DRSC/TRiP Functional Genomics Resources

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Protein Alignment EndoA and unc-57

DIOPT Version :10

Sequence 1:NP_620122.2 Gene:EndoA / 42265 FlyBaseID:FBgn0038659 Length:369 Species:Drosophila melanogaster
Sequence 2:NP_001122513.1 Gene:unc-57 / 172078 WormBaseID:WBGene00006791 Length:381 Species:Caenorhabditis elegans


Alignment Length:393 Identity:184/393 - (46%)
Similarity:250/393 - (63%) Gaps:41/393 - (10%)


- Green bases have known domain annotations that are detailed below.


  Fly     1 MAFAGLKKQINKANQYMTEKMGGAEGTKLDMDFMEMERKTDVTVELVEELQLKTKEFLQPNPTAR 65
            |:.:||:||.||||||::|.||.||.||||..|.|||:..|.|..|:.:|...|.|:|||||..|
 Worm     1 MSLSGLRKQFNKANQYLSETMGAAEPTKLDDVFNEMEKNVDTTYNLITDLVAGTNEYLQPNPATR 65

  Fly    66 AKMAAVKGISKLSGQAKSNTYPQPEGLLAECMLTYGKKLGEDNSVFAQALVEFGEALKQMADVKY 130
            ||||....:||:.|..|::.|||.||:||:.|..||::|| |||...::|.:..|..:||||:||
 Worm    66 AKMATQVALSKVRGTTKTSPYPQTEGMLADVMQKYGQQLG-DNSDLGKSLNDAAETYRQMADIKY 129

  Fly   131 SLDDNIKQNFLEPLHHMQTKDLKEVMHHRKKLQGRRLDFDCKRRRQAKDDEIRGAEDKFGESLQL 195
            .::||:|||||:||.|:|..:||:|.|||.||:|||||:|||:|:|.:|||:..||:|..||.:|
 Worm   130 QMEDNVKQNFLDPLTHLQNNELKDVNHHRTKLKGRRLDYDCKKRQQRRDDEMIQAEEKLEESKRL 194

  Fly   196 AQVGMFNLLENDTEHVSQLVTFAEALYDFHSQCADVLRGLQETLQEKRSEAESRPRNEFVPKTLL 260
            |::.|||:|.||.|.:|||....||..|||.|.|..|..||:.|..:..:|.:|||.|.||.::|
 Worm   195 AEMSMFNVLSNDVEQISQLRALIEAQLDFHRQTAQCLENLQQQLGHRIKDAAARPREEHVPLSVL 259

  Fly   261 DLNLDGGGGGLNEDGTPSHISSSASPLPSPM---RSPAKSMAVTPQ------------------- 303
                      .||..||.  ||..||.||.|   .:.|.:..:.||                   
 Worm   260 ----------ANESRTPR--SSFRSPAPSDMSHNSTAAAAFKMPPQNGGGITQAPPSYQGPPPGG 312

  Fly   304 ------RQQQPCCQALYDFEPENPGELAFKENDIITLLNRVDDNWFEGAVNGRTGYFPQSYVQVQ 362
                  :||:|.|:||:||:.::.|||.|||..:|.|::::|:||:||.|||:||.||.:||||.
 Worm   313 LPPPLSQQQKPQCRALFDFDAQSEGELDFKEGTLIELVSQIDENWYEGRVNGKTGLFPVTYVQVL 377

  Fly   363 VPL 365
            |||
 Worm   378 VPL 380

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
EndoANP_620122.2 BAR_Endophilin_A 25..246 CDD:153276 112/220 (51%)
SH3_Endophilin_A 312..361 CDD:212737 26/48 (54%)
unc-57NP_001122513.1 BAR_Endophilin_A 25..245 CDD:153276 112/220 (51%)
SH3_Endophilin_A 323..377 CDD:212737 29/53 (55%)

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