.:.|:.:.|:|.:|:| :...|.:.|:|..::.:.:.||....:..
pombe    55 KKVDGEDKEKCLACEN--LGKVMINHSKELPQDSS-YGITLSQLGKANLKIGEHQTSLAYKARVC 116

  Fly   140 FLEPL--HHMQTKDLKEVMHHRKKLQGRRLDFDC---KRRRQAKDD-----EIRGAEDKFGESLQ 194
            :|:.|  :.:|.||....   ||||:.||..::.   |..::.|:|     :||.|..||.||.:
pombe   117 YLDFLKRYLVQAKDFHSA---RKKLESRRQAYESLLQKSFKEKKEDSRLEEDIRLALYKFEESTE 178

  Fly   195 LAQVGMFNLLENDTEHVSQLVTFAEALYDFHSQCADVLRGL---QETL--QEKRSEAESRPRNEF 254
            ..:..|..|.:.:.:...||........:|..:...:|..:   |.:|  |:|...:|....|||
pombe   179 QVKNRMIALKDVEADQYQQLTELIVYELNFFKESTGILNTIFNSQNSLTPQKKIQSSERSVENEF 243

  Fly   255 VPKTLLDLNLDGGGGGLNEDGTPSHISSSASPLP--SPMRSPAKSMAVTPQRQQQPCCQALYDFE 317
            :...:        ...|::..|.:..:...||.|  :|.|...|.....         :|:|.|.
pombe   244 LASPM--------DPSLSKLFTKTTNTEKISPTPFSTPKRKSKKETVFV---------KAIYSFT 291

  Fly   318 PENPGELAFKENDIITLLNRVDDNWFEG-AVN------GRTGYFPQSY 358
            ..|..||.....|:|.:..::..:|:.| .||      |.:|.||.:|
pombe   292 GRNEKELDLHTGDVIQVSEQLGPDWYMGEKVNSKAEKLGNSGMFPVNY 339

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
EndoA	NP_620122.2	BAR_Endophilin_A	25..246	CDD:153276	52/235 (22%)
		SH3_Endophilin_A	312..361	CDD:212737	17/54 (31%)
mug137	NP_588493.1	BAR_MUG137_fungi	17..230	CDD:153277	50/230 (22%)
		SH3	280..341	CDD:214620	17/69 (25%)