Protein Alignment EndoA and Sh3gl3

DIOPT Version :10

• Sequence 1: NP_620122.2
• Gene: EndoA / 42265
• FlyBaseID: FBgn0038659
• Length: 369
• Species: Drosophila melanogaster
• Sequence 2: XP_030098123.1
• Gene: Sh3gl3 / 20408
• MGIID: 700011
• Length: 361
• Species: Mus musculus
• Alignment Length: 351
• Identity: 182/351 - (51%)
• Similarity: 235/351 - (66%)
• Gaps: 24/351 - (6%)

  Fly    18 TEKMGGAEGTKLDMDFMEMERKTDVTVELVEELQLKTKEFLQPNPTARAKMAAVKGISKLSGQAK 82
            :||:.||||||||.:|:.||:|.|:|.:.|.|:..|..|:|||||..|||:..:..:|||.||.|
Mouse    32 SEKISGAEGTKLDEEFLNMEKKIDITSKAVAEILSKATEYLQPNPAYRAKLGMLNTVSKLRGQVK 96

  Fly    83 SNTYPQPEGLLAECMLTYGKKLGEDNSVFAQALVEFGEALKQMADVKYSLDDNIKQNFLEPLHHM 147
            :..|||.||||.:|||.|||:|||| |.|..:||:.|||||.||:||.|||.|:||.|::||..:
Mouse    97 ATGYPQTEGLLGDCMLKYGKELGED-SAFGNSLVDVGEALKLMAEVKDSLDINVKQTFIDPLQLL 160

  Fly   148 QTKDLKEVMHHRKKLQGRRLDFDCKRRRQAK--DDEIRGAEDKFGESLQLAQVGMFNLLENDTEH 210
            |.|||||:.||.:||:|||||:|.|:||..|  ::|||.|.:||.||.:||:..|||.||||.|.
Mouse   161 QDKDLKEIGHHLRKLEGRRLDYDYKKRRVGKIPEEEIRQAVEKFEESKELAERSMFNFLENDVEQ 225

  Fly   211 VSQLVTFAEALYDFHSQCADVLRGLQETLQEKRSEAESRPRNEFVPKTLLDLNLDGGGGGLNEDG 275
            ||||..|.||..|:|.|..::|:.||..|:.:.|.|...|:.||:||.:...:.|..|.|
Mouse   226 VSQLAVFVEAALDYHRQSTEILQELQSKLELRISLASKVPKREFMPKPVNMSSTDANGVG----- 285

  Fly   276 TPSHISSSASPLPSPMRSPAKSMAVTPQRQQQPCCQALYDFEPENPGELAFKENDIITLLNRVDD 340
             ||  |||.:|             .|.....||||:.||||||||.|||.|||.|||||.|::|:
Mouse   286 -PS--SSSKTP-------------GTDTPSDQPCCRGLYDFEPENEGELGFKEGDIITLTNQIDE 334

  Fly   341 NWFEGAVNGRTGYFPQSYVQVQVPLP 366
            ||:||.:.|.:|:||.:||:|.||||
Mouse   335 NWYEGMLRGESGFFPINYVEVIVPLP 360

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
EndoA	NP_620122.2	BAR_Endophilin_A	25..246	CDD:153276	122/222 (55%)
		SH3_Endophilin_A	312..361	CDD:212737	31/48 (65%)
Sh3gl3	XP_030098123.1	BAR_Endophilin_A3	39..261	CDD:153299	122/222 (55%)
		SH3_Endophilin_A	302..356	CDD:212737	34/53 (64%)